Thelen Marcus, PhD

Pubblicazioni

• International Union of Basic and Clinical Pharmacology. CXVIII. Update on the Nomenclature for Atypical Chemokine Receptors including ACKR5
  Chevigne, A. Legler, D. F. Rot, A. Sozzani, S. Szpakowska, M. Thelen, M.
  in Pharmacol Rev (2024) Vol. pp
  
• Tumor cells express and maintain HMGB1 in the reduced isoform to enhance CXCR4-mediated migration
  Pirani, E. Paparoditis, P. Pecoraro, M. Danelon, G. Thelen, M. Cecchinato, V. Uguccioni, M.
  in Front Immunol (2024) Vol.15 pp1358800
  
• Transformer-based spatial-temporal detection of apoptotic cell death in live-cell imaging
  Pulfer, A. Pizzagalli, D. U. Gagliardi, P. A. Hinderling, L. Lopez, P. Zayats, R. Carrillo-Barberà, P. Antonello, P. Palomino-Segura, M. Giusti, A. Thelen, M. Gambardella, L. M. Murooka, T. T. Pertz, O. Krause, R. Gonzalez, S.
  in eLife (2023) Vol.12 ppRP90502
  
• GPR182 is a broadly scavenging atypical chemokine receptor influencing Tindependent immunity
  Melgrati, S. Gerken, O. J. Artinger, M. Radice, E. Szpakowska, M. Chevigné, A., D’Uonnolo, G. Antonello, P. Thelen, S. Pelczar, P. Legler, D. Thelen, M.
  in Front. Immunol. (2023) Vol.14 pp1242531.
  
• Reassessing the adrenomedullin scavenging function of ACKR3 in lymphatic endothelial cells
  Sigmund, E. C. Bauer, A. Jakobs, B. D. Tatliadim, H. Tacconi, C. Thelen, M. Legler, D. F. Halin, C.
  in PLoS One (2023) Vol.18 ppe0285597
  
• Atlas of the anatomical localization of atypical chemokine receptors in healthy mice
  Melgrati, S. Radice, E. Ameti, R. Hub, E. Thelen, S. Pelczar, P. Jarrossay, D. Rot, A. Thelen, M.
  in PLoS Biol (2023) Vol.21 ppe3002111
  
• New pairings and deorphanization among the atypical chemokine receptor family – physiological and clinical relevance
  Szpakowska, M. D'Uonnolo, G. Luis, R. Alonso Bartolome, A. Thelen, M. Legler, D. F. Chevigne, A.
  in Front Immunol (2023) Vol.14 pp1133394
  
• Editorial: Insights in cytokines and soluble mediators in immunity: 2022
  Melgrati, S. Sozzani, S. Thelen, M.
  in Front Immunol (2023) Vol.14 pp1194553
  
• Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course
  Muri, J. Cecchinato, V. Cavalli, A. Shanbhag, A. A. Matkovic, M. Biggiogero, M. Maida, P. A. Moritz, J. Toscano, C. Ghovehoud, E. Furlan, R. Barbic, F. Voza, A. De Nadai, G. Cervia, C. Zurbuchen, Y. Taeschler, P. Murray, L. A. Danelon-Sargenti, G. Moro, S. Gong, T. Piffaretti, P. Bianchini, F. Crivelli, V. Podesvova, L. Pedotti, M. Jarrossay, D. Sgrignani, J. Thelen, S. Uhr, M. Bernasconi, E. Rauch, A. Manzo, A. Ciurea, A. Rocchi, M. B. L. Varani, L. Moser, B. Bottazzi, B. Thelen, M. Fallon, B. A. Boyman, O. Mantovani, A. Garzoni, C. Franzetti-Pellanda, A. Uguccioni, M. Robbiani, D. F.
  in Nat Immunol (2023) Vol.24 pp604-611.
  
• Tracking unlabeled cancer cells imaged with low resolution in wide migration chambers via U-NET class-1 probability (pseudofluorescence)
  Antonello, P. Morone, D. Pirani, E. Uguccioni, M. Thelen, M. Krause, R. Pizzagalli, D. U.
  in J Biol Eng (2023) Vol.17 pp5
  
• ACKR3 promotes CXCL12/CXCR4-mediated cell-to-cell-induced lymphoma migration through LTB4 production
  Antonello, P. Pizzagalli, D. U. Foglierini, M. Melgrati, S. Radice, E. Thelen, S. Thelen, M.
  in Front Immunol (2023) Vol.13 pp1067885
  
• CANCOL, a Computer-Assisted Annotation Tool to Facilitate Colocalization and Tracking of Immune Cells in Intravital Microscopy
  Pizzagalli, D. U. Bordini, J. Morone, D. Pulfer, A. Carrillo-Barbera, P. Thelen, B. Ceni, K. Thelen, M. Krause, R. Gonzalez, S. F.
  in J Immunol (2022) Vol. pp
  
• In Vivo Motility Patterns Displayed by Immune Cells Under Inflammatory Conditions
  Pizzagalli, D. U. Pulfer, A. Thelen, M. Krause, R. Gonzalez, S. F.
  in Front Immunol (2022) Vol.12 pp804159
  
• PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation
  Gulluni, F. Prever, L. Li, H. Krafcikova, P. Corrado, I. Lo, W. T. Margaria, J. P. Chen, A. De Santis, M. C. Cnudde, S. J. Fogerty, J. Yuan, A. Massarotti, A. Sarijalo, N. T. Vadas, O. Williams, R. L. Thelen, M. Powell, D. R. Schueler, M. Wiesener, M. S. Balla, T. Baris, H. N. Tiosano, D. McDermott, B. M., Jr. Perkins, B. D. Ghigo, A. Martini, M. Haucke, V. Boura, E. Merlo, G. R. Buchner, D. A. Hirsch, E.
  in Science (2021) Vol.374 ppeabk0410
  
• Ackr3-Venus knock-in mouse lights up brain vasculature
  Ehrlich, A. T. Semache, M. Couvineau, P. Wojcik, S. Kobayashi, H. Thelen, M. Gross, F. Hogue, M. Le Gouill, C. Darcq, E. Bouvier, M. Kieffer, B. L.
  in Mol Brain (2021) Vol.14 pp151
  
• Lymphatic endothelial-cell expressed ACKR3 is dispensable for postnatal lymphangiogenesis and lymphatic drainage function in mice
  Sigmund, E. C. Baur, L. Schineis, P. Arasa, J. Collado-Diaz, V. Vranova, M. Stahl, R. A. K. Thelen, M. Halin, C.
  in PLoS One (2021) Vol.16 ppe0249068
  
• Editorial: Atypical Functions of Leukocyte Chemoattractant Receptors
  Rodríguez-Fernández, JL. Mellado, M. Thelen, M. Murphy, P.M.
  in Front Immunol (2020) Vol.11 pp596902
  
• β-Arrestin1 and β-Arrestin2 Are Required to Support the Activity of the CXCL12/HMGB1 Heterocomplex on CXCR4
  D’Agostino,Gianluca Artinger,Marc Locati,Massimo Perez,Laurent Legler,Daniel F. Bianchi,Marco E. Rüegg,Curzio Thelen,Marcus Marchese,Adriano Rocchi,Marco B. L. Cecchinato,Valentina Uguccioni,Mariagrazia
  in Frontiers in Immunology (2020) Vol.11 pp550824
  
• Marginal Zone Formation Requires ACKR3 Expression on B Cells
  Radice, E. Ameti, R. Melgrati, S. Foglierini, M. Antonello, P. Stahl, R. A. K. Thelen, S. Jarrossay, D. Thelen, M.
  in Cell Report (2020) Vol.32 pp107951
  
• B cell zone reticular cell microenvironments shape CXCL13 gradient formation
  Cosgrove, J. Novkovic, M. Albrecht, S. Pikor, N. B. Zhou, Z. Onder, L. Morbe, U. Cupovic, J. Miller, H. Alden, K. Thuery, A. O'Toole, P. Pinter, R. Jarrett, S. Taylor, E. Venetz, D. Heller, M. Uguccioni, M. Legler, D. F. Lacey, C. J. Coatesworth, A. Polak, W. G. Cupedo, T. Manoury, B. Thelen, M. Stein, J. V. Wolf, M. Leake, M. C. Timmis, J. Ludewig, B. Coles, M. C.
  in Nat Commun (2020) Vol.11 pp3677
  
• CCL20 is a novel ligand for the scavenging atypical chemokine receptor 4
  Matti, C. D'Uonnolo, G. Artinger, M. Melgrati, S. Salnikov, A. Thelen, S. Purvanov, V. Strobel, T. D. Spannagel, L. Thelen, M. Legler, D. F.
  in J Leukoc Biol (2020) Vol.107 pp1137-1154
  
• ACKR4 Recruits GRK3 Prior to beta-Arrestins but Can Scavenge Chemokines in the Absence of beta-Arrestins
  Matti, C. Salnikov, A. Artinger, M. D'Agostino, G. Kindinger, I. Uguccioni, M. Thelen, M. Legler, D. F.
  in Front Immunol (2020) Vol.11 pp720
  
• Protoporphyrin IX tracer fluorescence modulation for improved brain tumor cell lines visualization
  Piffaretti, D. Burgio, F. Thelen, M. Paganetti, P. Reinert, M. D'Angelo, M. L.
  in J Photochem Photobiol B (2019) Vol.201 pp111640
  
• ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens
  Proietti, M. Perruzza, L. Scribano, D. D'Antuono, R. Strati, F. Raffaelli, M. Gonzalez, S. F. Thelen, M. Hardt, W. D. Slack, E. Nicoletti, M. Grassi, F.
  in Nat Commun (2019) Vol.10 pp250
  
• Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis
  Girbl, T. Lenn, T. Perez*, L. Barkaway, A. Thiriot, A. Del Fresno, C. Lynam, E. Hub, E. Thelen, M. Graham, G. Alon, R. Sancho, D. von Andrian, U. H. Voisin, M. B. Rot, A. Nourshargh, S.
  in Immunity (2018) Vol.49 pp1062-1076.
  
• Redox-Mediated Mechanisms Fuel Monocyte Responses to CXCL12/HMGB1 in Active Rheumatoid Arthritis
  Cecchinato, V. D'Agostino, G. Raeli, L. Schiraldi, M. Danelon, G. Manzo, A. Thelen, M. Ciurea, A. Bianchi, M. E. Rubartelli, A. Pitzalis, C. Uguccioni, M.
  in Front Immunol (2018) Vol.9 pp2118
  
• Leukocyte Tracking Database, a collection of immune cell tracks from intravital 2-photon microscopy videos
  Pizzagalli, D. U. Farsakoglu, Y. Palomino-Segura, M. Sintes, J. Marangoni, F. Mempel, T. R. Koh, W. H. Murooka, T. T. Thelen, F. Stein, J. V. Pozzi, G. Thelen, M. Krause, R. Gonzalez, S. F.
  in Sci Data (2018) Vol.5 pp180129
  
• Characterization of a chimeric chemokine as a specific ligand for ACKR3
  Ameti, R. Melgrati, S. Radice, E. Hub, E. Thelen, S. Rot, A. Thelen, M.
  in J Leukoc Biol (2018) Vol.104 pp391-400
  
• Membrane lipid environment: Potential modulation of chemokine receptor function
  Thelen, M. Legler, D. F.
  in Cytokine (2018) Vol.109 pp72-75
  
• New insights in chemokine signaling
  Legler, D. F. Thelen, M.
  in F1000Res (2018) Vol.7 pp95
  
• Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2alpha Scaffolding Function
  Gulluni, F. Martini, M. De Santis, M. C. Ghigo, A. Margaria, J. P. Ciraolo, E. Franco, I. Ala, U. Annaratone, L. Disalvatore, D. Bertalot, G. Viale, G. Noatynska, A. Compagno, M. Sigismund, S. Montemurro, F. Thelen, M. Fan, F. Meraldi, P. Marchio, C. Pece, S. Sapino, A. Chiarle, R. Di Fiore, P. P. Hirsch, E.
  in Cancer Cell (2017) Vol.32 pp444-459 e7
  
• The Atypical Receptor CCRL2 (C-C Chemokine Receptor-Like 2) Does Not Act As a Decoy Receptor in Endothelial Cells
  Mazzotti, C. Gagliostro, V. Bosisio, D. Tiberio, L. Thelen, M. Sozzani, S.
  in Front Immunol (2017) Vol.8 pp1233
  
• ACKR3 expression on diffuse large B cell lymphoma is required for tumor spreading and tissue infiltration
  Puddinu, V. Casella, S. Radice, E. Dirnhofer, S. Bertoni, F. Thelen, M.
  in Oncotarget (2017) Vol.8 pp85068-85084
  
• CXCL12alpha/SDF-1 from perisynaptic Schwann cells promotes regeneration of injured motor axon terminals
  Negro, S. Lessi, F. Duregotti, E. La Ferla, M. Franceschi, S. Menicagli, M. Bergamin, E. Radice, E. Thelen, M. Megighian, A. Pirazzini, M. Mazzanti, C. M. Rigoni, M. Montecucco, C.
  in EMBO Mol Med (2017) Vol.9 pp1000-1010
  
• Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4
  Collins, P. J. McCully, M. L. Martinez-Munoz, L. Wheeldon, J. Caucheteux, S. Thelen, S. Cecchinato, V. Laufer, J. M. Purvanov, V. Monneau, Y. R. Lortat-Jacob, H. Legler, D. F. Uguccioni, M. Thelen, M. Piguet, V. Mellado, M. Moser, B.
  in FASEB J (2017) Vol.31 pp3084-3097
  
• Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation
  Ziarek, J. J. Kleist, A. B. London, N. Montpas, N. Bonneterre, J. St-Onge, G. DiCosmo-Ponticello, C. J. Koplinski, C. A. Roy, I. Stephens, B. Thelen, S. Veldkamp, C. T. Coffman, F. D. Cohen, M. C. Dwinell, M. B. Thelen, M. Peterson, F. C. Heveker, N. Volkman, B. F.
  in Sci Signal (2017) Vol.10 ppeaah5756
  
• Modulation of chemokine receptor function by cholesterol: new prospects for pharmacological intervention
  Legler, D. F. Matti, C. Laufer, J. M. Purvanov, V. Uetz-von Allmen, E. Thelen, M.
  in Mol Pharmacol (2017) Vol.91 pp331-338
  
• Chemokines: Chemistry, Biochemistry and Biological Function
  Legler, D. F. Thelen, M.
  in Chimia (2016) Vol.70 pp856-859
  
• Altered CXCL12 expression reveals a dual role of CXCR4 in osteosarcoma primary tumor growth and metastasis
  Neklyudova, O. Arlt, M. J. Brennecke, P. Gvozdenovic, A. Kuzmanov, A. Robl, B. Botter, S. M. Born, W. Fuchs, B.
  in J Cancer Res Clin Oncol (2016) Vol.142 pp1739-1750
  
• Role of CXCR4-mediated bone marrow colonization in CNS infiltration by T cell acute lymphoblastic leukemia
  Jost, T. R. Borga, C. Radaelli, E. Perruzza, L. Omodho, L. Cazzaniga, G. Biondi, A. Indraccolo, S. Thelen, M. Te Kronnie, G. Grassi, F.
  in J Leukoc Biol (2016) Vol.99 pp1077-87
  
• Monitoring Scavenging Activity of Chemokine Receptors
  Moepps, B. Thelen, M.
  in Methods Enzymol (2015) Vol.570 pp87-118
  
• Biased signaling pathways via CXCR3 control the development and function of CD4+ T cell subsets
  Karin, N. Wildbaum, G. Thelen, M.
  in J Leukoc Biol (2015) Vol.99 pp857-62
  
• Association of eukaryotic translation initiation factor eIF2B with fully solubilized CXCR4
  Palmesino, E. Apuzzo, T. Thelen, S. Langen, H. Thelen, M.
  in J Leukoc Biol (2015) Vol.99 pp971-8
  
• An atypical addition to the chemokine receptor nomenclature: IUPHAR Review 15
  Bachelerie, F. Graham, G. J. Locati, M. Murphy, P. M. Nibbs, R. Rot, A. Sozzani, S. Thelen, M.
  in Br J Pharmacol (2015) Vol.172 pp3945-9
  
• Herpes simplex virus enhances chemokine function through modulation of receptor trafficking and oligomerization
  Martinez-Martin, N. Viejo-Borbolla, A. Martin, R. Benovic, J. L. Thelen, M. Alcami, A.
  in Nat Commun (2015) Vol.6 pp6163
  
• ATP-Gated Ionotropic P2X7 Receptor Controls Follicular T Helper Cell Numbers in Peyer’s Patches to Promote Host-Microbiota Mutualism
  Proietti, M. Cornacchione, V. Rezzonico Jost, T. Faliti, C. E. Perruzza, L. Rigoni, R. Radaelli, E. Caprioli, F. Preziuso, S. Brannetti, B. Thelen, M. McCoy, K. D. Slack, E. Traggiai, E. Grassi, F.
  in Immunity (2014) Vol.41 pp789-801
  
• CXCR7 prevents excessive CXCL12-mediated downregulation of CXCR4 in migrating cortical interneurons
  Abe, P. Mueller, W. Schutz, D. Thelen, M. Zhang, P. Stumm, R.
  in Development (2014) Vol.141 pp1857-63
  
• CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis
  Zohar, Y. Wildbaum, G. Novak, R. Thelen, M. Alon, R. Barsheshet, Y. Karp, C. L. Karin, N.
  in J Clin Invest (2014) Vol.124 pp2009-22
  
• New nomenclature for atypical chemokine receptors
  Bachelerie, F. Graham, G. J. Locati, M. Murphy, P. M. Nibbs, R. Rot, A. Sozzani, S. Thelen, M.
  in Nat Immunol (2014) Vol.15 pp207-8
  
• CXCR4 antibody treatment suppresses metastatic spread to the lung of intratibial human osteosarcoma xenografts in mice
  Brennecke, P. Arlt, M. J. Campanile, C. Gvozdenovic, A. Apuzzo, T. Thelen, M. Born, W. Fuchs, B.
  in Clin Exp Metastasis (2014) Vol.31 pp339-49
  
• CXCR7 influences the migration of B cells during maturation
  Humpert, M. L. Pinto, D. Jarrossay, D.
  in Eur J Immunol (2013) Vol.44 pp694-705
  
• International Union of Pharmacology. LXXXIX. Update on the Extended Family of Chemokine Receptors and Introducing a New Nomenclature for Atypical Chemokine Receptors
  Bachelerie, F. Ben-Baruch, A. Burkhardt, A. M. Farber, J. M. Graham, G. J. Horuk, R. Sparre-Ulrich, A. H. Locati, M. Luster, A. D. Mantovani, A. Matsushima, K. Murphy, P. M. Nibbs, R. Nomiyama, H. Power, C. A. Proudfoot, A. E. Rosenkilde, M. M. Rot, A. Sozzani, S. Thelen, M. Yoshie, O. Zlotnik, A.
  in Pharmacol Rev (2013) Vol.66 pp1-79
  Erratum in: Pharmacol Rev. 2014 Apr;66(2):467
• Expression of the Chemokine Receptor CXCR7 in CXCR4-Expressing Human 143B Osteosarcoma Cells Enhances Lung Metastasis of Intratibial Xenografts in SCID Mice
  Brennecke, P. Arlt, M. J. Muff, R. Gvozdenovic, A. Husmann, K. Holzwarth, N. Cameroni, E. Ehrensperger, F. Thelen, M. Born, W. Fuchs, B.
  in PLoS One (2013) Vol.8 ppe74045
  
• Immune response: steroids drive dendritic cells
  Jarrossay, D. Thelen, M.
  in Nat Immunol (2013) Vol.14 pp424-426
  
• Expression of CXCL12 receptors in B cells from Mexican Mestizos patients with systemic lupus erythematosus
  Biajoux, V. Bignon, A. Freitas, C. Thelen, M. Lima, G. Jakez-Ocampo, J. Emilie, D. Llorente, L. Balabanian, K.
  in J Transl Med (2012) Vol.10 pp251
  
• The biochemistry and biology of the atypical chemokine receptors
  Graham, G. J. Locati, M. Mantovani, A. Thelen, M.
  in Immunol Lett (2012) Vol.145 pp30-8
  
• Complementary methods provide evidence for the expression of CXCR7 on human B cells
  Humpert, M. L. Tzouros, M. Thelen, S. Levoye, A. Arenzana-Seisdedos, F. Balabanian, K. Bachelerie, F. Langen, H. Thelen, M.
  in Proteomics (2012) Vol.12 pp1938-48
  
• CCR2 Acts as Scavenger for CCL2 during Monocyte Chemotaxis
  Volpe, S. Cameroni, E. Moepps, B. Apuzzo, T. Thelen, M.
  in PLoS One (2012) Vol.7 ppe37208
  
• Enhancement of chemokine function as an immunomodulatory strategy employed by human herpesviruses
  Viejo-Borbolla, A. Martinez-Martin, N. Nel, H. J. Martin, R. Blanco, S. Arenzana-Seisdedos, F. Thelen, M. Fallon, P. G. Alcami, A.
  in PLoS Pathog (2012) Vol.8 ppe1002497
  
• The guanine-nucleotide-exchange factor P-Rex1 is activated by protein phosphatase 1alpha
  Barber, M. A. Hendrickx, A. Beullens, M. Oxley, D. Thelen, S. Thelen, M. Bollen, M. Welch, H. C.
  in Biochem J (2012) Vol.443 pp173-83
  
• Polarization of migrating monocytic cells is independent of PI 3-kinase activity
  Volpe, S. Thelen, S. Pertel, T. Thelen, M.
  in PLoS One (2010) Vol.5 ppe10159
  
• CXCR7 functions as a scavenger for CXCL12 and CXCL11
  Naumann, U. Cameroni, E. Pruenster, M. Raz, E. Zerwes, H. G. Rot, A. Thelen, M.
  in PLoS One (2010) Vol.5 ppe9175
  
• Chemokine receptor oligomerization: functional considerations
  Thelen, M. Munoz, L. M. Rodriguez-Frade, J. M.
  in Curr Opin Pharmacol (2009) Vol.10 pp38-43
  
• How chemokines invite leukocytes to dance
  Thelen, M. Stein, J. V.
  in Nat Immunol (2008) Vol.9 pp953-9
  
• A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells
  Hartmann, T. N. Grabovsky, V. Pasvolsky, R. Buss, E. C. Spiegel, A. Nagler, A. Lapidot, T. Thelen, M. Alon, R.
  in J Leukoc Biol (2008) Vol.84 pp1130-40
  
• CXCR7, CXCR4 and CXCL12: an eccentric trio?
  Thelen, M. Thelen, S.
  in J Neuroimmunol (2008) Vol.198 pp9-13
  
• Membrane translocation of P-Rex1 is mediated by G protein betagamma subunits and phosphoinositide 3-kinase
  Barber, M. A. Donald, S. Thelen, S. Thelen, M. Welch, H. C.
  in J Biol Chem (2007) Vol.282 pp29967-76
  
• Bcl10 controls TCR- and FcgammaR-induced actin polymerization
  Rueda, D. Gaide, O. Ho, L. Niedergang, F. Hailfinger, S. Rebeaud, F. Guzzardi, M. Conne, B. Thelen, M. Delon, J. Ferch, U. Mak, T. W. Ruland, J. Schwaller, J. Thome, M.
  in J Immunol (2007) Vol.178 pp4373-84
  
• Differences in CXCR4-mediated signaling in B cells
  Palmesino, E. Moepps, B. Gierschik, P.
  in Immunobiology (2006) Vol.211 pp377-89
  
• Expression and regulation of the orphan receptor RDC1 and its putative ligand in human dendritic and B cells
  Infantino, S. Moepps, B. Thelen, M.
  in J Immunol (2006) Vol.176 pp2197-207
  
• P-Rex1 regulates neutrophil function
  Welch, H. C. Condliffe, A. M. Milne, L. J. Hill, K. Webb, L. M. Okkenhaug, K. Coadwell, W. J. Andrews, S. R. Thelen, M. Jones, G. E. Hawkins, P. T. Stephens, L. R.
  in Curr Biol (2005) Vol.15 pp1867-73
  
• The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes
  Balabanian, K. Lagane, B. Infantino, S. Harriague, J. Moepps, B. Arenzana-Seisdedos, F. Thelen, M. Bachelerie, F.
  in J Biol Chem (2005) Vol.280 pp35760-6
  
• Unusual chemokine receptor antagonism involving a mitogen-activated protein kinase pathway
  Ogilvie, P. Thelen, S. Moepps, B. da Silva Campos, A. C. Baggiolini, M. Thelen, M.
  in J Immunol (2004) Vol.172 pp6715-22
  
• Mitotic and stress-induced phosphorylation of HsPI3K-C2alpha targets the protein for degradation
  Didichenko, S. A. Fragoso, C. M. Thelen, M.
  in J Biol Chem (2003) Vol.278 pp26055-64
  
• Phosphatidylinositol 3-kinase c2alpha contains a nuclear localization sequence and associates with nuclear speckles
  Didichenko, S. A. Thelen, M.
  in J Biol Chem (2001) Vol.276 pp48135-42
  
• Is dimerization of chemokine receptors functionally relevant?
  Thelen, M. Baggiolini, M.
  in Sci STKE (2001) Vol.2001 ppPE34
  
• Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane
  Maira, S. M. Galetic, I. Brazil, D. P. Ingley, E. Thelen, M. Hemmings, B. A.
  in Science (2001) Vol.294 pp374-80
  
• Dancing to the tune of chemokines
  Thelen, M.
  in Nat Immunol (2001) Vol.2 pp129-34
  
• Rapid inactivation of stromal cell-derived factor-1 by cathepsin G associated with lymphocytes
  Delgado, M. B. Clark-Lewis, I. Loetscher, P. Thelen, M. Baggiolini, M. Wolf, M.
  in Eur J Immunol (2001) Vol.31 pp699-707
  
• Rac and phosphatidylinositol 3-kinase regulate the protein kinase B in Fc epsilon RI signaling in RBL 2H3 mast cells
  Djouder, N. Schmidt, G. Frings, M. Thelen, M. Aktories, K.
  in J Immunol (2001) Vol.166 pp1627-34
  
• Evidence for a pool of coronin in mammalian cells that is sensitive to PI 3-kinase
  Didichenko, S. A. Segal, A. W. Thelen, M.
  in FEBS Lett (2000) Vol.485 pp147-52
  
• Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes
  Tilton, B. Ho, L. Oberlin, E. Baleux, F. Clark-Lewis, I. Thelen, M.
  in J Exp Med (2000) Vol.192 pp313-24
  
• GAP43, MARCKS, and CAP23 modulate PI(4,5)P(2) at plasmalemmal rafts, and regulate cell cortex actin dynamics through a common mechanism
  Laux, T. Fukami, K. Thelen, M. Frey, D. Caroni, P.
  in J Cell Biol (2000) Vol.149 pp1455-72
  
• Stromal cell-derived factor-1alpha associates with heparan sulfates through the first beta-strand of the chemokine
  Amara, A. Lorthioir, O. Valenzuela, A. Thelen, M. Montes, M. Virelizier, J. L. Delepierre, M. Baleux, F. Lortat-Jacob, H. Arenzana-Seisdedos, F.
  in J Biol Chem (1999) Vol.274 pp23916-25
  
• Two constituents of the initiation complex of the mannan-binding lectin activation pathway of complement are encoded by a single structural gene
  Stover, C. M. Thiel, S. Thelen, M. Vorup-Jensen, T. Jensenius, J. C. Schwaeble, W. J.
  in J Immunol (1999) Vol.162 pp3481-90
  
• Inactivation and dephosphorylation of protein kinase Balpha (PKBalpha) promoted by hyperosmotic stress
  Meier, R. Thelen, M. Hemmings, B. A.
  in EMBO J (1998) Vol.17 pp7294-303
  
• G-protein coupled receptor-mediated activation of PI 3-kinase in neutrophils
  Thelen, M. Didichenko, S. A.
  in Ann N Y Acad Sci (1998) Vol.832 pp368-82
  
• Caspase-mediated proteolysis during apoptosis: insights from apoptotic neutrophils
  Sanghavi, D. M. Thelen, M. Thornberry, N. A. Rosen, A.
  in FEBS Lett (1998) Vol.422 pp179-84
  
• G-Protein-coupled receptors and Fcgamma-receptors mediate activation of Akt/protein kinase B in human phagocytes
  Tilton, B. Andjelkovic, M. Didichenko, S. A. Thelen, M.
  in J Biol Chem (1997) Vol.272 pp28096-101
  
• Influence of tyrosine phosphorylation on protein interaction with FcgammaRIIa
  Ibarrola, I. Vossebeld, P. J. Homburg, C. H. Roos, D. Verhoeven, A. J.
  in Biochim Biophys Acta (1997) Vol.1357 pp348-58
  
• Eotaxin-2, a novel CC chemokine that is selective for the chemokine receptor CCR3, and acts like eotaxin on human eosinophil and basophil leukocytes
  Forssmann, U. Uguccioni, M. Loetscher, P. Langen, H. Thelen, M. Baggiolini, M.
  in J Exp Med (1997) Vol.185 pp2171-6
  
• Properdin, a positive regulator of complement activation, is released from secondary granules of stimulated peripheral blood neutrophils
  Wirthmueller, U. Dewald, B. Thelen, M. Stover, C. Whaley, K. North, J. Eggleton, P. Reid, K. B. Schwaeble, W. J.
  in J Immunol (1997) Vol.158 pp4444-51
  
• The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101
  Stephens, L. R. Eguinoa, A. Erdjument-Bromage, H. Cooke, F. Coadwell, J. Smrcka, A. S. Thelen, M. Cadwallader, K. Tempst, P. Hawkins, P. T.
  in Cell (1997) Vol.89 pp105-14
  
• Regulation of the urokinase-type plasminogen activator gene by the oncogene Tpr-Met involves GRB2
  Besser, D. Bardelli, A. Didichenko, S. Comoglio, P. M. Ponzetto, C. Nagamine, Y.
  in Oncogene (1997) Vol.14 pp705-11
  
• Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase
  Didichenko, S. A. Tilton, B. Hemmings, B. A. Thelen, M.
  in Curr Biol (1996) Vol.6 pp1271-8
  
• Monocyte chemotactic protein 4 (MCP-4), a novel structural and functional analogue of MCP-3 and eotaxin
  Uguccioni, M. Loetscher, P. Forssmann, U. Li, H. Lima, S. H. Li, Y. Kreider, B. Garotta, G. Thelen, M. Baggiolini, M.
  in J Exp Med (1996) Vol.183 pp2379-84
  
• PI 3-kinase-dependent and independent chemotaxis of human neutrophil leukocytes
  Thelen, M. Uguccioni, M. Bosiger, J.
  in Biochem Biophys Res Commun (1995) Vol.217 pp1255-62
  
• A comparison of post-receptor signal transduction events in Jurkat cells transfected with either IL-8R1 or IL-8R2. Chemokine mediated activation of p42/p44 MAP-kinase (ERK-2)
  Jones, S. A. Moser, B. Thelen, M.
  in FEBS Lett (1995) Vol.364 pp211-4
  
• Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes
  Thelen, M. Wymann, M. P. Langen, H.
  in Proc Natl Acad Sci U S A (1994) Vol.91 pp4960-4
  
• Phospholipases and protein kinases during phagocyte activation
  Thelen, M. Wirthmueller, U.
  in Curr Opin Immunol (1994) Vol.6 pp106-12
  
• Neutrophil signal transduction and activation of the respiratory burst
  Thelen, M. Dewald, B. Baggiolini, M.
  in Physiol Rev (1993) Vol.73 pp797-821
  
• MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin
  Hartwig, J. H. Thelen, M. Rosen, A. Nairn, A. C. Aderem, A.
  in Nature (1992) Vol.356 pp618-22
  
• The phagocytes and the respiratory burst
  Baggiolini, M. Thelen, M.
  in Oxidative Stress II (1991) Vol. pp
  
• Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane
  Thelen, M. Rosen, A. Nairn, A. C.
  in Nature (1991) Vol.351 pp320-2
  
• GM-1, a clone of the monoblastic phagocyte U937 that expresses a large respiratory burst capacity upon activation with interferon-gamma
  Garotta, G. Thelen, M. Delia, D. Baggiolini, M.
  in J Leukoc Biol (1991) Vol.49 pp294-301
  
• Activation of protein kinase C results in the displacement of its myristoylated, alanine-rich substrate from punctate structures in macrophage filopodia
  Rosen, A. Keenan, K. F. Thelen, M. Aderem, A.
  in J Exp Med (1990) Vol.172 pp1211-5
  
• Tumor necrosis factor alpha modifies agonist-dependent responses in human neutrophils by inducing the synthesis and myristoylation of a specific protein kinase C substrate
  Thelen, M. Rosen, A. Nairn, A. C.
  in Proc Natl Acad Sci U S A (1990) Vol.87 pp5603-7
  
• Reconstitution of cell-free NADPH-oxidase from human monocytes and comparison with neutrophils
  Thelen, M. Baggiolini, M.
  in Blood (1990) Vol.75 pp2223-8
  
• Staurosporine inhibits the respiratory burst and induces exocytosis in human neutrophils
  Dewald, B. Thelen, M. Wymann, M. P.
  in Biochem J (1989) Vol.264 pp879-84
  
• Structure and properties of a novel neutrophil-activating factor (NAF) produced by human monocytes
  Walz, A. Peveri, P. Aschauer, H. Kernen, P. Dewald, B. Baggiolini, M.
  in Agents Actions (1989) Vol.26 pp148-50
  
• [Properties and activation mechanism of neutrophilic leukocytes]
  Baggiolini, M. Deranleau, D. A. Dewald, B. von Tscharner, V. Wymann, M. P.
  in Arzneimittelforschung (1989) Vol.39 pp177-80
  
• Synthesis and expression in Escherichia coli of the gene encoding monocyte-derived neutrophil-activating factor: biological equivalence between natural and recombinant neutrophil-activating factor
  Lindley, I. Aschauer, H. Seifert, J. M. Brunowsky, W. Kownatzki, E. Thelen, M. Peveri, P. Dewald, B. von Tscharner, V. et al.,
  in Proc Natl Acad Sci U S A (1988) Vol.85 pp9199-203
  
• Two transduction sequences are necessary for neutrophil activation by receptor agonists
  Dewald, B. Thelen, M. Baggiolini, M.
  in J Biol Chem (1988) Vol.263 pp16179-84
  
• Mechanism of neutrophil activation by NAF, a novel monocyte-derived peptide agonist
  Thelen, M. Peveri, P. Kernen, P. Walz, A. Baggiolini, M.
  in FASEB J (1988) Vol.2 pp2702-6
  
• The neutrophil leukocyte. Properties and mechanism of activation
  Baggiolini, M. Deranleau, D. A. Dewald, B. von Tscharner. V. et al.
  in Dynamics of Membrane Proteins and Cellular Energetics (1988) Vol. pp
  
• Activation of monocytes by interferon-gamma has no effect on the level or affinity of the nicotinamide adenine dinucleotide-phosphate oxidase and on agonist-dependent superoxide formation
  Thelen, M. Wolf, M. Baggiolini, M.
  in J Clin Invest (1988) Vol.81 pp1889-95
  
• Effects of PAF on neutrophils and mononuclear phagocytes
  Baggiolini, M. Dewald, B. Thelen, M.
  in Prog Biochem Pharmacol (1988) Vol.22 pp90-105
  
• Functional reconstitution of proton-pumping cytochrome-c oxidase in phospholipid vesicles
  Muller, M. Thelen, M. O'Shea, P.
  in Methods Enzymol (1986) Vol.126 pp78-87
  
• Criteria for the measurement of proton translocation by reconstituted membrane proteins: cytochrome c oxidase
  O'Shea, P. Thelen, M. Azzi, A.
  in Biochem. Soc. Trans. (1985) Vol. pp685-686
  
• Studies on the molecular basis of H+ transfer through phospholipid membranes
  O'Shea, P. Thelen, M. Azzi, A.
  in Biochem. Soc. Trans. (1985) Vol. pp682-683
  
• New insights on the cytochrome c oxidase proton pump
  Thelen, M. O'Shea, P. S. Azzi, A.
  in Biochem J (1985) Vol.227 pp163-7
  
• Proton translocation by a native and subunit III-depleted cytochrome c oxidase reconstituted into phospholipid vesicles. Use of fluorescein-phosphatidylethanolamine as an intravesicular pH indicator
  Thelen, M. O'Shea, P. S. Petrone, G.
  in J Biol Chem (1985) Vol.260 pp3626-31
  
• Molecular properties of reconstituted cytochrome c oxidase: new evidence supports vectorial proton translocation
  Azzi, A. Muller, M. O'Shea, P.
  in J Inorg Biochem (1985) Vol.23 pp341-7
  
• On the logic of the application of double-inhibitor titrations for the elucidation of the mechanisms of energy coupling
  O'Shea, P. S. Thelen, M.
  in FEBS Lett (1984) Vol.176 pp79-82
  
• The use of fluorescein-dipalmitoylphosphatidylethanolamine for measuring pH-changes in the internal compartment of phospholipid vesicles
  Thelen, M. Petrone, G. O'Shea, P. S.
  in Biochim Biophys Acta (1984) Vol.766 pp161-8
  
• Intra-vesicular pH-changes in cytochrome c oxidase vesicles as a result of ferrocytochrome c oxidation
  Thelen, M. O'Shea, P. Petrone, G.
  in (1984) Vol. pp169-170
  
• Drug-induced lipid peroxidation in mice–V. Ethane production and glutathione release in the isolated liver upon perfusion with acetaminophen
  Thelen, M. Wendel, A.
  in Biochem Pharmacol (1983) Vol.32 pp1701-6
  
• Studies on the molecular basis of H+ translocation by cytochrome c oxidase
  Casey, R. P. Broger, C. Thelen, M.
  in J Bioenerg Biomembr (1981) Vol.13 pp219-28
  
• The proton pump of cytochrome c oxidase: Inhibition by carbodiimides
  Azzi, A. Casey, R. P. Thelen, M.
  in (1980) Vol. pp21-22
  
• Dicyclohexylcarbodiimide binds specifically and covalently to cytochrome c oxidase while inhibiting its H+-translocating activity
  Casey, R. P. Thelen, M. Azzi, A.
  in J Biol Chem (1980) Vol.255 pp3994-4000
  
• Hydrophobic interactions, proton movements and dicyclohexylcarbodiimide labeling of cytochrome c oxidase
  Azzi, A. Bisson, R. Casey, R. P. Montecucco, C. Thelen, M. et al.
  in Membrane Bioenergetics (1979) Vol. pp
  
• The application of fluorescence spectroscopy to the study of biological membranes
  Casey, R. P. Thelen, M. Azzi, A.
  in Membrane proteins (1979) Vol. pp
  
• The modes of inhibition of proton translocation by cytochrome c oxidase
  Casey, R. P. Thelen, M. Azzi, A.
  in Metalloproteins: Structure, Model Function and Clinical Chemistry (1979) Vol. pp
  
• Dicyclohexylcarbodiimide inhibits proton translocation by cytochrome c oxidase
  Casey, R. P. Thelen, M. Azzi, A.
  in Biochem Biophys Res Commun (1979) Vol.87 pp1044-51