Castelgrande Lecture 2025 press-release

The sixth edition of the Calstelgrande Lecture, a scientific outreach event that brings distinguished figures in the field closer to the general public, was a great success. This year’s theme was “How microbes can help tackle climate change”, Prof. Rino Rappuoli. Bellinzona, 30 September 2025. As is now tradition, the sixth edition of the Castelgrande […]
Come i microbi possono aiutare ad affrontare i cambiamenti climatici
Prof. Rino Rappuoli Biotecnopolo Foundation, Siena, IT Tuesday, 30 September 2025 at 5:00 pm Bios+ Seminar Room
Development, maintenance, and function of alveolar macrophages
Prof. Manfred Kopf ETH Zürich– CH Friday, 26 September 2025 at 4:00 pm Bios+ Seminar Room
Decoding flavivirus biology using human brain organoids
Prof. Marco Alves University of Bern – CH Thursday, 11 September 2025 at 4:00 pm Bios+ Seminar Room
Artificial Intelligence designs miniproteins to control brain inflammation

Researcher from the Computational Structural Biology group at the Institute for Research in Biomedicine (IRB, Università della Svizzera italiana), have shown that artificial intelligence (AI) can design a potent novel miniprotein for lipocalin-2 (LCN2), a protein linked to neuroinflammation. Their study, published in Frontiers in Immunology and titled “AI-assisted design of ligands for lipocalin-2” by […]
Tissue Macrophage Heterogeneity
Prof. Florent Ginhoux Gustave Roussy Foundation – France Thursday, 23 September 2025 at 2:30 pm Bios+ Seminar Room
The IRB celebrates its 25th anniversary

Today, September 6, 2025, the celebration of the 25th anniversary of the Institute for Research in Biomedicine (IRB) took place. Among the many attendees were federal and cantonal political authorities: the Deputy Director of the State Secretariat for Education, Research and Innovation and Head of the National Division for Research and Innovation Dr. Laetitia Philippe, […]
Greta Guarda nominated President of the Swiss Society for Allergology and Immunology

Professor Greta Guarda, Director of the Laboratory of Immune System Mechanisms at the Institute for Research in Biomedicine affiliated with USI, and Full Professor at the Faculty of Biomedical Sciences, has been elected President of the Swiss Society for Allergology and Immunology (SSAI) until 2027. The handover of the presidency took place in Lausanne on […]
The hidden signal that allows cells to remove damaged organelles

A new study by the Institute for Research in Biomedicine (IRB), affiliated with Università della Svizzera italiana (USI), reveals how our cells recognise and selectively dispose of their damaged organelles. Published in the prestigious journal Nature Cell Biology, the study titled “The intrinsically disordered regions of organellophagy receptors are interchangeable and control organelle fragmentation, ER-phagy and mitophagy […]
A new Research Group at the IRB led by Dr. Samuel Nobs

Samuel Philip Nobs, PhD, will join the Institute for Research in Biomedicine (IRB) as Group Leader in August 2025, to study the interplay between microbiome and lung immune system. His research program will further strengthen the biomedical cluster that is developing at the Bellinzona Institutes of Science (Bios+). Bellinzona, July 31, 2025 – The Foundation […]
