New SNSF grants awarded to four IRB researchers

Bellinzona – June 11 2024 – The Swiss National Science Foundation (SNSF) has recently awarded SNSF grants to four researchers at the Institute for Research in Biomedicine (IRB, affiliated to Università della Svizzera italiana): Valentina Cecchinato, Greta Guarda, Maurizio Molinari, and Silvia Monticelli. Valentina Cecchinato, research associate hosted in the group of Mariagrazia Uguccioni, focuses […]

New study characterizes the role of selected RNA-binding proteins in immune cells

A new study was published in Life Science Alliance by the Monticelli lab. The study characterizes the role of RNA-binding proteins in modulating mast cell functions, and was spearheaded by Marian Bataclan and Cristina Leoni, in collaboration with the Heissmeyer lab (LMU Munich). Bellinzona, June 06, 2024 – Mast cells are crucial components of our […]

Comel Foundation supports IRB predoctoral program and a research project

Bellinzona – June 5, 2024 – The Institute for Research in Biomedicine (IRB, affiliated with the University of Italian Switzerland) is pleased to announce the support of the Comel Foundation for two important initiatives The first involves the creation of a predoctoral program, in which selected Swiss and international candidates receive a fellowship for up […]

New Study Reveals Alternative Pathways for Clearing Misfolded Proteins in Rare Diseases

Rare diseases like the deficiency of alpha1-antitrypsin or lysosomal storage disorders are caused by degradation of mutant proteins. In their latest study published in EMBO Reports, Elisa Fasana, Ilaria Fregno, Carmela Galli and Tatiana Soldà in the group led by Maurizio Molinari elucidate the pathways that ensure the clearance of misfolded proteins, when the major […]

Mechanism of DNA unwinding by MCM8-9 in complex with HROB

In a new study published in “Nature Communications” the Cejka laboratory and collaborators identified the molecular mechanisms by which the HROB protein enhances the DNA unwinding function of the MCM8-9 helicase, crucial for DNA repair and replication processes. Bellinzona, May 2, 2024 – The MCM8-9 helicase and the HROB proteins function together in DNA repair. […]

Bios+ Open Day

The Institute for Research in Biomedicine (IRB), the Institute of Oncology Research (IOR) and the laboratories for translational research of the EOC invite you to the open day that will take place on Saturday May 25th from 9:00 a.m. to 1:00 p.m at Bios+ (Via Francesco Chiesa 5, 6500 Bellinzona).  This is an opportunity to […]