Publications - IRB USI

Publications

Validation of a highly sensitive HaloTag-based assay to evaluate the potency of a novel class of allosteric beta-Galactosidase correctors
Rudinskiy, M. Pons-Vizcarra, M. Solda, T. Fregno, I. Bergmann, T. J. Ruano, A. Delgado, A. Morales, S. Barril, X. Bellotto, M. Cubero, E. Garcia-Collazo, A. M. Perez-Carmona, N. Molinari, M.
in PLoS One (2023) Vol.18 ppe0294437
PI3Kdelta activation, IL6 over-expression, and CD37 loss cause resistance to the targeting of CD37-positive lymphomas with the antibody-drug conjugate naratuximab emtansine
Arribas, A. J. Gaudio, E. Napoli, S. Yvon Herbaux, C. J. Tarantelli, C. Bordone, R. P. Cascione, L. Munz, N. Aresu, L. Sgrignani, J. Rinaldi, A. Kwee, I. Rossi, D. Cavalli, A. Zucca, E. Stussi, G. Stathis, A. Sloss, C. Davids, M. S. Bertoni, F.
in bioRxiv (2023) Vol. pp
CD304+ adipose tissue-derived mesenchymal stem cell abundance in autologous fat grafts highly correlates with improvement of localized pain syndromes
Rezzonico Jost, T. Lozito, A. Mangani, D. Raimondi, A. Klinger, F. Morone, D. Klinger, M. Grassi, F. Vinci, V.
in Pain (2023) Vol. pp
Tau accumulation in degradative organelles is associated to lysosomal stress
Piovesana, E. Magrin, C. Ciccaldo, M. Sola, M. Bellotto, M. Molinari, M. Papin, S. Paganetti, P.
in Sci Rep (2023) Vol.13 pp18024
Human MCTS1-dependent translation of JAK2 is essential for IFN-gamma immunity to mycobacteria
Bohlen, J. Zhou, Q. Philippot, Q. Ogishi, M. Rinchai, D. Nieminen, T. Seyedpour, S. Parvaneh, N. Rezaei, N. Yazdanpanah, N. Momenilandi, M. Conil, C. Neehus, A. L. Schmidt, C. Arango-Franco, C. A. Voyer, T. L. Khan, T. Yang, R. Puchan, J. Erazo, L. Roiuk, M. Vatovec, T. Janda, Z. Bagaric, I. Materna, M. Gervais, A. Li, H. Rosain, J. Peel, J. N. Seeleuthner, Y. Han, J. E. L'Honneur, A. S. Moncada-Velez, M. Martin-Fernandez, M. Horesh, M. E. Kochetkov, T. Schmidt, M. AlShehri, M. A. Salo, E. Saxen, H. ElGhazali, G. Yatim, A. Soudee, C. Sallusto, F. Ensser, A. Marr, N. Zhang, P. Bogunovic, D. Cobat, A. Shahrooei, M. Beziat, V. Abel, L. Wang, X. Boisson-Dupuis, S. Teleman, A. A. Bustamante, J. Zhang, Q. Casanova, J. L.
in Cell (2023) Vol. pp
The Shigella flexneri virulence factor apyrase is released inside eukaryotic cells to hijack host cell fate
Perruzza, L. Zagaglia, C. Vitiello, L. Sarshar, M. Strati, F. Pasqua, M. Grassi, F. Nicoletti, M. Palamara, A. T. Ambrosi, C. Scribano, D.
in Microbiol Spectr (2023) Vol. ppe0077523
Analytical Ultracentrifugation Detects Quaternary Rearrangements and Antibody-Induced Conformational Selection of the SARS-CoV-2 Spike Trimer
Guerrini, G. Mehn, D. Fumagalli, F. Gioria, S. Pedotti, M. Simonelli, L. Bianchini, F. Robbiani, D. F. Varani, L. Calzolai, L.
in Int J Mol Sci (2023) Vol.24 pp
Regulatory circuits of mitophagy restrict distinct modes of cell death during memory CD8(+) T cell formation
Franco, F. Bevilacqua, A. Wu, R. M. Kao, K. C. Lin, C. P. Rousseau, L. Peng, F. T. Chuang, Y. M. Peng, J. J. Park, J. Xu, Y. Cassotta, A. Yu, Y. R. Speiser, D. E. Sallusto, F. Ho, P. C.
in Sci Immunol (2023) Vol.8 ppeadf7579
A combination of two resistance mechanisms is critical for tick-borne encephalitis virus escape from a broadly neutralizing human antibody
Svoboda, P. Haviernik, J. Bednar, P. Matkovic, M. Cervantes Rincon, T. Keeffe, J. Palus, M. Salat, J. Agudelo, M. Nussenzweig, M. C. Cavalli, A. Robbiani, D. F. Ruzek, D.
in Cell Rep (2023) Vol.42 pp113149
The P2X7 Receptor in Autoimmunity
Grassi, F. Salina, G.
in Int J Mol Sci (2023) Vol.24 pp
The interplay between previous infection and mental health condition on antibody response to COVID-19 mRNA vaccination
Grignoli, N. Petrocchi, S. Polito, A. Gagliano, V. Sallusto, F. Uguccioni, M. Gabutti, L.
in Brain Behav Immun Health (2023) Vol.33 pp100677
Adapting Neutralizing Antibodies to Viral Variants by Structure-Guided Affinity Maturation Using Phage Display Technology
Peissert, F. Pedotti, M. Corbellari, R. Simonelli, L. De Gasparo, R. Tamagnini, E. Plüss, L. Elsayed, A. Matasci, M. De Luca, R. Cassaniti, I. Sammartino, J. C. Piralla, A. Baldanti, F. Neri, D. Varani, L.
in Global Challenges (2023) Vol. pp
ETS1 phosphorylation at threonine 38 is associated with the cell of origin of diffuse large B cell lymphoma and sustains the growth of tumour cells
Chung, E. Y. L. Sartori, G. Ponzoni, M. Cascione, L. Priebe, V. Xu-Monette, Z. Y. Fang, X. Zhang, M. Visco, C. Tzankov, A. Rinaldi, A. Sgrignani, J. Zucca, E. Rossi, D. Cavalli, A. Inghirami, G. Scott, D. W. Young, K. H. Bertoni, F.
in Br J Haematol (2023) Vol. pp
GPR182 is a broadly scavenging atypical chemokine receptor influencing Tindependent immunity
Melgrati, S. Gerken, O. J. Artinger, M. Radice, E. Szpakowska, M. Chevigné, A., D’Uonnolo, G. Antonello, P. Thelen, S. Pelczar, P. Legler, D. Thelen, M.
in Front. Immunol. (2023) Vol.14 pp1242531.
The mRNA methyltransferase Mettl3 modulates cytokine mRNA stability and limits functional responses in mast cells
Leoni, C. Bataclan, M. Ito-Kureha, T. Heissmeyer, V. Monticelli, S.
in Nat Commun (2023) Vol.14 pp3862
Tau protein binds to the P53 E3 ubiquitin ligase MDM2
Sola, M. Rendon-Angel, A. Rojo Martinez, V. Sgrignani, J. Magrin, C. Piovesana, E. Cavalli, A. Paganetti, P. Papin, S.
in Sci Rep (2023) Vol.13 pp10208
Mechanistic Insights into the Antibiofilm Mode of Action of Ellagic Acid
Ratti, A. Fassi, E. M. A. Forlani, F. Mori, M. Villa, F. Cappitelli, F. Sgrignani, J. Roda, G. Cavalli, A. Villa, S. Grazioso, G.
in Pharmaceutics (2023) Vol.15 pp
TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ER stress
Kucinska, M. K. Fedry, J. Galli, C. Morone, D. Raimondi, A. Solda, T. Forster, F. Molinari, M.
in Nat Commun (2023) Vol.14 pp3497
Mechanism of DNA unwinding by hexameric MCM8-9 in complex with HROB
Acharya, A. Bret, H. Huang, J. W. Mutze, M. Gose, M. Kissling, V. Seidel, R. Ciccia, A. Guerois, R. Cejka, P.
in bioRxiv (2023) Vol. pp
ER-to-Lysosome Associated Degradation (ERLAD) in a Nutshell: mammalian, yeast and plant ER-phagy as induced by misfolded proteins
Rudinskiy, M. Molinari, M.
in FEBS Lett (2023) Vol. pp
Rescue of secretion of a rare-disease associated mis-folded mutant glycoprotein in UGGT1 knock-out mammalian cells
Tax, G. Guay, K. P. Solda, T. Hitchman, C. J. Hill, J. C. Vasiljevic, S. Lia, A. Modenutti, C. P. Straatman, K. R. Santino, A. Molinari, M. Zitzmann, N. Hebert, D. N. Roversi, P. Trerotola, M.
in bioRxiv (2023) Vol. pp
Proteomics of immune cells from liver tumors reveals immunotherapy targets
Canale, F. P. Neumann, J. von Renesse, J. Loggi, E. Pecoraro, M. Vogel, I. Zoppi, G. Antonini, G. Wolf, T. Jin, W. Zheng, X. La Barba, G. Birgin, E. Forkel, M. Nilsson, T. Marone, R. Mueller, H. Pelletier, N. Jeker, L. T. Civenni, G. Schlapbach, C. Catapano, C. V. Seifert, L. Seifert, A. M. Gillessen, S. De Dosso, S. Cristaudi, A. Rahbari, N. N. Ercolani, G. Geiger, R.
in Cell Genom (2023) Vol.3 pp100331
Reassessing the adrenomedullin scavenging function of ACKR3 in lymphatic endothelial cells
Sigmund, E. C. Bauer, A. Jakobs, B. D. Tatliadim, H. Tacconi, C. Thelen, M. Legler, D. F. Halin, C.
in PLoS One (2023) Vol.18 ppe0285597
Machine learning analysis of humoral and cellular responses to SARS-CoV-2 infection in young adults
Marcinkevics, R. Silva, P. N. Hankele, A. K. Dornte, C. Kadelka, S. Csik, K. Godbersen, S. Goga, A. Hasenohrl, L. Hirschi, P. Kabakci, H. LaPierre, M. P. Mayrhofer, J. Title, A. C. Shu, X. Baiioud, N. Bernal, S. Dassisti, L. Saenz-de-Juano, M. D. Schmidhauser, M. Silvestrelli, G. Ulbrich, S. Z. Ulbrich, T. J. Wyss, T. Stekhoven, D. J. Al-Quaddoomi, F. S. Yu, S. Binder, M. Schultheibeta, C. Zindel, C. Kolling, C. Goldhahn, J. Seighalani, B. K. Zjablovskaja, P. Hardung, F. Schuster, M. Richter, A. Huang, Y. J. Lauer, G. Baurmann, H. Low, J. S. Vaqueirinho, D. Jovic, S. Piccoli, L. Ciesek, S. Vogt, J. E. Sallusto, F. Stoffel, M. Ulbrich, S. E.
in Front Immunol (2023) Vol.14 pp1158905
The chemokine landscape: one system multiple shades
Cecchinato, V. Martini, V. Pirani, E. Ghovehoud, E. Uguccioni, M.
in Front Immunol (2023) Vol.14 pp1176619
Atlas of the anatomical localization of atypical chemokine receptors in healthy mice
Melgrati, S. Radice, E. Ameti, R. Hub, E. Thelen, S. Pelczar, P. Jarrossay, D. Rot, A. Thelen, M.
in PLoS Biol (2023) Vol.21 ppe3002111
Myc controls NK cell development, IL-15-driven expansion, and translational machinery
Khameneh, H. J. Fonta, N. Zenobi, A. Niogret, C. Ventura, P. Guerra, C. Kwee, I. Rinaldi, A. Pecoraro, M. Geiger, R. Cavalli, A. Bertoni, F. Vivier, E. Trumpp, A. Guarda, G.
in Life Sci Alliance (2023) Vol.6 ppe202302069.
New pairings and deorphanization among the atypical chemokine receptor family – physiological and clinical relevance
Szpakowska, M. D'Uonnolo, G. Luis, R. Alonso Bartolome, A. Thelen, M. Legler, D. F. Chevigne, A.
in Front Immunol (2023) Vol.14 pp1133394
The P2X7 receptor in mucosal adaptive immunity
Grassi, F. Marino, R.
in Purinergic Signal (2023) Vol. pp
Heterologous inactivated virus/mRNA vaccination response to BF.7, BQ.1.1, and XBB.1
Zuo, F. Sun, R. Abolhassani, H. Du, L. Wang, Y. Vlachiotis, S. Bertoglio, F. Schubert, M. Rezaei, N. Chavoshzadeh, Z. Guerra, C. Cavalli, A. Andrell, J. Kumagai-Braesch, M. Xue, Y. Cao, Y. Hust, M. Robbiani, D. F. Xie, X. S. Hammarstrom, L. Marcotte, H. Pan-Hammarstrom, Q.
in Lancet Reg Health West Pac (2023) Vol.33 pp100762
SHP-1 localization to the activating immune synapse promotes NK cell tolerance in MHC class I deficiency
Schmied, L. Luu, T. T. Sondergaard, J. N. Hald, S. H. Meinke, S. Mohammad, D. K. Singh, S. B. Mayer, C. Perinetti Casoni, G. Chrobok, M. Schlums, H. Rota, G. Truong, H. M. Westerberg, L. S. Guarda, G. Alici, E. Wagner, A. K. Kadri, N. Bryceson, Y. T. Saeed, M. B. Hoglund, P.
in Sci Signal (2023) Vol.16 ppeabq0752
Editorial: Insights in cytokines and soluble mediators in immunity: 2022
Melgrati, S. Sozzani, S. Thelen, M.
in Front Immunol (2023) Vol.14 pp1194553
Phase separation properties of RPA combine high-affinity ssDNA binding with dynamic condensate functions at telomeres
Spegg, V. Panagopoulos, A. Stout, M. Krishnan, A. Reginato, G. Imhof, R. Roschitzki, B. Cejka, P. Altmeyer, M.
in Nat Struct Mol Biol (2023) Vol.30 pp451-462.
Esmethadone-HCl (REL-1017): a promising rapid antidepressant
Fava, M. Stahl, S. M. De Martin, S. Mattarei, A. Bettini, E. Comai, S. Alimonti, A. Bifari, F. Pani, L. Folli, F. Guidetti, C. Furlan, A. Sgrignani, J. Locatelli, P. Cavalli, A. O'Gorman, C. Traversa, S. Inturrisi, C. E. Pappagallo, M. Manfredi, P. L.
in Eur Arch Psychiatry Clin Neurosci (2023) Vol. pp
Sequence and chromatin features guide DNA double-strand break resection initiation
Gnugge, R. Reginato, G. Cejka, P. Symington, L. S.
in Mol Cell (2023) Vol.83 pp1237-1250.

Istituto di Ricerca in Biomedicina

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