Publications Archive

Virus-Like Particles and Nanoparticles for Vaccine Development against HCMV
Perotti, M. Perez, L.
in Viruses (2020) Vol.12 pppii: E35
An MVA Vector Expressing HIV-1 Envelope under the Control of a Potent Vaccinia Virus Promoter as a Promising Strategy in HIV/AIDS Vaccine Design
Perez, P. Marin, M. Q. Lazaro-Frias, A. Di Pilato, M. Gomez, C. E. Esteban, M. Garcia-Arriaza, J.
in Vaccines (Basel) (2019) Vol.7 pppii: E208
Regulatory Factor X 7 and its Potential Link to Lymphoid Cancers
Fischer, B. A. Chelbi, S. T. Guarda, G.
in Trends in Cancer (2019) Vol.6 pp
Early production of IL-17A by gammadelta T cells in the trachea promotes viral clearance during influenza infection in mice
Palomino-Segura, M. Latino, I. Farsakoglu, Y. Gonzalez, S. F.
in Eur J Immunol (2019) Vol.50 pp97-109
CXCR3 Identifies Human Naive CD8(+) T Cells with Enhanced Effector Differentiation Potential
De Simone, G. Mazza, E. M. C. Cassotta, A. Kuka, M. Zanon, V. De Paoli, F. Scamardella, E. Metsger, M. Roberto, A. Pilipow, K. Colombo, F. S. Tenedini, E. Tagliafico, E. Gattinoni, L. Mavilio, D. Peano, C. Price, D. A. Singh, S. P. Farber, J. M. Serra, V. Cucca, F. Ferrari, F. Orru, V. Fiorillo, E. Iannacone, M. Chudakov, D. M. Sallusto, F. Lugli, E.
in J Immunol (2019) Vol.203 pp3179-3189
IL-10 producing regulatory and helper T-cells in systemic lupus erythematosus
Geginat, J. Vasco, M. Gerosa, M. Pagani, M. Grassi, F. Flavell, R. A. Meroni, P. Abrignani, S.
in Semin Immunol (2019) Vol.44 pp101330
Protoporphyrin IX tracer fluorescence modulation for improved brain tumor cell lines visualization
Piffaretti, D. Burgio, F. Thelen, M. Paganetti, P. Reinert, M. D'Angelo, M. L.
in J Photochem Photobiol B (2019) Vol.201 pp111640
SHP-2 in Lymphocytes’ Cytokine and Inhibitory Receptor Signaling
Niogret, C. Birchmeier, W. Guarda, G.
in Front Immunol (2019) Vol.10 pp2468
ESCRT-III-driven piecemeal micro-ER-phagy remodels the ER during recovery from ER stress
Loi, M. Raimondi, A. Morone, D. Molinari, M.
in Nat Commun (2019) Vol.10 pp5058
Design of polymeric nanocapsules to improve their lympho-targeting capacity
Crecente-Campo, J. Virgilio, T. Morone, D. Fernandez-Marino, I. Olivera, A. Varela-Calvino, R. Gonzalez, S. F. Alonso, M. J.
in Nanomedicine (Lond) (2019) Vol.14 pp3013-3033
Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles
Petrova, V. N. Sawatsky, B. Han, A. X. Walz, L. Parker, E. Pieper, K. Anderson, C. A. de Vries, R. D. Lanzavecchia, A. Kellam, P. von Messling, V. de Swart, R. L. Russell, C. A.
in Sci Immunol (2019) Vol.4 pppii: eaay6125
A trainable clustering algorithm based on shortest paths from density peaks
Pizzagalli, D. U. Gonzalez, S. F. Krause, R.
in Science Advances (2019) Vol.5 ppeaax3770
Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01
Pinto, D. Fenwick, C. Caillat, C. Guseva, S. Dehez, F. Chipot, C. Barbieri, S. Minola, A. Jarrossay, D. Tomaras, G. D. Shen, X. Riva, A. Tarkowski, M. Schwartz, O. Bruel, T. Dufloo, J. Seaman, M. S. Montefiori, D. C. Lanzavecchia, A. Corti, D. Pantaleo, G. Weissenhorn, W.
in Cell Host Microbe (2019) Vol.26 pp623-637
Editorial overview: Overview of the articles – special section on human immunology
Sallusto, F.
in Curr Opin Immunol (2019) Vol.59 ppvi
Arl13b Regulates Breast Cancer Cell Migration and Invasion by Controlling Integrin-Mediated Signaling
Casalou, C. Faustino, A. Silva, F. Vaqueirinho, D. Ferreira, A. Castanheira, P. Barona, T. Ramalho, J. S. Serpa, J. Felix, A. Barral, D. C.
in Cancers (Basel) (2019) Vol.11 pp
The challenges of primary biliary cholangitis: What is new and what needs to be done
Terziroli Beretta-Piccoli, B. Mieli-Vergani, G. Vergani, D. Adams, D. Alpini, G. Banales, J. M. Beuers, U. Bjornsson, E. Bowlus, C. Carbone, M. Chazouilleres, O. Dalekos, G. De Gottardi, A. Harada, K. Hirschfield, G. Invernizzi, P. Jones, D. Krawitt, E. Lanzavecchia, A. Lian, Z. X. Ma, X. Manns, M. Mavilio, D. Quigley, E. M. Sallusto, F. Shimoda, S. Strazzabosco, M. Swain, M. Tanaka, A.
in J Autoimmun (2019) Vol.105 pp102328
A single T cell epitope drives the neutralizing anti-drug antibody response to natalizumab in multiple sclerosis patients
Cassotta, A. Mikol, V. Bertrand, T. Le Parc, J. Ferrari, P. Dumas, J. Auer, M. Deisenhammer, F. Gastaldi, M. Franciotta, D. Silacci-Fregni, C. Fernandez Rodriguez, B. Giacchetto-Sasselli, I. Foglierini, M. Jarrossay, D. Geiger, R. Sallusto, F. Lanzavecchia, A. Piccoli, L.
in Nat Med (2019) Vol.25 pp1402-1407
Frequency determination of breast tumor-reactive CD4 and CD8 T cells in humans: unveiling the antitumor immune response
Pinho, M. P. Patente, T. A. Flatow, E. A. Barbuto, J. A. M.
in Oncoimmunology (2019) Vol.8 pp1607674
Protection against influenza infection requires early recognition by inflammatory dendritic cells through C-type lectin receptor SIGN-R1
Palomino-Segura, M. Perez, L. Farsakoglu, Y. Latino, I. D'Antuono, R. Chatziandreou, N. Pizzagalli, D. U. Wang, G. Garcia-Sastre, A. Sallusto, F. Carroll, M. C. Neyrolles, O. Gonzalez, S. F.
in Nat Microbiol (2019) Vol.4 pp1930-1940
The Tim-3-Galectin-9 Pathway and Its Regulatory Mechanisms in Human Breast Cancer
Yasinska, I. M. Sakhnevych, S. S. Pavlova, L. Teuscher Abeleira, A. M. Benlaouer, O. Goncalves Silva, I. Mosimann, M. Varani, L. Bardelli, M. Hussain, R. Siligardi, G. Cholewa, D. Berger, S. M. Gibbs, B. F. Ushkaryov, Y. A. Fasler-Kan, E. Klenova, E. Sumbayev, V. V.
in Front Immunol (2019) Vol.10 pp1594
Oxidation State Dependent Conformational Changes of HMGB1 Regulate the Formation of the CXCL12/HMGB1 Heterocomplex
V. Fassi, E. M. A. Sgrignani, J. D'Agostino, V. Cecchinato, G. Garofalo, M. Grazioso, G. Uguccioni, M. Cavalli, A.
in Comput Struct Biotechnol J (2019) Vol.17 pp886-894
Narcolepsy – clinical spectrum, aetiopathophysiology, diagnosis and treatment
Bassetti, C. L. A. Adamantidis, A. Burdakov, D. Gay, S. Kallweit, U. Khatami, R. Koning, F. Kornum, B. R. Lammers, G. J. Liblau, R. S. Luppi, P. H. Mayer, G. Pollmacher, T. Sakurai, T. Sallusto, F. Scammell, T. E. Tafti, M. Dauvilliers, Y.
in Nat Rev Neurol (2019) Vol.15 pp519-539
Identification of a Novel Non-desmoglein Autoantigen in Pemphigus Vulgaris
Di Lullo, G. Calabresi, V. Mariotti, F. Lanzavecchia, A. Di Zenzo, G.
in Front Immunol (2019) Vol.10 pp1391
Enrichment of intestinal Lactobacillus by enhanced secretory IgA coating alters glucose homeostasis in P2rx7(-/-) mice
Perruzza, L. Strati, F. Gargari, G. Fosso, B. Pesole, G. Guglielmetti, S. Grassi, F.
in Sci Rep (2019) Vol.9 pp9315
The ETS Inhibitors YK-4-279 and TK-216 Are Novel Antilymphoma Agents
Spriano, F. Chung, E. Y. L. Gaudio, E. Tarantelli, C. Cascione, L. Napoli, S. Jessen, K. Carrassa, L. Priebe, V. Sartori, G. Graham, G. Selvanathan, S. P. Cavalli, A. Rinaldi, A. Kwee, I. Testoni, M. Genini, D. Ye, B. H. Zucca, E. Stathis, A. Lannutti, B. Toretsky, J. A. Bertoni, F.
in Clin Cancer Res (2019) Vol.25 pp5167-5176
The first‐in‐class ETS inhibitor TK‐216 interferes with ETS transcription factors and synergize with lenalidomide in lymphoma
Spriano, F. Chung,E. Napoli, S. Gaudio, E. Cascione, L. Cavalli, A. Rinaldi, A. Kwee, I. Ye, H. Rossi, D. Zucca, E. Stathis, A. Jessen, K. Lannutti, B. Toretsky, J. Bertoni, F.
in Hematological Oncology (2019) Vol.37 pp322
Competing interaction partners modulate the activity of Sgs1 helicase during DNA end resection
Kasaciunaite, K. Fettes, F. Levikova, M. Anand, R. Cejka, P. Seidel, R.
in EMBO J (2019) Vol.38 ppe101516
HCMV Envelope Glycoprotein Diversity Demystified
Foglierini, M. Marcandalli, J. Perez, L.
in Front Microbiol (2019) Vol.10 pp1005
Sumoylation regulates the stability and nuclease activity of Saccharomyces cerevisiae Dna2
Ranjha, L. Levikova, M. Altmannova, V. Cejka, P.
in Commun Biol (2019) Vol.2 pp174
Proteasomal and lysosomal clearance of faulty secretory proteins: ER-associated degradation (ERAD) and ER-to-lysosome-associated degradation (ERLAD) pathways
Fregno, I. Molinari, M.
in Crit Rev Biochem Mol Biol (2019) Vol.54 pp153-163
Proteolytic shedding of PrP can bemanipulatedin a substrate-specific manner bycertain PrP-binding ligands
Linsenmeier, L. Mohammadi, B. Shafiq, M. Frontzek, K. Puig, B. Li, C. Schweizer, M. Massignan, T. Biasini, E. Klein, A. Gilch, S. Varani, L. Schatzl, H. Aguzzi, A. Altmeppen, H. C. Glatzela, M.
in Prion (2019) Vol.13 pp108 -108
PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation
Wimmer, I. Tietz, S. Nishihara, H. Sallusto, F. Gosselet, F. Lyck, R. Muller, W. A. Lassmann, H. Engelhardt, B.
in Front Immunol (2019) Vol.10 pp711
Schwann cells ER-associated degradation contributes to myelin maintenance in adult nerves and limits demyelination in CMT1B mice
Volpi, V. G. Ferri, C. Fregno, I. Bianchi, F. Scapin, C. Pettinato, E. Solda, T. Feltri, M. L. Molinari, M. Wrabetz, L. D'Antonio, M.
in PLoS Genet (2019) Vol.15 ppe1008069
DDR1 role in fibrosis and its pharmacological targeting
Moll, S. Desmouliere, A. Moeller, M. J. Badi, L. Arcadu, F. Richter, H. Satz, A. Uhles, S. Cavalli, A. Drawnel, F. Scapozza, L. Prunotto, M.
in Biochim Biophys Acta Mol Cell Res (2019) Vol.1866 pp118474
Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells
Niogret, C. Miah, S. M. S. Rota, G. Wang, H. Held, W. Birchmeier, W. Sexl, V. Yang, W. Vivier, E. Ho, P. C. Brossay, L. Guarda, G.
in Nat Commun (2019) Vol.10 pp1444
The Skin Commensal Yeast Malassezia Triggers a Type 17 Response that Coordinates Anti-fungal Immunity and Exacerbates Skin Inflammation
Sparber, F. De Gregorio, C. Steckholzer, S. Dolowschiak, T. Ruchti, F. Kirchner, F. R. Mertens, S. Prinz, I. Joller, N. Buch, T. Glatz, M. Sallusto, F. LeibundGut-Landmann, S.
in Cell Host Microbe (2019) Vol.25 pp389-403 e6
free pdf: https://www.sciencedirect.com/science/article/pii/S1931312819300629?dgcid=coauthor
Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus
Marcandalli, J. Fiala, B. Ols, S. de van der Schueren, W. Snijder, J. Hodge, E. Benhaim, M. Ravichandran, R. Carter, L. Sheffler, W. Brunner, L. Lawrenz, M. Dubois, P. Lanzavecchia, A. Sallusto, F. Lee, K. K. Veesler, D. Correnti, C. E. Stewart, L. J. Baker, D. Lore, K. Perez, L. King, N. P.
in Cell (2019) Vol.176 pp1420-1431 e17
* J. Marcandalli and B. Fiala contributed equally to this work. L. Perez and N. P. King contributed equally to this work and are co-corresponding authors.
Seeing is believing: DNA zipping promotes DNA repair
Cejka, P.
in J Biol Chem (2019) Vol.294 pp3321-3322
Stepwise 5′ DNA end-specific resection of DNA breaks by the Mre11-Rad50-Xrs2 and Sae2 nuclease ensemble
Cannavo, E. Reginato, G. Cejka, P.
in Proc Natl Acad Sci U S A (2019) Vol.116 pp5505-5513
Influenza Vaccination Induces NK-Cell-Mediated Type-II IFN Response that Regulates Humoral Immunity in an IL-6-Dependent Manner
Farsakoglu, Y. Palomino-Segura, M. Latino, I. Chatziandreou, N. Pizzagalli, D. U. Rinaldi, A. Bolis, M. Sallusto, F. Stein, J. V. Gonzalez, S. F.
in Cell Rep (2019) Vol.26 pp2307-2315
DNA (Hydroxy)Methylation in T Helper Lymphocytes
Monticelli, S.
in Trends Biochem Sci (2019) Vol.44 pp589-598
Persistent Antibody Clonotypes Dominate the Serum Response to Influenza over Multiple Years and Repeated Vaccinations
Lee, J. Paparoditis, P. Horton, A. P. McDaniel, J. R. Jung, J. Boutz, D. R. Hussein, D. A. Tanno, Y. Pappas, L. Ippolito, G. C. Corti, D. Lanzavecchia, A. Georgiou, G.
in Cell Host Microbe (2019) Vol.13 pp367-376
NBS1 promotes the endonuclease activity of the MRE11-RAD50 complex by sensing CtIP phosphorylation
Anand, R. Jasrotia, A. Bundschuh, D. Ranjha, L. Stucki, M. Cejka, P.
in EMBO J (2019) Vol.38 ppe101005
Two-Photon Intravital Imaging of Leukocytes in the Trachea During Pneumococcal Infection
Palomino-Segura, M. Gonzalez, S. F.
in Methods Mol Biol (2019) Vol.1968 pp183-194
Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion
Walls, A. C. Xiong, X. Park, Y. J. Snijder, J. Quispe, J. Cameroni, E. Gopal, R. Dai, M. Lanzavecchia, A. Zambon, M. Rey, F. A. Corti, D. Veesler, D.
in Cell (2019) Vol.176 pp1026-1039
The contribution of active and passive mechanisms of 5mC and 5hmC removal in human T lymphocytes is differentiation- and activation-dependent
Vincenzetti, L. Leoni, C. Chirichella, M. Monticelli, S.
in Eur J Immunol (2019) Vol.49 pp611-625
P2X7 receptor restrains pathogenic Tfh cell generation in systemic lupus erythematosus
Faliti, C. E. Gualtierotti, R. Rottoli, E. Perruzza, L. Romagnani, A. Pellegrini, G. De Ponte Conti, B. Rossi, R. L. Idzko, M. Mazza, E. M. C. Bicciato, S. Traggiai, E. Meroni, P. L. Grassi, F.
in J Exp Med (2019) Vol.216 pp317-336
ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens
Proietti, M. Perruzza, L. Scribano, D. D'Antuono, R. Strati, F. Raffaelli, M. Gonzalez, S. F. Thelen, M. Hardt, W. D. Slack, E. Nicoletti, M. Grassi, F.
in Nat Commun (2019) Vol.10 pp250
Engineering polymeric nanocapsules for an efficient drainage and biodistribution in the lymphatic system
Cordeiro, A. S. Crecente-Campo, J. Lopez-Bouzo, B. Gonzalez, S. F. de la Fuente, M. Alonso, M. J.
in J Drug Target (2019) Vol. pp1-52
A selective ER-phagy exerts procollagen quality control via a Calnexin-FAM134B complex
Forrester, A. De Leonibus, C. Grumati, P. Piemontese, M. Staiano, L. Fregno, I. Raimondi, A. Marazza, A. Bruno, G. Iavazzo, M. Intartaglia, D. Seczynska, M. van Anken, E. Conte, I. De Matteis, M. A. Dikic, I. Molinari, M. Settembre, C.
in EMBO J (2019) Vol.38 ppe99847
The Antibody Response to Plasmodium falciparum: Cues for Vaccine Design and the Discovery of Receptor-Based Antibodies
Tan, J. Piccoli, L. Lanzavecchia, A.
in Annu Rev Immunol (2018) Vol.37 pp225-246
Detection and kinetics of persistent neutralizing anti-interferon-beta antibodies in patients with multiple sclerosis. Results from the ABIRISK prospective cohort study
Jensen, P. E. H. Warnke, C. Ingenhoven, K. Gasis, M. Hermanrud, C. Fernandez-Rodriguez, B. M. Ryner, M. Kramer, D. Link, J. Ramanujam, R. Auer, M. Buck, D. Grummel, V. Bertotti, E. Fissolo, N. Oliver-Martos, B. Nytrova, P. Khalil, M. Guger, M. Rathmaier, S. Sievers-Stober, C. Lindberg, R. L. P. Hassler, S. Bachelet, D. Aktas, O. Donnellan, N. Lawton, A. Hemmer, B. Havrdova, E. K.
in J Neuroimmunol (2018) Vol.326 pp19-27

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