Institute for Research in Biomedicine
Bellinzona, January 28, 2026 On January 28–29, 2026, the Institute for Research in Biomedicine (IRB) in Bellinzona, affiliated with Università della Svizzera italiana (USI), will host the second edition of the Swiss Influenza Meeting, a biennial event bringing together leading Swiss researchers studying influenza in the fields of virology,
Published in Nature Communications, the work from the Cejka laboratory reveals how MutSβ-MutLγ-driven trinucleotide expansion arise in neural cells and how FAN1 safeguards the genome. This mechanism clarifies Huntington’s disease biology and points to therapeutic targets. Huntington’s disease is driven by the gradual expansion of CAG repeats in the
Image Caption: FCRL3 expression is sufficient to modulate T cell responses through the engagement with negative regulators of signaling (image by Elena Foli). A new study is published in the Journal of Experimental Medicine by the Molecular Immunology lab. This study characterizes the FCRL3 receptor as an immunoregulatory molecule
Homologous recombination (HR) could be deleterious when cells are about to undergo division. The Cejka laboratory at the IRB identified a new PLK1-mediated mechanism, which down-regulates DNA end resection late in the cell cycle and hence prevents undesirable HR initiation. Bellinzona, February 8, 2023 – DNA double-strand break (DSB)
Can one single antibody catch them all? Scientists discover antibodies that recognise all SARS-CoV-2 variants and also other coronaviruses that cause human disease. The finding opens the door to the development of novel countermeasures against present and future coronavirus threats. Bellinzona, January 27, 2023 – The coronavirus keeps evolving,
Melanoma is the most lethal skin cancer, and its incidence, though low, has steadily increased over the last few years. During melanoma progression, tumor cells spread across the body via the lymphatic system, a network of vessels and organs, called lymph nodes, which are part of the immune system.
Recent years have generated considerable demand for information and interaction between Science and society. In this sense, the open day organized in the new Bios+ building in Bellinzona by IRB, IOR and the EOC Laboratories allowed to foster dialogue between the world of Science and the public. On Saturday,
Secretory Immunoglobulin A (SIgA) is the antibody produced within mucosal membranes and is the most abundant antibody type synthesized in our body. In the intestine, SIgA possesses two antithetic functions acting either in preventing or promoting bacterial colonization. When the intestine is attacked by an invasive bacterium, a strongly
Ticino is becoming a biotech hub Greater Zurich Area April 1, 2021 Ricerca biomedica senza frontiere Ticino Management April, 2021 Immunoncologia, alleanza vincente Ticino Management May, 2021 Schierati con il sistema immunitario Ticino Management June, 2021 Ragione e sentimento Ticino Management, Scienza e salute Un laboratorio per la vita
The change at the helm of the Institute for Research in Biomedicine (IRB, affiliated to USI) has occurred at the end of July, with Prof. Antonio Lanzavecchia succeded by Prof. Davide Robbiani, who returns to Ticino after a brilliant career in the United States.1 The announcement was already made
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