IRB Foundation appoints four new Scientific Council members, including the 2020 Nobel Prize winner for medicine
December 20, 2021 – The Institute for Research in Biomedicine Foundation (IRB Foundation) has appointed four new members to the Scientific Advisory Board of the USI-affiliated Institute. Among these leading academics, Charles M. Rice, Nobel Prize in Medicine in 2020. On 15 December, during the first session of the IRB Foundation held in the new […]
Protein axis to promote genome stability
Bellinzona, March 4, 2022 – The Bloom’s syndrome helicase (BLM) functions in DNA double-strand break repair to prevent crossover recombination. In the absence of BLM, crossover recombination products are increased, leading to a loss of heterozygosity and dramatically increased incidence of cancers. Mechanistically, BLM helicase functions together with a TopoIIIa topoisomerase to process recombination products […]
Divergent and convergent signatures of NK cell memory and clonality
From: Deutsches Rheuma-Forschungszentrum, Berlin (D) PhD Program Coordinator: Silvia Monticelli Date: 10.03.2022 12:00 Speakers: Chiara Romagnani Hybrid Conference ________________________________________________________
CANCOL, a Computer-Assisted Annotation Tool to Facilitate Colocalization and Tracking of Immune Cells
Bellinzona, February 22, 2022 – Four-dimensional imaging data obtained via two-photon intravital microscopy (2P-IVM) are classically analyzed by performing automated cell tracking, a procedure that computes the trajectories followed by each cell. Artificial intelligence (AI) methods are crucial in this analysis process. However, AI can generate detrimental results when applied in biomedical research without considering […]
Niccolò Bianchi awarded PhD
Niccolò Bianchi successfully defended his PhD thesis, which was presented at the University of Bern on December 16th, 2021. His thesis title was “Regulation of inflammatory phenotypes in human T helper lymphocytes” and the study was conducted in the Molecular Immunology lab headed by Dr. Silvia Monticelli at the Institute for Research in Biomedicine, in […]
New paper published in PLoS Biology
Bellinzona, February 15, 2022 – The proliferation and effector function of T lymphocytes of the immune system must be carefully regulated. These cells are indeed crucial sentinels that protect the body from invading pathogens, but their powerful responses must be limited in magnitude and duration to avoid damage to healthy tissues. A network of molecular […]
Giordano Reginato awarded PhD
Giordano Reginato successfully defended his PhD thesis, which was presented at ETH on October 26th, 2021. His thesis title was “Understanding the function of the MRE11 complex in homologous recombination” and the study was conducted in the Recombination Mechanisms lab headed by Prof. Petr Cejka at the Institute for Research in Biomedicine, in Bellinzona. His […]
Covid-19: a new mechanism of immune resistance discovered
Bellinzona, January 31, 2022 – Not only vaccines and antibodies but also innate immunity, the first line of defense that plays a key role in pathogen resistance, plays its part against Sars-CoV-2 and its variants, including Omicron. This is the discovery published in Nature Immunology, the result of an international effort in which researchers from […]
Marcus Thelen nominated for a Life Science Switzerland (LS)2 Honorary membership
Bellinzona, January 28, 2022 – Marcus Thelen has been nominated by the LS2 section Molecular and Cellular Biosciences for a LS2 Honorary membership and selected by an internal committee of different board section members and junior LS2 members for his contributions to LS2 and his outstanding scientific career and achievements. Marcus Thelen has served the […]
Santiago González President of the Association of the Spanish scientists in Switzerland
Bellinzona, January 25, 2022 – Santiago González head of the Infection and Immunity laboratory at the IRB has been elected president of the association of Spanish scientists in Switzerland (ACECH), a non-profit organization created in November 2017 and formed by more than 250 Spanish researchers from all disciplines working in Switzerland. The association aims at […]
