Mechanism of DNA unwinding by MCM8-9 in complex with HROB

In a new study published in “Nature Communications” the Cejka laboratory and collaborators identified the molecular mechanisms by which the HROB protein enhances the DNA unwinding function of the MCM8-9 helicase, crucial for DNA repair and replication processes. Bellinzona, May 2, 2024 – The MCM8-9 helicase and the HROB proteins function together in DNA repair. […]
Bios+ Open Day

The Institute for Research in Biomedicine (IRB), the Institute of Oncology Research (IOR) and the laboratories for translational research of the EOC invite you to the open day that will take place on Saturday May 25th from 9:00 a.m. to 1:00 p.m at Bios+ (Via Francesco Chiesa 5, 6500 Bellinzona). This is an opportunity to […]
Bios+ Open Day
The Institute for Research in Biomedicine (IRB), the Institute of Oncology Research (IOR) and the laboratories for translational research of the EOC invite you to the open day that will take place on Saturday May 25th from 9:00 a.m. to 1:00 p.m at Bios+ (Via Francesco Chiesa 5, 6500 Bellinzona). This is an opportunity to […]
The ocean microbiome as a genomic treasure trove
Prof. Shinichi Sunagawa Department of Biology, Institute of Microbiology, ETH Zurich Thursday, May 23, 2024 at 4:00 pm Bios+ Seminar Room Contact: Prof. Davide Robbiani This event is supported by the IRB-Rockefeller University partnership for infectious disease research.
Transformer-based spatial-temporal detection of apoptotic cell death in live-cell imaging

Apoptotic cell death is a crucial mechanism that contributes to tissue homeostasis and prevents the onset of several diseases. However, this phenomenon is challenging to identify within microscopy movies that can encompass thousands of cells. Led by Santiago Gonzalez, the recent study carried at the IRB in Bellinzona introduces ADeS, an innovative approach based on […]
Bones & beyond: Uncovering the ossification and cytotoxic role of CD8 T cells in ankylosing spondylitis

A recent study, published in RMD Open, by Martini et al. has identified, in patients with ankylosing spondylitis (AS), high cytotoxic CD8 T cells upregulating chemokine receptors along with genes promoting the ossification process, paving the way to new therapeutic targets for the treatment of AS. Bellinzona, April 15, 2024 – Ankylosing spondylitis (AS) is […]
Reprogramming of host energy metabolism and pro-inflammatory response in malaria
International PhD Program in Immunology, Cell Biology and Biochemistry 2023/2024 Prof. Ricardo Gazzinelli Oswaldo Cruz Foundation – Minas (BR) Tuesday, May 14, 2024 at 12 pm Bios+ Seminar Room Contact: Dr. Caroline Junqueira
Bridging the Gap between Science and Technology for Chemical Analysis Methods
IRB Special Seminar Prof. Davide Bleiner President DAS (Division Analytical Science), Swiss Chemical Society Thursday, May 3, 2024 at 11:00 am Bios+ Seminar Room
T cell subsets regulating the germinal center reaction
IRB Special Seminar Prof. Johanne T. Jacobsen Department of Clinical Medicine, Oslo University Hospital (NO) Thursday, May 2, 2024 at 12:00 pm Bios+ Seminar Room Contact: Dr. Silvia Monticelli
Breast tumor heterogeneity and metastasis: Act locally, think globally
IRB/IOR Special Seminar Prof. Mohamed Bentires-Alj Professor of Experimental Surgical Oncology Faculty of Medicine, Department of Biomedicine | University of Basel | University Hospital Basel (CH) Thursday, April 25, 2024 at 12:00 pm Bios+ Seminar Room Contacts: Prof. Greta Guarda, Dr. Arianna Calcinotto