The transcription factor Bhlhe40 as a regulator of immunity
From: Associate Professor, Department of Pathology & Immunology, Washington University School of Medicine in St. Louis. Host contact: Silvia Monticelli Date: 14.01.2021 15:30 Speakers: Brian Edelson Virtual Conference
12th EADV-IRB Dermatological Web Meeting<br>Distinguished speakers with well-recognized experience will lead this 3-hour event
From: Distinguished speakers with well-recognized experience will lead this 3-hour event Date: 19.11.2020 16:00 – 19:15 Virtual Conference – Registration
Cellular and molecular trafficking in the regulation of inflammation in visceral organs
From: Department of Pathology & Immunology, Washington University School of Medicine in St. Louis, US Host contact: Davide Robbiani Date: 20.10.2020 15:00 Speakers: Gwendalyn (Gwen) Randolph Virtual Conference
The role of bacterial virulence factors in induction of intestinal mucosal immune responses
From: Head of the Gut Microbiology laboratory, Institute for Infectious Diseases, University of Bern, CH Host contact: Fabio Grassi Date: 13.10.2020 12:00 Speaker: Siegfried Hapfelmeier
Fibroblast causalities in chronic inflammation and cancer
From: Member of the Academy of Athens. Director, Department of Physiology, Medical School, University of Athens. Associate Researcher, Biomedical Sciences Research Center ‘Alexander Fleming’ Host contact: Santiago González Date: 6.11.2020 10:00 Speakers: George Kollias Virtual Conference
Regulation of the MLH1-MLH3 endonuclease in meiosis: a Nature paper by the Cejka Lab

When our DNA breaks, cells use the homologous recombination pathway to accurately repair the break, so that DNA is fixed and no mutations are introduced during the repair process. When multiple DNA molecules are broken, the recombination factors use a smart strategy to join only the DNA pieces originating from the same DNA molecules. This […]
Antonino Cassotta awarded PhD
Antonino Cassotta successfully defended his PhD thesis, which was presented at the Eidgenössische Technische Hochschule (ETH) Zurich on 6th February 2020. His thesis title was “Clonal selection and immunodominance in the human T cell response to microbial antigens and biologicals” and the study was conducted in the Cellular Immunology lab headed by Prof. Federica Sallusto […]
Marginal zone formation requires ACKR3 expression on B cells : a new paper by the Thelen Lab

The marginal zone (MZ) of the spleen contains a specialized set of innate-like B cells that are in direct contact with the blood. This study, published in Cell Reports, shows that expression of the atypical chemokine receptor 3 (ACKR3) defines two phenotypically, transcriptionally and functionally distinct, equal-sized populations of mouse MZ B cells (MZBs). The […]
Davide Robbiani takes office as new director of the IRB

The change at the helm of the Institute for Research in Biomedicine (IRB, affiliated to USI) has occurred at the end of July, with Prof. Antonio Lanzavecchia succeded by Prof. Davide Robbiani, who returns to Ticino after a brilliant career in the United States.1 The announcement was already made in June 2019, when the Foundation […]
New paper from the Grassi lab on Rejuvenating tumor-killing lymphocytes

Genetic alteration of an endogenous cell constitutes the initial trigger in tumor development. Prevention and chemotherapy have dramatically ameliorated the prognosis of many cancers. However, it has become clear that immunotherapeutic strategies can definitely contribute to the cure and possibly eradication of cancer. Within this therapeutic rationale, therapies with tumor specific chimeric antigen receptor (CAR) […]
