EXO1 promotes the meiotic MLH1-MLH3 endonuclease through conserved interactions with MLH1, MSH4 and DNA

A paper published in the journal “Nature Communications” by the Cejka laboratory shows how EXO1, a nuclease known for its role in DNA end resection in homologous recombination and in DNA mismatch repair, has a nuclease-independent role to promote the nuclease activity of MLH1-MLH3 complex. Bellinzona – May 08 2025 – During meiosis – a […]
Expansion of Scientific Collaboration Agreement between IRB and Humanitas University

Since 2019 IRB and Humanitas University, located in Pieve Emanuele (Milan), have had agreements to facilitate joint scientific projects and student exchange. In 2024, this agreement was renewed and extended to include the Humanitas Hospital, an institution focused on excellence in clinical care and research. In particular, in future years it is intended to intensify […]
Development of broadly protective influenza virus vaccines
Prof. Florian Krammer Icahn School of Medicine at Mount Sinai, New York, NY Thursday, 10 April 2025 at 12 pm Bios+ Seminar Room
Scaling AI protein structure prediction to the virosphere
Prof. Joe Grove MRC-University of Glasgow, Centre for Virus Research Monday, 3 March 2025 at 4 pm Bios+ Seminar Room Contact: Prof. Davide Robbiani This event is supported by the IRB-Rockefeller University partnership for infectious disease research.
Castelgrande Lecture 2025

Vi informiamo che, la Castelgrande Lecture 2025 si terrà il prossimo martedì 30 settembre, alle ore 17.00, e si terrà presso la sala Bios+ in via F. Chiesa 5, Bellinzona. È confermata la presenza del Prof. Rino Rappuoli, Direttore Scientifico della Fondazione Biotecnopolo di Siena. L’evento, organizzato dall’associazione Bios+, si inserisce nei festeggiamenti per il 25° […]
2025 International Laboratory Animal Technician week
As part of the 2025 International Laboratory Animal Technician week, at the Institute for Research in Biomedicine (IRB) – together with IOR and LRT-EOC – the Culture of Care Working Group organized some initiatives to recognize the fundamental role of animal caretakers in supporting biomedical research. This annual celebration recognizes laboratory animal technicians for their […]
Meiotic chromosome movement: what’s the lamina got to do with it?
Prof. Verena Jantsch-Plunger Max Perutz Labs, University of Vienna Tuesday, 4 March 2025 at 12 pm Bios+ Seminar Room
Crossing the Species Barrier: How Animal Viruses Enter Human Cells
Prof. Rafael Sanjuan University of Valencia, Dept of Genetics Tuesday, 25 February 2025 at 4 pm Bios+ Seminar Room Contact: Prof. Davide Robbiani This event is supported by the IRB-Rockefeller University partnership for infectious disease research.
Malaria’s Secret Language: Decoding the Signaling Role of Extracellular Vesicles
Prof. Neta Regev-Rudzki Department of Biomolecular Sciences, Weizmann Institute of Science, Israel Tuesday, 18 February 2025, at 12 pm Bios+ Seminar Room
IRB celebrates its 25th anniversary

To symbolize this anniversary, the IRB chose the bamboo plant. Many features of the bamboo plant are reminiscent of the scientific process. Click Here to learn more.
