Publications Archive

Antibody Binding Modulates Conformational Exchange in Domain III of Dengue Virus E Protein
Moraes, A. H. Simonelli, L. Pedotti, M. Varani, L. Valente, A. P.
in J Virol (2015) Vol.90 pp1802-11
* Luca Varani is co-corresponding author
Unraveling the Efficacy and Safety Profiles of Anti-CD123 Chimeric Antigen Receptors (CARs) in a Model of Acute Myeloid Leukemia Immunotherapy By Investigating CAR Binding Affinity and Density Variables
Arcangeli, S. Bardelli, M. Tettamanti, S. Simonelli, L. Magnani, C. F. Varani, V. Biondi, A. Biagi, E.
in 57th ASH Annual Meeting (2015) Vol.126 pp1359
Allosteric Modulation of Alpha7 Nicotinic Receptors: Mechanistic Insight through Metadynamics and Essential Dynamics
Grazioso, G. Sgrignani, J. Capelli, R. Dallanoce, C. De Amici, M. Cavalli, A.
in J Chem Inf Model (2015) Vol.55 pp2528-39
A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
Menachery, V. D. Yount, B. L., Jr. Debbink, K. Gralinski, L. E. Plante, J. A. Graham, R. L. Scobey, T. Ge, X. Y. Donaldson, E. F. Randell, S. H. Lanzavecchia, A. Marasco, W. A. Shi, Z. L. Baric, R. S.
in Nat Med (2015) Vol.21 pp1508-13
Vineet D Menachery and Ralph Baric are co-corresponding authors.
Bayesian inference of protein ensembles from SAXS data
Antonov, L. D. Olsson, S. Boomsma, W.
in Phys Chem Chem Phys (2015) Vol.18 pp5832-8
Enhancement of Muscle T Regulatory Cells and Improvement of Muscular Dystrophic Process in mdx Mice by Blockade of Extracellular ATP/P2X Axis
Gazzerro, E. Baldassari, S. Assereto, S. Pistorio, A. Panicucci, C. Volpi, S. Perruzza, L. Fiorillo, C. Minetti, C. Traggiai, E. Grassi, F. Bruno, C.
in Am J Pathol (2015) Vol.185 pp3349-60
Epigenetics of T lymphocytes in health and disease
Leoni, C. Vincenzetti, L. Emming, S.
in Swiss Med Wkly (2015) Vol.145 ppw14191
Full Text
Antigen-Specific Th17 Cells Are Primed by Distinct and Complementary Dendritic Cell Subsets in Oropharyngeal Candidiasis
Trautwein-Weidner, K. Gladiator, A. Kirchner, F. R. Rulicke, T. Sallusto, F. LeibundGut-Landmann, S.
in PLoS Pathog (2015) Vol.11 ppe1005164
Somatic mutations and affinity maturation are impaired by excessive numbers of T follicular helper cells and restored by Treg cells or memory T cells
Preite, S. Baumjohann, D. Foglierini, M. Ronchi, F. Rodriguez, B. M. Corti, D. Lanzavecchia, A. Sallusto, F.
in Eur J Immunol (2015) Vol.45 pp3010-21
Complementarity and congruence between exact NOEs and traditional NMR probes for spatial decoding of protein dynamics
Vogeli, B. Olsson, S. Riek, R.
in J Struct Biol (2015) Vol.191 pp306-17
Differential expression and biochemical activity of the immune receptor Tim-3 in healthy and malignant human myeloid cells
Goncalves Silva, I. Gibbs, B. F. Bardelli, M. Sumbayev, V. V.
in Oncotarget (2015) Vol.6 pp33823-33
* Co-corresponding author
Molecular Determinants for Unphosphorylated STAT3 Dimerization Determined by Integrative Modeling
Sgrignani, J. Olsson, S. Ekonomiuk, D. Krause, R. Catapano, C. V. Cavalli, A.
in Biochemistry (2015) Vol.54 pp5489-501
Quantification of Entropy-Loss in Replica-Averaged Modeling
Olsson, S. Cavalli, A.
in J Chem Theory Comput (2015) Vol.11 pp3973-7
Division of labor among oxidoreductases: TMX1 preferentially acts on transmembrane polypeptides
Pisoni, G. B. Ruddock, L. W. Bulleid, N., Molinari, M.
in Mol Biol Cell (2015) Vol.26 pp3390-400
Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus
Corti, D. Zhao, J. Pedotti, M. Agnihothram, S. Fett, C. Fernandez-Rodriguez, B. Foglierini, M. Agatic, G. Vanzetta, F. Gopal, R. Langrish, C. J. Barrett, N. A. Sallusto, F. Baric, R. S. Varani, L. Zambon, M. Perlman, S. Lanzavecchia, A.
in Proc Natl Acad Sci U S A (2015) Vol.112 pp10473-8
D.C. and J.Z. contributed equally to this work.
Structures of complexes formed by H5 influenza hemagglutinin with a potent broadly neutralizing human monoclonal antibody
Xiong, X. Corti, D. Liu, J. Foglierini, M. Calder, L. J. Martin, S. R. Lin, Y. P. Walker, P. A. Collins, P. J. Monne, I. Suguitan, A. L., Jr. Santos, C. Temperton, N. J. Subbarao, K. Lanzavecchia, A. Gamblin, S. J. Skehel, J. J.
in Proc Natl Acad Sci U S A (2015) Vol.112 pp9430-5
X.X., D.C., and J.L. contributed equally to this work.
The Protein-disulfide Isomerase ERp57 Regulates the Steady-state Levels of the Prion Protein
Torres, M. Medinas, D. B. Matamala, J. M. Cornejo, V. H. Solda, T. Andreu, C. Rozas, P. Matus, S. Munoz, N. Vergara, C. Cartier, L. Soto, C. Molinari, M. Hetz, C.
in J Biol Chem (2015) Vol.290 pp23631-45
IMMUNODEFICIENCIES. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations
Okada, S. Markle, J. G. Deenick, E. K. Averbuch, D. Lagos, M. Alzahrani, M. Al-Muhsen, S. Halwani, R. Ma, C. S. Wong, N. Soudais, C. Henderson, L. A. Marzouqa, H. Shamma, J. Gonzalez, M. Martinez-Barricarte, R. Okada, C. Avery, D. T. Latorre, D. Deswarte, C. Jabot-Hanin, F. Torrado, E. Fountain, J. Belkadi, A. Itan, Y. Boisson, B. Migaud, M. Arlehamn, C. S. Sette, A.
in Science (2015) Vol.349 pp606-13
Serum Immunoglobulin A Cross-Strain Blockade of Human Noroviruses
Lindesmith, L. C. Beltramello, M. Swanstrom, J. Corti, D. Lanzavecchia, A. Baric, R. S.
in Open Forum Infect Dis (2015) Vol.2 ppofv084
Neutralization and clearance of GM-CSF by autoantibodies in pulmonary alveolar proteinosis
Piccoli, L. Campo, I. Fregni, C. S. Minola, A. Sallusto, F. Luisetti, M. Corti, D. Lanzavecchia, A.
in Nat Commun (2015) Vol.6 pp7375
Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution
Brewer, K. D. Bacaj, T. Cavalli, A. Swarbrick, J. D. Liu, J. Zhou, A. Zhou, P. Barlow, N. Xu, J. Seven, A. B. Prinslow, E. A. Voleti, R. Haussinger, D. Bonvin, A. M. Tomchick, D. R. Vendruscolo, M. Graham, B. Sudhof, T. C. Rizo, J.
in Nat Struct Mol Biol (2015) Vol.22 pp555-64
Glycoprotein maturation and quality control
Molinari, M. Hebert, D. N.
in Semin Cell Dev Biol (2015) Vol.41 pp70
QM/MM MD Simulations on the Enzymatic Pathway of the Human Flap Endonuclease (hFEN1) Elucidating Common Cleavage Pathways to RNase H Enzymes
Sgrignani, J. Magistrato, A.
in ACS Catal. (2015) Vol.5 pp3864-3875
Analysis of the performance of the CHESHIRE and YAPP methods at CASD-NMR round 3
* Cavalli, A. Vendruscolo, M.
in J Biomol NMR (2015) Vol.62 pp503-9
* Co-corresponding author
Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors
Zhou, T. Lynch, R. M. Chen, L. Wu, X. Doria-Rose, N. A. Joyce, M. G. Lingwood, D. Soto, C. Bailer, R. T. Ernandes, M. J. Kong, R. Longo, N. S. Louder, M. K. McKee, K. O'Dell, S. Schmidt, S. D. Tran, L. Yang, Z. Druz, A. Luongo, T. S. Moquin, S. Srivatsan, S. Yang, Y. Zhang, B. Zheng, A. Pancera, M. Kirys, T. Georgiev, I. S. Gindin, T.
in Cell (2015) Vol.161 pp1280-92
John R. Mascola, Peter D. Kwong are co-corresponding authors.
An atypical addition to the chemokine receptor nomenclature: IUPHAR Review 15
Bachelerie, F. Graham, G. J. Locati, M. Murphy, P. M. Nibbs, R. Rot, A. Sozzani, S. Thelen, M.
in Br J Pharmacol (2015) Vol.172 pp3945-9
Molecular Dynamics of Biomolecules through Direct Analysis of Dipolar Couplings
Olsson, S. Ekonomiuk, D. Sgrignani, J. Cavalli, A.
in J Am Chem Soc (2015) Vol.137 pp6270-8
ERK phosphorylation and miR-181a expression modulate activation of human memory TH17 cells
Mele, F. Basso, C. Leoni, C. Becattini, S. Latorre, D. Lanzavecchia, A. Sallusto, F. Monticelli, S.
in Nat Commun (2015) Vol.6 pp6431
Federica Sallusto and Silvia Monticelli equally contributed to this work and are co-corresponding authors.
Reduced DNA methylation and hydroxymethylation in patients with systemic mastocytosis
Leoni, C. Montagner, S. Deho, L. De Matteis, G. Marzano, A. V. Merante, S. Orlandi, E. M. Zanotti, R. Monticelli, S.
in Eur J Haematol (2015) Vol.95 pp566-75
Hitting the right spot: Mechanism of action of OPB-31121, a novel and potent inhibitor of the Signal Transducer and Activator of Transcription 3 (STAT3)
Brambilla, L. Genini, D. Laurini, E. Perez, L. Fermeglia, M. Carbone, G. M. Pricl, S. Catapano, C. V.
in Mol Oncol (2015) Vol.9 pp1194-206
Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and systemic IgG1 mAbs: Complete protection of rhesus monkeys from mucosal SHIV challenge
Sholukh, A. M. Watkins, J. D. Vyas, H. K. Lakhashe, S. K. Thorat, S. Zhou, M. Hemashettar, G. Bachler, B. C. Forthal, D. N. Villinger, F. Sattentau, Q. J. Weiss, R. A. Agatic, G. Corti, D. Lanzavecchia, A. Heeney, J. L. Ruprecht, R. M.
in Vaccine (2015) Vol.33 pp2086-95
Epitope mapping by solution NMR spectroscopy
Bardelli, M. Livoti, E. Simonelli, L. Moraes, A. Valente, A. P. Varani, L.
in J Mol Recognit (2015) Vol.28 pp393-400
* Luca Varani is co-corresponding author
Rationally Modified Estrogen Receptor Protein as a Bio-Recognition Element for the Detection of EDC Pollutants: Strategies and Opportunities
Pedotti, M. Ferrero, V. E. Lettieri, T. Follonier, S. Calzolai, L. Varani, L.
in Int J Environ Res Public Health (2015) Vol.12 pp2612-21
A novel UGGT1 and p97-dependent checkpoint for native ectodomains with ionizable intramembrane residue
Merulla, J. Solda, T. Molinari, M.
in Mol Biol Cell (2015) Vol.26 pp1532-42
* Recommended by the Faculty of 1000
Insights into the coiled-coil organization of the Hendra virus phosphoprotein from combined biochemical and SAXS studies
Beltrandi, M. Blocquel, D. Erales, J. * Cavalli, A. Longhi, S.
in Virology (2015) Vol.477 pp42-55
* Co-corresponding author
Herpes simplex virus enhances chemokine function through modulation of receptor trafficking and oligomerization
Martinez-Martin, N. Viejo-Borbolla, A. Martin, R. Benovic, J. L. Thelen, M. Alcami, A.
in Nat Commun (2015) Vol.6 pp6163
T cell immunity. Functional heterogeneity of human memory CD4(+) T cell clones primed by pathogens or vaccines
Becattini, S. Latorre, D. Mele, F. De Gregorio, C. Cassotta, A. Fernandez, B. Kelderman, S. Schumacher, T. N. Corti, D. Lanzavecchia, A. Sallusto, F.
in Science (2014) Vol.347 pp400-6
Abstract Reprint Full Text
Immunological consequences of intragenus conservation of Mycobacterium tuberculosis T-cell epitopes
Lindestam Arlehamn, C. S. Paul, S. Mele, F. Greenbaum, J. A. Vita, R. Sidney, J. Peters, B. Sallusto, F. Sette, A.
in Proc Natl Acad Sci U S A (2014) Vol.112 ppE147-55
N-linked sugar-regulated protein folding and quality control in the ER
Tannous, A. Pisoni, G. B. Hebert, D. N., Molinari, M.
in Semin Cell Dev Biol (2014) Vol.41 pp79-89

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