Publications - IRB USI

Publications

Sae2 controls Mre11 endo- and exonuclease activities by different mechanisms
Tamai, T. Reginato, G. Ojiri, R. Morita, I. Avrutis, A. Cejka, P. Shinohara, M. Sugimoto, K.
in Nat Commun (2024) Vol.15 pp7221
Stealth mRNA nanovaccines to control lymph node trafficking
Garcia-Fernandez, C. Virgilio, T. Latino, I. Guerra-Rebollo, M. Gonzalez, S. F. Borros, S. Fornaguera, C.
in J Control Release (2024) Vol. pp
HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability
Bai, G. Endres, T. Kuhbacher, U. Mengoli, V. Greer, B. H. Peacock, E. M. Newton, M. D. Stanage, T. Dello Stritto, M. R. Lungu, R. Crossley, M. P. Sathirachinda, A. Cortez, D. Boulton, S. J. Cejka, P. Eichman, B. F. Cimprich, K. A.
in Mol Cell (2024) Vol.84 pp3044-3060.
Persistent longitudinal T cell responses after SARS-CoV-2 mRNA vaccines in MS patients on different disease modifying treatments
Disanto, G. Galante, A. Sacco, R. Mallucci, G. Mele, F. Sallusto, F. Zecca, C. Gobbi, C.
in Mult Scler Relat Disord (2024) Vol.90 pp105813
NLRC5: back to innate immunity
Guerra, J. Guarda, G.
in Trends Immunol (2024) Vol.45 pp571-573
Site-specific serology unveils cross-reactive monoclonal antibodies targeting influenza A hemagglutinin epitopes
Paparoditis, P. C. G. Fruehwirth, A. Bevc, K. Low, J. S. Jerak, J. Terzaghi, L. Foglierini, M. Fernandez, B. Jarrossay, D. Corti, D. Sallusto, F. Lanzavecchia, A. Cassotta, A.
in Eur J Immunol (2024) Vol. ppe2451045
BACH2 regulates diversification of regulatory and proinflammatory chromatin states in T(H)17 cells
Thakore, P. I. Schnell, A. Huang, L. Zhao, M. Hou, Y. Christian, E. Zaghouani, S. Wang, C. Singh, V. Singaraju, A. Krishnan, R. K. Kozoriz, D. Ma, S. Sankar, V. Notarbartolo, S. Buenrostro, J. D. Sallusto, F. Patsopoulos, N. A. Rozenblatt-Rosen, O. Kuchroo, V. K. Regev, A.
in Nat Immunol (2024) Vol.25 pp1395-1410
HLTF disrupts Cas9-DNA post-cleavage complexes to allow DNA break processing
Reginato, G. Dello Stritto, M. R. Wang, Y. Hao, J. Pavani, R. Schmitz, M. Halder, S. Morin, V. Cannavo, E. Ceppi, I. Braunshier, S. Acharya, A. Ropars, V. Charbonnier, J. B. Jinek, M. Nussenzweig, A. Ha, T. Cejka, P.
in Nat Commun (2024) Vol.15 pp5789
A Menage a trois: NLRC5, immunity, and metabolism
Brunschwiler, F. Nakka, S. Guerra, J. Guarda, G.
in Front Immunol (2024) Vol.15 pp1426620
Targeting senescence induced by age or chemotherapy with a polyphenol-rich natural extract improves longevity and healthspan in mice
Zumerle, S. Sarill, M. Saponaro, M. Colucci, M. Contu, L. Lazzarini, E. Sartori, R. Pezzini, C. Rinaldi, A. Scanu, A. Sgrignani, J. Locatelli, P. Sabbadin, M. Valdata, A. Brina, D. Giacomini, I. Rizzo, B. Pierantoni, A. Sharifi, S. Bressan, S. Altomare, C. Goshovska, Y. Giraudo, C. Luisetto, R. Iaccarino, L. Torcasio, C. Mosole, S. Pasquini, E. Pellegrini, L. Peron, G. Fassan, M. Masiero, S. Giori, A. M. Dall'Acqua, S. Auwerx, J. Cippa, P. Cavalli, A. Bolis, M. Sandri, M. Barile, L. Montopoli, M. Alimonti, A.
in Nat Aging (2024) Vol. pp
Protection from environmental enteric dysfunction and growth improvement in malnourished newborns by amplification of secretory IgA
Perruzza, L. Rezzonico Jost, T. Raneri, M. Gargari, G. Palatella, M. De Ponte Conti, B. Seehusen, F. Heckmann, J. Viemann, D. Guglielmetti, S. Grassi, F.
in Cell Rep Med (2024) Vol. pp101639
A first-in-class Wiskott-Aldrich syndrome protein activator with anti-tumor activity in hematologic cancers
Spriano, F. Sartori, G. Sgrignani, J. Barnabei, L. Arribas, A. J. Guala, M. Del Amor, A. M. C. Tomasso, M. R. Tarantelli, C. Cascione, L. Golino, G. Riveiro, M. E. Bortolozzi, R. Lupia, A. Paduano, F. Huguet, S. Rezai, K. Rinaldi, A. Margheriti, F. Ventura, P. Guarda, G. Costa, G. Rocca, R. Furlan, A. Verdonk, L. M. Innocenti, P. Martin, N. I. Viola, G. Driessen, C. Zucca, E. Stathis, A. Gahtory, D. Van den Nieuwboer, M. Bornhauser, B. Alcaro, S. Trapasso, F. Cristobal, S. Padrick, S. B. Pazzi, N. Cavalli, F. Cavalli, A. Gaudio, E. Bertoni, F.
in Haematologica (2024) Vol. pp
Structure and repair of replication-coupled DNA breaks
Pavani, R. Tripathi, V. Vrtis, K. B. Zong, D. Chari, R. Callen, E. Pankajam, A. V. Zhen, G. Matos-Rodrigues, G. Yang, J. Wu, S. Reginato, G. Wu, W. Cejka, P. Walter, J. C. Nussenzweig, A.
in Science (2024) Vol.385 ppeado3867
Rad51 determines pathway usage in post-replication repair
Meyer, D. Ceballos, S. J. Gore, S. Liu, J. Reginato, G. Cano-Linares, M. I. Maslowska, K. H. Villafanez, F. Ede, C. Pages, V. Prado, F. Cejka, P. Heyer, W. D.
in bioRxiv (2024) Vol. pp
Molecular insights into the activation of Mre11-Rad50 endonuclease activity by Sae2/CtIP
Nicolas, Y. Bret, H. Cannavo, E. Acharya, A. Cejka, P. Borde, V. Guerois, R.
in Mol Cell (2024) Vol.84 pp2223-2237 e4
Patient-derived organoid biobank identifies epigenetic dysregulation of intestinal epithelial MHC-I as a novel mechanism in severe Crohn’s Disease
Dennison, T. W. Edgar, R. D. Payne, F. Nayak, K. M. Ross, A. D. B. Cenier, A. Glemas, C. Giachero, F. Foster, A. R. Harris, R. Kraiczy, J. Salvestrini, C. Stavrou, G. Torrente, F. Brook, K. Trayers, C. Elmentaite, R. Youssef, G. Tel, B. Winton, D. J. Skoufou-Papoutsaki, N. Adler, S. Bufler, P. Azabdaftari, A. Jenke, A. G, N. Thomas, N. Miele, E. Al-Mohammad, A. Guarda, G. Kugathasan, S. Venkateswaran, S. Clatworthy, M. R. Castro-Dopico, T. Suchanek, O. Strisciuglio, C. Gasparetto, M. Lee, S. Xu, X. Bello, E. Han, N. Zerbino, D. R. Teichmann, S. A. Nys, J. Heuschkel, R. Perrone, F. Zilbauer, M.
in Gut (2024) Vol.73 pp1464-1477
Crosstalk between Regnase-1 and -3 shapes mast cell survival and cytokine expression
Bataclan, M. Leoni, C. Moro, S. G. Pecoraro, M. Wong, E. H. Heissmeyer, V. Monticelli, S.
in Life Sci Alliance (2024) Vol.7 pp
Human antibodies in Mexico and Brazil neutralizing tick-borne flaviviruses
Cervantes Rincon, T. Kapoor, T. Keeffe, J. R. Simonelli, L. Hoffmann, H. H. Agudelo, M. Jurado, A. Peace, A. Lee, Y. E. Gazumyan, A. Guidetti, F. Cantergiani, J. Cena, B. Bianchini, F. Tamagnini, E. Moro, S. G. Svoboda, P. Costa, F. Reis, M. G. Ko, A. I. Fallon, B. A. Avila-Rios, S. Reyes-Teran, G. Rice, C. M. Nussenzweig, M. C. Bjorkman, P. J. Ruzek, D. Varani, L. MacDonald, M. R. Robbiani, D. F.
in Cell Rep (2024) Vol.43 pp114298
ER-to-lysosome-associated degradation acts as failsafe mechanism upon ERAD dysfunction
Fasana, E. Fregno, I. Galli, C. Solda, T. Molinari, M.
in EMBO Rep (2024) Vol.25 pp2773-2785.
Tumor cells express and maintain HMGB1 in the reduced isoform to enhance CXCR4-mediated migration
Pirani, E. Paparoditis, P. Pecoraro, M. Danelon, G. Thelen, M. Cecchinato, V. Uguccioni, M.
in Front Immunol (2024) Vol.15 pp1358800
Mechanism of DNA unwinding by MCM8-9 in complex with HROB
Acharya, A. Bret, H. Huang, J. W. Mutze, M. Gose, M. Kissling, V. M. Seidel, R. Ciccia, A. Guerois, R. Cejka, P.
in Nat Commun (2024) Vol.15 pp3584
Computational Design of Novel Cyclic Peptides Endowed with Autophagy-Inhibiting Activity on Cancer Cell Lines
Albani, M. Fassi, E. M. A. Moretti, R. M. Garofalo, M. Montagnani Marelli, M. Roda, G. Sgrignani, J. Cavalli, A. Grazioso, G.
in Int J Mol Sci (2024) Vol.25 pp
Dbf4-dependent kinase promotes cell cycle controlled resection of DNA double-strand breaks and repair by homologous recombination
Galanti, L. Peritore, M. Gnugge, R. Cannavo, E. Heipke, J. Palumbieri, M. D. Steigenberger, B. Symington, L. S. Cejka, P. Pfander, B.
in Nat Commun (2024) Vol.15 pp2890
A critical view on autoantibodies in lupus nephritis: Concrete knowledge based on evidence
Bruschi, M. Angeletti, A. Prunotto, M. Meroni, P. L. Ghiggeri, G. M. Zeus, consortium Moroni, G. Sinico, R. A. Franceschini, F. Fredi, M. Vaglio, A. Cavalli, A. Scapozza, L. Patel, J. J. Tan, J. C. Lo, K. C. Cavagna, L. Petretto, A. Pratesi, F. Migliorini, P. Locatelli, F. Pazzola, G. Pesce, G. Giannese, D. Manfredi, A. Ramirez, G. A. Esposito, P. Murdaca, G. Negrini, S. Bui, F. Trezzi, B. Emmi, G. Cavazzana, I. Binda, V. Fenaroli, P. Pisan, I. Montecucco, C. Santoro, D. Scolari, F. Mescia, F. Volpi, S. Mosca, M. Tincani, A. Ravelli, A. Murtas, C. Candiano, G. Caridi, G. La Porta, E. Verrina, E.
in Autoimmun Rev (2024) Vol.23 pp103535
Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer
Cortesi, A. Gandolfi, F. Arco, F. Di Chiaro, P. Valli, E. Polletti, S. Noberini, R. Gualdrini, F. Attanasio, S. Citron, F. Ho, I. L. Shah, R. Yen, E. Y. Spinella, M. C. Ronzoni, S. Rodighiero, S. Mitro, N. Bonaldi, T. Ghisletti, S. Monticelli, S. Viale, A. Diaferia, G. R. Natoli, G.
in Sci Adv (2024) Vol.10 ppeadk5386

Istituto di Ricerca in Biomedicina

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