Stefan Emming awarded PhD
on April 15, 2019 Stefan Emming successfully defended his PhD thesis, which was presented at the University of Bern on April 11th, 2019. His thesis title was “Mechanisms of regulation of human T cell activation and GM-CSF production” and the study was performed in the Molecular Immunology lab headed by Dr. Silvia Monticelli at the Institute for Research […]
Rafet Ameti, Marisa Loi and Philipp Paparoditis IRB Student awardees 2018-2019
on April 11, 2019 During the annual IRB Student Retreat, which took place on April 8 – 10 in Weggis, Rafet Ameti (Signal Transduction Lab), Marisa Loi (Protein Folding and Quality Control Lab) and Philipp Paparoditis (Immune Regulation Lab) were announced as the grantees of the seventh IRB student award. This award is meant to […]
New paper from the Guarda Lab
on April 2, 2019 The phosphatase Shp-2 has been suggested to regulate signaling downstream of NK cell inhibitory receptors, which are essential to calibrate NK cell responsiveness; however, our genetic approaches did not support this hypothesis. Intriguingly, Shp-2 has been shown to positively regulate ERK (extracellular signal-regulated kinase) activation in various tissues. We thus investigated […]
9° giornata della Ricerca della Svizzera italiana – Best original publication 2018 over 35 and best talk awarded to Samuele Notarbartolo and Alessandro Marazza, respectively
on March 22, 2019 During the 9° giornata della Ricerca della Svizzera italiana, organized by the EOC Clinical Trial Unit and the Università della Svizzera italiana (USI), held at USI in Lugano on Friday March 15, 2019, a Postdoc and a PhD student affiliated to the Institute for Research in Biomedicine (IRB) were awarded for […]
Designed Protein-Nanoparticle Vaccine against Respiratory Syncytial Virus, a study from the Perez’s lab published in Cell
on March 7, 2019 A collaborative project between the Institute for Research in Biomedicine (IRB) affiliated to the Università della Svizzera italiana (USI), the Institute for Protein Design, Washington University, USA, the Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden and the Fred Hutchinson Cancer Research Center, Seattle, USA provides new hope for the development […]
Gianluca D’Agostino awarded PhD
on February 28, 2019 Gianluca D’Agostino successfully defended his PhD thesis, which was presented at the University of Fribourg (CH) on February 15th, 2019. His thesis title was “Dissection of the mechanisms regulating the CXCL12/HMGB1 heterocomplex-mediated chemotaxis in cancer cells, and in monocytes from Rheumatoid Arthritis patients” and the work has been done in the […]
New paper from the González Lab
on February 27, 2019 The role of natural killer (NK) cells in the immune response against vaccines is not fully understood. This study, published in Cell Reports, determined the function of infiltrated NK cells in the initiation of the inflammatory response triggered by inactivated influenza virus vaccine in the draining lymph node (LN). In this […]
Two publications from Cejka’s laboratory describe how cells repair broken DNA
on February 26, 2019 DNA bears all genetic information required for proper development and function of all living organisms. DNA molecule is however prone to breakage, threatening cell survival. Incorrect DNA break repair leads to mutations, which may drive tumorigenesis. In order to repair broken DNA without errors, cell utilize genetic information stored in the […]
New study by the Monticelli’s lab on epigenetic modifications in human T cells
on February 12, 2019 This study, performed primarily by Lucia Vincenzetti, was recently published in the European Journal of Immunology. Epigenetic modifications such as DNA methylation are crucial to the appropriate regulation of gene expression in T lymphocytes, ultimately influencing all aspects of T cell biology. This study determined the dynamics of modifications of cytosines […]
Pfizer Foundation Research Prize 2019 – accolades for researchers in Ticino
on February 7, 2019 This evening, at a ceremony held in Zurich, the Pfizer Foundation awarded two prizes to research groups at the Institute for Research in Biomedicine (IRB) and at the Institute of Oncology Research (IOR), both affiliated to Università della Svizzera italiana (USI Faculty of Biomedical Sciences). Dr. Greta Guarda and Dr. Sonia […]
