International Symposium, IRB, Sept 22-23, 2022: Typical and atypical research(er) on chemokines

Symposium Typical and atypical research(er) on chemokines Schedule of presentations (draft) Thursday 22.9.2022 9:30 – 9:45 Opening Marcus Thelen   Session 1 – Discussion leader: Marcus Thelen 9:45 – 10:15 Sergio Lira 10:15 – 10:20 Discussion 10:20 – 10:50 Michel Bouvier 10:50 – 10:55 Discussion 10:55 – 11:25 Break 11:25 – 11:55 Barbara Moepps 11:55 – 12:00 […]

Protein axis to promote genome stability

Bellinzona, March 4, 2022 – The Bloom’s syndrome helicase (BLM) functions in DNA double-strand break repair to prevent crossover recombination. In the absence of BLM, crossover recombination products are increased, leading to a loss of heterozygosity and dramatically increased incidence of cancers. Mechanistically, BLM helicase functions together with a TopoIIIa topoisomerase to process recombination products […]

CANCOL, a Computer-Assisted Annotation Tool to Facilitate Colocalization and Tracking of Immune Cells

Bellinzona, February 22, 2022 – Four-dimensional imaging data obtained via two-photon intravital microscopy (2P-IVM) are classically analyzed by performing automated cell tracking, a procedure that computes the trajectories followed by each cell. Artificial intelligence (AI) methods are crucial in this analysis process.  However, AI can generate detrimental results when applied in biomedical research without considering […]

Niccolò Bianchi awarded PhD

Niccolò Bianchi successfully defended his PhD thesis, which was presented at the University of Bern on December 16th, 2021. His thesis title was “Regulation of inflammatory phenotypes in human T helper lymphocytes” and the study was conducted in the Molecular Immunology lab headed by Dr. Silvia Monticelli at the Institute for Research in Biomedicine, in […]

New paper published in PLoS Biology

Bellinzona, February 15, 2022 – The proliferation and effector function of T lymphocytes of the immune system must be carefully regulated. These cells are indeed crucial sentinels that protect the body from invading pathogens, but their powerful responses must be limited in magnitude and duration to avoid damage to healthy tissues. A network of molecular […]

Giordano Reginato awarded PhD

Giordano Reginato successfully defended his PhD thesis, which was presented at ETH on October 26th, 2021. His thesis title was “Understanding the function of the MRE11 complex in homologous recombination” and the study was conducted in the Recombination Mechanisms lab headed by Prof. Petr Cejka at the Institute for Research in Biomedicine, in Bellinzona. His […]