Offerte di lavoro
Prima di applicare ad una offerta di lavoro presso l’IRB, si consiglia di leggere:
Having an outstanding CV is a very good start but is not sufficient to be short listed for an interview, and is definitely not enough per se to get the position your are applying for. Your motivation and career plan are crucial and will be of high impact on the success of your application.
In your motivation letter, which has to be written in English, you need to clearly demonstrate why you want to join the IRB and this group of research in particular. Your application should also contain the e-mail addresses of at least two referees.
If you intend to join the IRB, you should wonder not only what the Institute will bring to you but also what You will bring to the Institute. We ask you not only to be self-critical but also to be scientifically critical with your future team. The Institute is looking for good Scientists not for tasks executors.
Working efficiently is more expected than working hard, even if one does not exclude the other and vice versa.
If finally you have the chance to be short listed for an interview, please prepare it. Look all over our website to know the environment surrounding the research group you are applying to, read their last publications, current projects and research networks; study the core facilities available at the Institute. Even if in the job advertisement you have only a few sentences describing your future project, start to think about it, how you would approach it.
In short, applying at the IRB should not be one of the X applications you are writing and sending. Instead, it should be thoroughly prepared.
Per le applicazioni al Programma di Dottorato non ci sono particolari scadenze: contattare direttamente il Direttore del laboratorio a cui si è interessati mandando il CV e spiegando chiaramente le motivazioni per svolgere un dottorato e il perché della scelta di una linea di ricerca, tutto in inglese.
Servizio civile
La posizione di assistente di ricerca presso uno dei gruppi dell’Istituto di Ricerca in Biomedicina (IRB) permette al civilista di poter assistere attivamente dottorandi e post-dottorati in svariati progetti di ricerca. I compiti svolti dal civilista e il grado di autonomia dipendono soprattutto dal suo titolo di studio e dall’esperienza raccolta sinora. Questi possono riguardare semplici procedure di base standard come mantentimento di culture cellulari, PCR o preparazione di reagenti oppure l’utilizzo di macchinari e tecniche più complesse come citometria di flusso.
Rispetto
L’IRB mira a creare un ambiente vivace, collaborativo e inclusivo, dove le persone si dedicano in modo sicuro e libero alle discussioni scientifiche e alle scoperte. Per raggiungere questo obiettivo, le interazioni tra tutti i membri della comunità dell’IRB dovrebbero essere sempre basate sul rispetto reciproco. L’IRB non tollererà alcun comportamento inappropriato che offenda l’integrità personale, la dignità personale e che ostacoli le pari opportunità. Molestie, bullismo, discriminazioni, atteggiamenti minacciosi e violenza sono tutti comportamenti inaccettabili a tutti i livelli di occupazione e chi commette tali atti ne affronterà le conseguenze, indipendentemente dallo status o dalla posizione. Anche le ritorsioni contro le persone che agiscono in buona fede non saranno tollerate.
Se si dovesse subire un qualsiasi comportamento inappropriato, si prega di segnalarlo. Per ulteriori informazioni, consultate il vostro supervisore o le Risorse Umane. L’IRB è a vostra disposizione e vi sosterrà.
Piano per la parità di genere
L’Istituto di Ricerca in Biomedicina mira a stabilire una cultura del rispetto, a promuovere la diversità e a migliorare le pari opportunità.
Posizioni aperte
There are currently no job vacancies. Please check the website at a later date for any future vacancies.
We are offering a fully funded 3-year PhD position in the Computational
Structural Biology laboratory of Andrea Cavalli at the Institute for Research in
Biomedicine (IRB), Bellinzona.
The PhD project aims to develop and validate novel experimental strategies to
stabilize and reactivate the tumor suppressor PTEN in cancer. The work will
combine biophysical, biochemical, and cellular approaches, complemented by
structural insights, to investigate innovative mechanisms of targeted protein
stabilization with therapeutic relevance.
A central goal of the project is to link molecular mechanisms to functional
outcomes and therapeutic potential through validation in relevant cellular and
preclinical cancer models.
The PhD student will:
• Perform functional validation of lead compounds in cellular systems
and contribute to in vivo testing in relevant cancer models, gaining
insight into efficacy, mechanism of action, and translational potential
• Gain hands-on experience with advanced experimental techniques at
the interface of structural biology, chemical biology, and cancer
research
• Work in close interaction with interdisciplinary collaborators, including
experts in medicinal chemistry and translational oncology
• Be fully integrated into a highly interdisciplinary and international
research environment, with strong links to translational and preclinical
cancer research
Profile:
• MSc. in biology, biochemistry, biophysics, structural biology, or related
fields
• Strong motivation for experimental research
• Interest in cancer biology and drug discoveryWe offer:
• A stimulating international research environment with journal clubs,
seminars given by world-renown scientists, and scientific events
• Outstanding training, mentoring, and regular scientific exchange
• PhD students are enrolled in the PhD program of the Università della
Svizzera italiana, Lugano.
• Access to state-of-the-art infrastructure
• Competitive PhD salary according to Swiss standards
Environment:
Bellinzona is located in the Italian-speaking region of southern Switzerland
and offers a high quality of life, abundant outdoor activities, and excellent
connections to Zurich and Milan.
Starting date: upon agreement
Duration: 3 years
To apply, please send a CV, a short motivation letter, names and email
addresses of two referees to andrea.cavalli@irb.usi.ch
PhD Position on PTEN Stabilization in Cancer (Dr. Andrea Cavalli)
We invite postdoctoral fellows to express their interest in working at the IRB through support by the Swiss National Science Foundation competitive funding-scheme
Ambizione
Applicants from anywhere in the world can apply to obtain a four-years grant to conduct, manage and lead an independent project at a Swiss institution (more info).
General eligibility criteria
IRB Application
Eligible candidates are invited to apply by sending to our Grant Office Team (grantoffice@irb.usi.ch):
The applications will be pre-screened and the candidates with positive evaluation will be contacted by the relevant Group Leader for the next steps.
Deadline for the IRB application: August 3, 2025
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