Publications Archive

Label-Free Biosensor Detection of Endocrine Disrupting Compounds Using Engineered Estrogen Receptors
La Spina, R. Ferrero, V. E. V. Aiello, V. Varani, L. Lettieri, T. Calzolai, L. Haasnoot, W. Colpo, P.
in Biosensors (Basel) (2017) Vol.8 pp
Immune stealth-driven O2 serotype prevalence and potential for therapeutic antibodies against multidrug resistant Klebsiella pneumoniae
Pennini, M. E. De Marco, A. Pelletier, M. Cvitkovic, R. Beltramello, M. Cameroni, E. Bianchi, S. Zatta, F. Zhao, W. Xiao, X. Camara, M. M. DiGiandomenico, A. Semenova, E. Lanzavecchia, A. Warrener, P. Suzich, J. Wang, Q. Corti, D. Stover, C. K.
in Nat Commun (2017) Vol.8 pp1991
TRPM7 kinase activity is essential for T cell colonization and alloreactivity in the gut
Romagnani, A. Vettore, V. Rezzonico-Jost, T. Rottoli, E. Nadolni, W. Perotti, M. Meier, M. A. Hermanns, C. Geiger, S. Wennemuth, G. Recordati, C. Matsushita, M. Muehlich, S. Proietti, M. Chubanov, V. Gudermann, T. Grassi, F. Zierler, S.
in Nat Commun (2017) Vol.8 pp1917
Physiological protein blocks direct the Mre11-Rad50-Xrs2 and Sae2 nuclease complex to initiate DNA end resection
Reginato, G. Cannavo, E. Cejka, P.
in Genes Dev (2017) Vol.31 pp2325-2330
Epigenetic and transcriptional control of mast cell responses
Monticelli, S. Leoni, C.
in F1000Res (2017) Vol.6 pp2064
Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expression in multiple sclerosis
Hu, D. Notarbartolo, S. Croonenborghs, T. Cialic, R. Yang, T. H. Aschenbrenner, D. Andersson, K. M. Gattorno, M. Pham, M. Kivisakk, P. Pierre, I. V. Lee, Y. Kiani, K. Bokarewa, M. Tjon, E. Pochet, N. Sallusto, F. Kuchroo, V. K. Weiner, H. L.
in Nat Commun (2017) Vol.8 pp1600
Molecular Signatures of Immunity and Immunogenicity in Infection and Vaccination
Haks, M. C. Bottazzi, B. Cecchinato, V. Del Giudice, G. Kaufmann, S. H. E. Lanzavecchia, A. Lewis, D. J. M. Maertzdorf, J. Mantovani, A. Sallusto, F. Sironi, M. Uguccioni, M. Ottenhoff, T. H. M.
in Front Immunol (2017) Vol.8 pp1563
Phenotype and specificity of T cells in primary human cytomegalovirus infection during pregnancy: IL-7Rpos long-term memory phenotype is associated with protection from vertical transmission
Mele, F. Fornara, C. Jarrossay, D. Arossa, A. Spinillo, A. Lanzavecchia, A. Gerna, G. Sallusto, F. Lilleri, D.
in PLoS One (2017) Vol.12 ppe0187731
Adjuvants and the vaccine response to the DS-Cav1-stabilized fusion glycoprotein of respiratory syncytial virus
Sastry, M. Zhang, B. Chen, M. Kong, W. P. Chuang, G. Y. Ko, K. Kumar, A. Silacci, C. Thom, M. Salazar, A. M. Corti, D. Lanzavecchia, A. Taylor, G. Mascola, J. R. Graham, B. S. Kwong, P. D.
in PLoS One (2017) Vol.12 ppe0186854
Biochemistry: Complex assistance for DNA invasion
Cejka, P.
in Nature (2017) Vol.550 pp342-343
Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers
Taglialatela, A. Alvarez, S. Leuzzi, G. Ranjha, L. Huang, J. W. Madubata, C. Anand, R. Levy, B. Rabadan, R. Cejka, P. Costanzo, V. Ciccia, A.
in Mol Cell (2017) Vol.68 pp414-430 e8
Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2alpha Scaffolding Function
Gulluni, F. Martini, M. De Santis, M. C. Ghigo, A. Margaria, J. P. Ciraolo, E. Franco, I. Ala, U. Annaratone, L. Disalvatore, D. Bertalot, G. Viale, G. Noatynska, A. Compagno, M. Sigismund, S. Montemurro, F. Thelen, M. Fan, F. Meraldi, P. Marchio, C. Pece, S. Sapino, A. Chiarle, R. Di Fiore, P. P. Hirsch, E.
in Cancer Cell (2017) Vol.32 pp444-459 e7
The Atypical Receptor CCRL2 (C-C Chemokine Receptor-Like 2) Does Not Act As a Decoy Receptor in Endothelial Cells
Mazzotti, C. Gagliostro, V. Bosisio, D. Tiberio, L. Thelen, M. Sozzani, S.
in Front Immunol (2017) Vol.8 pp1233
A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential
Wang, J. Bardelli, M. Espinosa, D. A. Pedotti, M. Ng, T. S. Bianchi, S. Simonelli, L. Lim, E. X. Y. Foglierini, M. Zatta, F. Jaconi, S. Beltramello, M. Cameroni, E. Fibriansah, G. Shi, J. Barca, T. Pagani, I. Rubio, A. Broccoli, V. Vicenzi, E. Graham, V. Pullan, S. Dowall, S. Hewson, R. Jurt, S. Zerbe, O. Stettler, K. Lanzavecchia, A. Sallusto, F. Cavalli, A. Harris, E. Lok, S. M. Varani, L. Corti, D.
in Cell (2017) Vol.171 pp229-241 e15
Epicutaneous allergen application preferentially boosts specific T cell responses in sensitized patients
Campana, R. Moritz, K. Neubauer, A. Henning, R. Brodie, T. M. Kaider, A. Sallusto, F. Wohrl, S. Valenta, R.
in Sci Rep (2017) Vol.7 pp11657
Role of B cells in T helper cell responses in a mouse model of asthma
Wypych, T. P. Marzi, R. Wu, G. F. Sallusto, F.
in J Allergy Clin Immunol (2017) Vol.141 pp1395-1410
ALCAM (CD166) is involved in extravasation of monocytes rather than T cells across the blood-brain barrier
Lyck, R. Lecuyer, M. A. Abadier, M. Matti, C. Rosito, M. Enzmann, G. Zeis, T. Michel, L. Garcia Martin, A. B. Sallusto, F. Gosselet, F. Deutsch, U. Weiner, J. A. Schaeren-Wiemers, N. Prat, A. Engelhardt, B.
in J Cereb Blood Flow Metab (2017) Vol.37 pp2894-2909
Public antibodies to malaria antigens generated by two LAIR1 insertion modalities
Pieper, K. Tan, J. Piccoli, L. Foglierini, M. Barbieri, S. Chen, Y. Silacci-Fregni, C. Wolf, T. Jarrossay, D. Anderle, M. Abdi, A. Ndungu, F. M. Doumbo, O. K. Traore, B. Tran, T. M. Jongo, S. Zenklusen, I. Crompton, P. D. Daubenberger, C. Bull, P. C. Sallusto, F. Lanzavecchia, A.
in Nature (2017) Vol.548 pp597-601
* Pieper K., Tan J., Piccoli, L. contributed equally to this work.
SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination
Daddacha, W. Koyen, A. E. Bastien, A. J. Dhere, V. R. Nabeta, G. N. Connolly, E. C. Werner, E. Madden, M. Z. Daly, M. B. Minten, E. V. Whelan, D. R. Schlafstein, A. J. Zhang, H. Anand, R. Doronio, C. Withers, A. E. Shepard, C. Sundaram, R. K. Deng, X. Dynan, W. S. Wang, Y. Bindra, R. S. Cejka, P. Rothenberg, E. Doetsch, P. W. Kim, B. Yu, D. S.
in Cell Rep (2017) Vol.20 pp1921-1935
PPARgamma in dendritic cells and T cells drives pathogenic type-2 effector responses in lung inflammation
Nobs, S. P. Natali, S. Pohlmeier, L. Schneider, C. Kurrer, M. Sallusto, F. Kopf, M.
in J Exp Med (2017) Vol.214 pp3015-3035
Plasma cell deficiency in human subjects with heterozygous mutations in Sec61 translocon alpha 1 subunit (SEC61A1)
Schubert, D. Klein, M. C. Hassdenteufel, S. Yang, L. Proietti, M. Bulashevska, A. Kemming, J. Kuhn, J. Winzer, S. Rusch, S. Fliegauf, M. Schaffer, A. A. Pfeffer, S. Geiger, R. Cavalie, A. Cao, H. Yang, F. Li, Y. Rizzi, M. Eibel, H. Kobbe, R. Marks, A. L. Peppers, B. P. Hostoffer, R. W. Puck, J. M. Zimmermann, R. Grimbacher, B.
in J Allergy Clin Immunol (2017) Vol.141 pp1427-1438
The Tim-3-galectin-9 Secretory Pathway is Involved in the Immune Escape of Human Acute Myeloid Leukemia Cells
Goncalves Silva, I. Yasinska, I. M. Sakhnevych, S. S. Wellbrock, J. Bardelli, M. Varani, L. Hussain, R. Siligardi, G. Ceccone, G. Berger, S. M. Ushkaryov, Y. A. Gibbs, B. F. Fasler-Kan, E. Sumbayev, V. V.
in EBioMedicine (2017) Vol. pp44-57
Rituximab in multiple sclerosis: Frequency and clinical relevance of anti-drug antibodies
Dunn, N. Juto, A. Ryner, M. Piccoli, L. Fink, K. Piehl, F. Fogdell-Hahn, A.
in Mult Scler (2017) Vol. pp1352458517720044
ACKR3 expression on diffuse large B cell lymphoma is required for tumor spreading and tissue infiltration
Puddinu, V. Casella, S. Radice, E. Dirnhofer, S. Bertoni, F. Thelen, M.
in Oncotarget (2017) Vol.8 pp85068-85084
Immunological phenotype of the murine Lrba knockout
Gamez-Diaz, L. Neumann, J. Jager, F. Felber, F. Soulas-Sprauel, P. Perruzza, L. Grassi, F. Kogl, T. Aichele, P. Kilimann, M. Grimbacher, B. Jung, S.
in Immunol Cell Biol (2017) Vol.95 pp789-802
Epithelial-Mesenchymal transition in cancer metastasis through the lymphatic system
Karlsson, M. C. Gonzalez, S. F. Welin, J.
in Mol Oncol (2017) Vol.11 pp781-791
Mitochondrial dysfunction induced by a SH2 domain-targeting STAT3 inhibitor leads to metabolic synthetic lethality in cancer cells
Genini, D. Brambilla, L. Laurini, E. Civenni, G. Pandit, S. D'Antuono, R. Perez, L. Levy, D. E. Pricl, S. Carbone, G. M. Catapano, C. V.
in Proc Natl Acad Sci U S A (2017) Vol.114 ppE4924-E4933
Transcriptional determination and functional specificity of myeloid cells: making sense of diversity
Monticelli, S. Natoli, G.
in Nat Rev Immunol (2017) Vol.17 pp595-607
CXCL12alpha/SDF-1 from perisynaptic Schwann cells promotes regeneration of injured motor axon terminals
Negro, S. Lessi, F. Duregotti, E. La Ferla, M. Franceschi, S. Menicagli, M. Bergamin, E. Radice, E. Thelen, M. Megighian, A. Pirazzini, M. Mazzanti, C. M. Rigoni, M. Montecucco, C.
in EMBO Mol Med (2017) Vol.9 pp1000-1010
Tackling influenza with broadly neutralizing antibodies
Corti, D. Cameroni, E. Guarino, B. Zhu, Q. Lanzavecchia, A.
in Curr Opin Virol (2017) Vol.24 pp60-69
Regulation of PfEMP1-VAR2CSA translation by a Plasmodium translation-enhancing factor
Chan, S. Frasch, A. Mandava, C. S. Quintana, M. D. P. Vesterlund, M. Ghorbal, M. Joannin, N. Franzen, O. Lopez-Rubio, J. J. Barbieri, S. Lanzavecchia, A. Sanyal, S. Wahlgren, M.
in Nat Microbiol (2017) Vol.2 pp17068
Balance of Anti-CD123 Chimeric Antigen Receptor Binding Affinity and Density for the Targeting of Acute Myeloid Leukemia
Arcangeli, S. Rotiroti, M. C. Bardelli, M. Magnani, C. F. Biondi, A. Biagi, E. Tettamanti, S. Varani, L.
in Mol Ther (2017) Vol.25 pp1933-1945
Single or Multiple Access Channels to the CYP450s Active Site? an Answer from Free Energy Simulations of the Human Aromatase Enzyme
Magistrato, A. Sgrignani, J. Krause, R. Cavalli, A.
in J Phys Chem Lett (2017) Vol.8 pp2036-2042
High-avidity IgA protects the intestine by enchaining growing bacteria
Moor, K. Diard, M. Sellin, M. E. Wotzka, S. Y. Toska, A. Bakkeren, E. Arnoldini, M. Bansept, F. Co, A. D. Voller, T. Minola, A. Fernandez-Rodriguez, B. Agatic, G. Barbieri, S. Piccoli, L. Casiraghi, C. Corti, D. Lanzavecchia, A. Regoes, R. R. Loverdo, C. Stocker, R. Brumley, D. R. Hardt, W. D. Slack, E.
in Nature (2017) Vol.544 pp498-502
Editorial: Regulation of Inflammation, Its Resolution and Therapeutic Targeting
Uguccioni, M. Teixeira, M. M. Locati, M.
in Front Immunol (2017) Vol.8 pp415
Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4
Collins, P. J. McCully, M. L. Martinez-Munoz, L. Wheeldon, J. Caucheteux, S. Thelen, S. Cecchinato, V. Laufer, J. M. Purvanov, V. Monneau, Y. R. Lortat-Jacob, H. Legler, D. F. Uguccioni, M. Thelen, M. Piguet, V. Mellado, M. Moser, B.
in FASEB J (2017) Vol.31 pp3084-3097
Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation
Ziarek, J. J. Kleist, A. B. London, N. Montpas, N. Bonneterre, J. St-Onge, G. DiCosmo-Ponticello, C. J. Koplinski, C. A. Roy, I. Stephens, B. Thelen, S. Veldkamp, C. T. Coffman, F. D. Cohen, M. C. Dwinell, M. B. Thelen, M. Peterson, F. C. Heveker, N. Volkman, B. F.
in Sci Signal (2017) Vol.10 ppeaah5756
Activin-A co-opts IRF4 and AhR signaling to induce human regulatory T cells that restrain asthmatic responses
Tousa, S. Semitekolou, M. Morianos, I. Trochoutsou, A. I. Brodie, T. M. Poulos, N. Samitas, K. Kapasa, M. Konstantopoulos, D. Paraskevopoulos, G. Gaga, M. Hawrylowicz, C. M. Sallusto, F. Xanthou, G.
in Proc Natl Acad Sci U S A (2017) Vol.114 ppE2891-E2900
T Follicular Helper Cells Promote a Beneficial Gut Ecosystem for Host Metabolic Homeostasis by Sensing Microbiota-Derived Extracellular ATP
Perruzza, L. Gargari, G. Proietti, M. D'Erchia, A. M. Faliti, C. E. Rezzonico-Jost, T. Scribano, D. Mauri, L. Colombo, D. Pellegrini, G. Moregola, A. Mooser, C. Pesole, G. Nicoletti, M. Norata, G. D. Geuking, M. B. McCoy, K. D. Guglielmetti, S. Grassi, F.
in Cell Rep (2017) Vol.18 pp2566-2575
Protection of calves by a prefusion-stabilized bovine RSV F vaccine
Zhang, B. Chen, L. Silacci Fregni, C. Boyington, J. C. Druz, A. Joyce, M. G. Guzman, E. Kong, W. P. Lai, Y. T. Stewart-Jones, G. B. E. Tsybovsky, Y. Yang, Y. Zhou, T. Baxa, U. Mascola, J. R. Corti, D. Lanzavecchia, A. Taylor, G. Kwong, P. D.
in npj Vaccines (2017) Vol.2 pp7
Macrophage Death following Influenza Vaccination Initiates the Inflammatory Response that Promotes Dendritic Cell Function in the Draining Lymph Node
Chatziandreou, N. Farsakoglu, Y. Palomino-Segura, M. Pizzagalli, D. U. Sallusto, F. Lukacs-Kornek, V. Uguccioni, M. Corti, D. Turley, S. J. Lanzavecchia, A. Carroll, M. C. Gonzalez, S. F.
in Cell Rep (2017) Vol.18 pp2427-2440
Social network architecture of human immune cells unveiled by quantitative proteomics
Rieckmann, J. C. Geiger, R. Hornburg, D. Kveler, K. Jarrossay, D. Sallusto, F. Shen-Orr, S. S. Lanzavecchia, A. Mann, M. Meissner, F.
in Nat Immunol (2017) Vol.18 pp583-593
The motor activity of DNA2 functions as an ssDNA translocase to promote DNA end resection
Levikova, M. Pinto, C. Cejka, P.
in Genes Dev (2017) Vol.31 pp493-502
Dnmt3a restrains mast cell inflammatory responses
Leoni, C. Montagner, S. Rinaldi, A. Polletti, S. Balestrieri, C. Monticelli, S.
in Proc Natl Acad Sci U S A (2017) Vol.114 ppE1490-E1499
Commented in Science (PMID: 28232567 )
Role of SEC62 in ER maintenance: A link with ER stress tolerance in SEC62-overexpressing tumors?
Bergmann, T. J. Fumagalli, F. Loi, M., Molinari, M.
in Mol Cell Oncol (2017) Vol.4 ppe1264351
Dynamic intravital imaging of cell-cell interactions in the lymph node
Stein, J. V. Gonzalez, S. F.
in J Allergy Clin Immunol (2017) Vol.139 pp12-20
Modulation of chemokine receptor function by cholesterol: new prospects for pharmacological intervention
Legler, D. F. Matti, C. Laufer, J. M. Purvanov, V. Uetz-von Allmen, E. Thelen, M.
in Mol Pharmacol (2017) Vol.91 pp331-338
The Mre11-Nbs1 Interface Is Essential for Viability and Tumor Suppression
Kim, J. H. Grosbart, M. Anand, R. Cejka, P. Petrini, J. H.
in Cell Rep (2017) Vol.18 pp496-507
Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization
Cecchinato, V. Bernasconi, E. Speck, R. F. Sauermann, U. D'Agostino, G. Danelon, G. Rezzonico Jost, T. Grassi, F. Raeli, L. Schoni-Affolter, F. Stahl-Hennig, C. Uguccioni, M. Swiss, H. I. V. Cohort Study
in J Immunol (2016) Vol.198 pp184-195
Approaches to Detect microRNA Expression in T Cell Subsets and T Cell Differentiation
Monticelli, S. Aijo, T. Trifari, S.
in Methods Mol Biol (2016) Vol.1514 pp153-172

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