Cavalli Andrea, PhD

Publications

• Ultrapotent IgA dimeric antibodies neutralize emerging Omicron variants
  Zuo, F. Cao, Y. Sun, R. Wang, Q. Simonelli, L. Du, L. Bertoglio, F. Schubert, M. Guerra, C. Cavalli, A. Hust, M. Robbiani, D. F. Varani, L. Abolhassani, H. Xie, X. S. Hammarstrom, L. Marcotte, H. Pan-Hammarstrom, Q.
  in J Virol (2024) Vol. ppe0174024
  
• A first-in-class Wiskott-Aldrich syndrome protein activator with antitumor activity in hematologic cancers
  Spriano, F. Sartori, G. Sgrignani, J. Barnabei, L. Arribas, A. J. Guala, M. Del Amor, A. M. C. Tomasso, M. R. Tarantelli, C. Cascione, L. Golino, G. Riveiro, M. E. Bortolozzi, R. Lupia, A. Paduano, F. Huguet, S. Rezai, K. Rinaldi, A. Margheriti, F. Ventura, P. Guarda, G. Costa, G. Rocca, R. Furlan, A. Verdonk, L. M. Innocenti, P. Martin, N. I. Viola, G. Driessen, C. Zucca, E. Stathis, A. Gahtory, D. Van den Nieuwboer, M. Bornhauser, B. Alcaro, S. Trapasso, F. Cristobal, S. Padrick, S. B. Pazzi, N. Cavalli, F. Cavalli, A. Gaudio, E. Bertoni, F.
  in Haematologica (2024) Vol.109 pp3602-3614
  
• PI3Kdelta activation, IL6 overexpression, and CD37 loss cause resistance to naratuximab emtansine in lymphomas
  Arribas, A. J. Napoli, S. Gaudio, E. Herbaux, C. Cannas, E. Tarantelli, C. Bordone Pittau, R. Cascione, L. Munz, N. Aresu, L. Sgrignani, J. Rinaldi, A. Kwee, I. Rossi, D. Cavalli, A. Zucca, E. Stussi, G. Stathis, A. Sloss, C. Davids, M. S. Bertoni, F.
  in Blood Adv (2024) Vol.8 pp6268-6281
  
• Exploration of isatin-based inhibitors of SARS-CoV-2 Nsp15 endoribonuclease
  Rampias, T. Antoniou, T. Stevaert, A. Kravariti, L. Van Loy, B. Vandeput, J. Sgrignani, J. Filippidou, N. Locatelli, P. Samiotaki, M. Tzakos, E. P. Cavalli, A. Naesens, L. Sideris, D. C. Tzakos, A. G.
  in Eur J Med Chem (2024) Vol.279 pp116886
  
• Targeting senescence induced by age or chemotherapy with a polyphenol-rich natural extract improves longevity and healthspan in mice
  Zumerle, S. Sarill, M. Saponaro, M. Colucci, M. Contu, L. Lazzarini, E. Sartori, R. Pezzini, C. Rinaldi, A. Scanu, A. Sgrignani, J. Locatelli, P. Sabbadin, M. Valdata, A. Brina, D. Giacomini, I. Rizzo, B. Pierantoni, A. Sharifi, S. Bressan, S. Altomare, C. Goshovska, Y. Giraudo, C. Luisetto, R. Iaccarino, L. Torcasio, C. Mosole, S. Pasquini, E. Pellegrini, L. Peron, G. Fassan, M. Masiero, S. Giori, A. M. Dall'Acqua, S. Auwerx, J. Cippa, P. Cavalli, A. Bolis, M. Sandri, M. Barile, L. Montopoli, M. Alimonti, A.
  in Nat Aging (2024) Vol.4 pp1231-1248
  
• A first-in-class Wiskott-Aldrich syndrome protein activator with anti-tumor activity in hematologic cancers
  Spriano, F. Sartori, G. Sgrignani, J. Barnabei, L. Arribas, A. J. Guala, M. Del Amor, A. M. C. Tomasso, M. R. Tarantelli, C. Cascione, L. Golino, G. Riveiro, M. E. Bortolozzi, R. Lupia, A. Paduano, F. Huguet, S. Rezai, K. Rinaldi, A. Margheriti, F. Ventura, P. Guarda, G. Costa, G. Rocca, R. Furlan, A. Verdonk, L. M. Innocenti, P. Martin, N. I. Viola, G. Driessen, C. Zucca, E. Stathis, A. Gahtory, D. Van den Nieuwboer, M. Bornhauser, B. Alcaro, S. Trapasso, F. Cristobal, S. Padrick, S. B. Pazzi, N. Cavalli, F. Cavalli, A. Gaudio, E. Bertoni, F.
  in Haematologica (2024) Vol. pp
  
• Computational Design of Novel Cyclic Peptides Endowed with Autophagy-Inhibiting Activity on Cancer Cell Lines
  Albani, M. Fassi, E. M. A. Moretti, R. M. Garofalo, M. Montagnani Marelli, M. Roda, G. Sgrignani, J. Cavalli, A. Grazioso, G.
  in Int J Mol Sci (2024) Vol.25 pp4622
  
• A critical view on autoantibodies in lupus nephritis: Concrete knowledge based on evidence
  Bruschi, M. Angeletti, A. Prunotto, M. Meroni, P. L. Ghiggeri, G. M. Zeus, consortium Moroni, G. Sinico, R. A. Franceschini, F. Fredi, M. Vaglio, A. Cavalli, A. Scapozza, L. Patel, J. J. Tan, J. C. Lo, K. C. Cavagna, L. Petretto, A. Pratesi, F. Migliorini, P. Locatelli, F. Pazzola, G. Pesce, G. Giannese, D. Manfredi, A. Ramirez, G. A. Esposito, P. Murdaca, G. Negrini, S. Bui, F. Trezzi, B. Emmi, G. Cavazzana, I. Binda, V. Fenaroli, P. Pisan, I. Montecucco, C. Santoro, D. Scolari, F. Mescia, F. Volpi, S. Mosca, M. Tincani, A. Ravelli, A. Murtas, C. Candiano, G. Caridi, G. La Porta, E. Verrina, E.
  in Autoimmun Rev (2024) Vol.23 pp103535
  
• Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents infection of Omicron lineages
  Marcotte, H. Cao, Y. Zuo, F. Simonelli, L. Sammartino, J. C. Pedotti, M. Sun, R. Cassaniti, I. Hagbom, M. Piralla, A. Yang, J. Du, L. Percivalle, E. Bertoglio, F. Schubert, M. Abolhassani, H. Sherina, N. Guerra, C. Borte, S. Rezaei, N. Kumagai-Braesch, M. Xue, Y. Su, C. Yan, Q. He, P. Gronwall, C. Klareskog, L. Calzolai, L. Cavalli, A. Wang, Q. Robbiani, D. F. Hust, M. Shi, Z. Feng, L. Svensson, L. Chen, L. Bao, L. Baldanti, F. Xiao, J. Qin, C. Hammarstrom, L. Yang, X. Varani, L. Xie, X. S. Pan-Hammarstrom, Q.
  in Proc Natl Acad Sci U S A (2024) Vol.121 ppe2315354120
  
• Neutralisation activity of mucosal IgA against XBB sublineages and BA.2.86
  Zuo, F. Cao, Y. Sun, R. Yisimayi, A. Du, L. Bertoglio, F. Schubert, M. Guerra, C. Cavalli, A. Hust, M. Robbiani, D. F. Abolhassani, H. Xie, X. S. Hammarstrom, L. Marcotte, H. Pan-Hammarstrom, Q.
  in Lancet Infect Dis (2023) Vol.24 ppe7-e9
  
• A combination of two resistance mechanisms is critical for tick-borne encephalitis virus escape from a broadly neutralizing human antibody
  Svoboda, P. Haviernik, J. Bednar, P. Matkovic, M. Cervantes Rincon, T. Keeffe, J. Palus, M. Salat, J. Agudelo, M. Nussenzweig, M. C. Cavalli, A. Robbiani, D. F. Ruzek, D.
  in Cell Rep (2023) Vol.42 pp113149
  
• ETS1 phosphorylation at threonine 38 is associated with the cell of origin of diffuse large B cell lymphoma and sustains the growth of tumour cells
  Chung, E. Y. L. Sartori, G. Ponzoni, M. Cascione, L. Priebe, V. Xu-Monette, Z. Y. Fang, X. Zhang, M. Visco, C. Tzankov, A. Rinaldi, A. Sgrignani, J. Zucca, E. Rossi, D. Cavalli, A. Inghirami, G. Scott, D. W. Young, K. H. Bertoni, F.
  in Br J Haematol (2023) Vol. pp
  
• Tau protein binds to the P53 E3 ubiquitin ligase MDM2
  Sola, M. Rendon-Angel, A. Rojo Martinez, V. Sgrignani, J. Magrin, C. Piovesana, E. Cavalli, A. Paganetti, P. Papin, S.
  in Sci Rep (2023) Vol.13 pp10208
  
• Mechanistic Insights into the Antibiofilm Mode of Action of Ellagic Acid
  Ratti, A. Fassi, E. M. A. Forlani, F. Mori, M. Villa, F. Cappitelli, F. Sgrignani, J. Roda, G. Cavalli, A. Villa, S. Grazioso, G.
  in Pharmaceutics (2023) Vol.15 pp
  
• Myc controls NK cell development, IL-15-driven expansion, and translational machinery
  Khameneh, H. J. Fonta, N. Zenobi, A. Niogret, C. Ventura, P. Guerra, C. Kwee, I. Rinaldi, A. Pecoraro, M. Geiger, R. Cavalli, A. Bertoni, F. Vivier, E. Trumpp, A. Guarda, G.
  in Life Sci Alliance (2023) Vol.6 ppe202302069.
  
• Heterologous inactivated virus/mRNA vaccination response to BF.7, BQ.1.1, and XBB.1
  Zuo, F. Sun, R. Abolhassani, H. Du, L. Wang, Y. Vlachiotis, S. Bertoglio, F. Schubert, M. Rezaei, N. Chavoshzadeh, Z. Guerra, C. Cavalli, A. Andrell, J. Kumagai-Braesch, M. Xue, Y. Cao, Y. Hust, M. Robbiani, D. F. Xie, X. S. Hammarstrom, L. Marcotte, H. Pan-Hammarstrom, Q.
  in Lancet Reg Health West Pac (2023) Vol.33 pp100762
  
• Esmethadone-HCl (REL-1017): a promising rapid antidepressant
  Fava, M. Stahl, S. M. De Martin, S. Mattarei, A. Bettini, E. Comai, S. Alimonti, A. Bifari, F. Pani, L. Folli, F. Guidetti, C. Furlan, A. Sgrignani, J. Locatelli, P. Cavalli, A. O'Gorman, C. Traversa, S. Inturrisi, C. E. Pappagallo, M. Manfredi, P. L.
  in Eur Arch Psychiatry Clin Neurosci (2023) Vol. pp
  
• Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course
  Muri, J. Cecchinato, V. Cavalli, A. Shanbhag, A. A. Matkovic, M. Biggiogero, M. Maida, P. A. Moritz, J. Toscano, C. Ghovehoud, E. Furlan, R. Barbic, F. Voza, A. De Nadai, G. Cervia, C. Zurbuchen, Y. Taeschler, P. Murray, L. A. Danelon-Sargenti, G. Moro, S. Gong, T. Piffaretti, P. Bianchini, F. Crivelli, V. Podesvova, L. Pedotti, M. Jarrossay, D. Sgrignani, J. Thelen, S. Uhr, M. Bernasconi, E. Rauch, A. Manzo, A. Ciurea, A. Rocchi, M. B. L. Varani, L. Moser, B. Bottazzi, B. Thelen, M. Fallon, B. A. Boyman, O. Mantovani, A. Garzoni, C. Franzetti-Pellanda, A. Uguccioni, M. Robbiani, D. F.
  in Nat Immunol (2023) Vol.24 pp604-611.
  
• Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein
  Bianchini, F. Crivelli, V. Abernathy, M. E. Guerra, C. Palus, M. Muri, J. Marcotte, H. Piralla, A. Pedotti, M. De Gasparo, R. Simonelli, L. Matkovic, M. Toscano, C. Biggiogero, M. Calvaruso, V. Svoboda, P. Cervantes Rincon, T. Fava, T. Podesvova, L. Shanbhag, A. A. Celoria, A. Sgrignani, J. Stefanik, M. Honig, V. Pranclova, V. Michalcikova, T. Prochazka, J. Guerrini, G. Mehn, D. Ciabattini, A. Abolhassani, H. Jarrossay, D. Uguccioni, M. Medaglini, D. Pan-Hammarstrom, Q. Calzolai, L. Fernandez, D. Baldanti, F. Franzetti-Pellanda, A. Garzoni, C. Sedlacek, R. Ruzek, D. Varani, L. Cavalli, A. Barnes, C. O. Robbiani, D. F.
  in Sci Immunol (2023) Vol. ppeade0958
  
• A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity
  Roehlen, N. Saviano, A. El Saghire, H. Crouchet, E. Nehme, Z. Del Zompo, F. Juhling, F. Oudot, M. A. Durand, S. C. Duong, F. H. T. Cherradi, S. Gonzalez Motos, V. Almeida, N. Ponsolles, C. Heydmann, L. Ostyn, T. Lallement, A. Pessaux, P. Felli, E. Cavalli, A. Sgrignani, J. Thumann, C. Koutsopoulos, O. Fuchs, B. C. Hoshida, Y. Hofmann, M. Vyberg, M. Viuff, B. M. Galsgaard, E. D. Elson, G. Toso, A. Meyer, M. Iacone, R. Schweighoffer, T. Teixeira, G. Moll, S. De Vito, C. Roskams, T. Davidson, I. Heide, D. Heikenwalder, M. Zeisel, M. B. Lupberger, J. Mailly, L. Schuster, C. Baumert, T. F.
  in Sci Transl Med (2022) Vol.14 ppeabj4221
  
• CEMIP (HYBID, KIAA1199): Structure, function and expression in health and disease
  Spataro, S. Guerra, C. Cavalli, A. Sgrignani, J. Sleeman, J. Poulain, L. Boland, A. Scapozza, L. Moll, S. Prunotto, M.
  in FEBS J (2022) Vol.290 pp3946-3962
  
• Pharmacological Comparative Characterization of REL-1017 (Esmethadone-HCl) and Other NMDAR Channel Blockers in Human Heterodimeric N-Methyl-D-Aspartate Receptors
  Bettini, E. Stahl, S. M. De Martin, S. Mattarei, A. Sgrignani, J. Carignani, C. Nola, S. Locatelli, P. Pappagallo, M. Inturrisi, C. E. Bifari, F. Cavalli, A. Alimonti, A. Pani, L. Fava, M. Traversa, S. Folli, F. Manfredi, P. L.
  in Pharmaceuticals (Basel) (2022) Vol.15 pp
  
• Discovery of anti-Formin-like 1 protein (FMNL1) antibodies in membranous nephropathy and other glomerular diseases
  Bruschi, M. Cavalli, A. Moll, S. Candiano, G. Scapozza, L. Patel, J. J. Tan, J. C. Lo, K. C. Angeletti, A. Ghiggeri, G. M. Prunotto, M.
  in Sci Rep (2022) Vol.12 pp13659
  
• Reply to: Hultstrom et al., Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19. Mannose-binding lectin genetics in COVID-19
  Asselta, R. Paraboschi, E. M. Stravalaci, M. Invernizzi, P. Bonfanti, P. Biondi, A. Pagani, I. Pedotti, M. Doni, A. Scavello, F. Mapelli, S. N. Sironi, M. Perucchini, C. Varani, L. Matkovic, M. Cavalli, A. Cesana, D. Gallina, P. Pedemonte, N. Capurro, V. Clementi, N. Mancini, N. Bayarri-Olmos, R. Garred, P. Rappuoli, R. Duga, S. Bottazzi, B. Uguccioni, M. Vicenzi, E. Mantovani, A. Garlanda, C.
  in Nat Immunol (2022) Vol.23 pp865-867
  
• Focused Design of Novel Cyclic Peptides Endowed with GABARAP-Inhibiting Activity
  Fassi, E. M. A. Garofalo, M. Sgrignani, J. Dei Cas, M. Mori, M. Roda, G. Cavalli, A. Grazioso, G.
  in Int J Mol Sci (2022) Vol.23 pp
  
• GPCR Inhibition in Treating Lymphoma
  Barreca, M. Spano, V. Raimondi, M. V. Bivacqua, R. Giuffrida, S. Montalbano, A. Cavalli, A. Bertoni, F. Barraja, P.
  in Acs Medicinal Chemistry Letters (2022) Vol.13 pp358-364
  
• Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules
  Stravalaci, M. Pagani, I. Paraboschi, E. M. Pedotti, M. Doni, A. Scavello, F. Mapelli, S. N. Sironi, M. Perucchini, C. Varani, L. Matkovic, M. Cavalli, A. Cesana, D. Gallina, P. Pedemonte, N. Capurro, V. Clementi, N. Mancini, N. Invernizzi, P. Bayarri-Olmos, R. Garred, P. Rappuoli, R. Duga, S. Bottazzi, B. Uguccioni, M. Asselta, R. Vicenzi, E. Mantovani, A. Garlanda, C.
  in Nat Immunol (2022) Vol.23 pp275-286
  
• Management of transthyretin amyloidosis
  Condoluci A. , Théaudin, M., Schwotzer, R. , Pazhenkottil, A. P. , Arosio, P., Averaimo, M. , Bacher, U. , Bode, P. , Cavalli, A. , Dirnhofer, S. , Djerbi, N. , Dobner, S. , Fehr, T. , Garofalo, M. , Gaspert, A. , Gerull, S. , Heimgartner, R. , Hübers, A. , Jung, H. H. , Kessler, C. , Knöpfel, R. , Laptseva, N. , Magini, G. , Manka, R. , Mazzucchelli, L., Meyer, M. , Mihaylova, V. , Monney, P. , Mylonas, A. , Nkoulou, R. , Pabst, T. , Pfister, O. , Rüfer. A. , Schmidt, A., Seeger, H. , Stämpfli, S. H. , Stirnimann, G. , Suter, T. , Treglia, G. , Tzankov, A. , Vetter, F. , Zweier, M. , Flammer, A. J. , Gerber, B.
  in Swiss Med Wkly (2021) Vol.151 ppw30053
  
• Systematic Development of Peptide Inhibitors Targeting the CXCL12/HMGB1 Interaction
  Sgrignani, J. Cecchinato, V. Fassi, E. M. A. D'Agostino, G. Garofalo, M. Danelon, G. Pedotti, M. Simonelli, L. Varani, L. Grazioso, G. Uguccioni, M. Cavalli, A.
  in J Med Chem (2021) Vol.64 pp13439-13450.
  
• Compounds targeting OSBPL7 increase ABCA1-dependent cholesterol efflux preserving kidney function in two models of kidney disease
  Wright, M. B. Varona Santos, J. Kemmer, C. Maugeais, C. Carralot, J. P. Roever, S. Molina, J. Ducasa, G. M. Mitrofanova, A. Sloan, A. Ahmad, A. Pedigo, C. Ge, M. Pressly, J. Barisoni, L. Mendez, A. Sgrignani, J. Cavalli, A. Merscher, S. Prunotto, M. Fornoni, A.
  in Nat Commun (2021) Vol.12 pp4662
  
• EZH2-induced lysine K362 methylation enhances TMPRSS2-ERG oncogenic activity in prostate cancer
  Zoma, M. Curti, L. Shinde, D. Albino, D. Mitra, A. Sgrignani, J. Mapelli, S. N. Sandrini, G. Civenni, G. Merulla, J. Chiorino, G. Kunderfranco, P. Cacciatore, A. Kokanovic, A. Rinaldi, A. Cavalli, A. Catapano, C. V. Carbone, G. M.
  in Nat Commun (2021) Vol.12 pp4147
  
• Machine learning analyses of antibody somatic mutations predict immunoglobulin light chain toxicity
  Garofalo, M. Piccoli, L. Romeo, M. Barzago, M. M. Ravasio, S. Foglierini, M. Matkovic, M. Sgrignani, J. De Gasparo, R. Prunotto, M. Varani, L. Diomede, L. Michielin, O. Lanzavecchia, A. Cavalli, A.
  in Nature Communications (2021) Vol.12 pp3532
  
• Glomerular Macrophages in Human Auto- and Allo-Immune Nephritis
  Moll, S. Angeletti, A. Scapozza, L. Cavalli, A. Ghiggeri, G. M. Prunotto, M.
  in Cells (2021) Vol.10 pp603
  
• Computational identification of a putative allosteric binding pocket in TMPRSS2
  Sgrignani, J. and Cavalli, A.
  in Front. Mol. Biosci. (2021) Vol.8 pp666626
  
• Expert recommendation from the Swiss Amyloidosis Network (SAN) for systemic AL-amyloidosis
  Schwotzer, R. Flammer, A. J. Gerull, S. Pabst, T. Arosio, P. Averaimo, M. Bacher, V. U. Bode, P. Cavalli, A. Concoluci, A. Dirnhofer, S. Djerbi, N. Dobner, S. W. Fehr, T. Garofalo, M. Gaspert, A. Heimgartner, R. Hubers, A. Jung, H. H. Kessler, C. Knopfel, R. Laptseva, N. Manka, R. Mazzucchelli, L. Meyer, M. Mihaylova, V. Monney, P. Mylonas, A. Nkoulou, R. Pazhenkottil, A. Pfister, O. Rufer, A. Schmidt, A. Seeger, H. Stampfli, S. F. Stirnimann, G. Suter, T. Theaudin, M. Treglia, G. Tzankov, A. Vetter, F. Zweier, M. Gerber, B.
  in Swiss Med Wkly (2020) Vol.150 ppw20364
  
• Androgen-deprivation therapies for prostate cancer and risk of infection by SARS-CoV-2: a population-based study (N = 4532)
  Montopoli, M. Zumerle, S. Vettor, R. Rugge, M. Zorzi, M. Catapano, C. V. Carbone, G. M. Cavalli, A. Pagano, F. Ragazzi, E. Prayer-Galetti, T. Alimonti, A.
  in Ann Oncol (2020) Vol.31 pp1040-1045
  
• How Computational Chemistry and Drug Delivery Techniques Can Support the Development of New Anticancer Drugs
  Garofalo, M. Grazioso, G. Cavalli, A.
  in Molecules (2020) Vol.25 pppii: E1756
  
• Endoplasmic Reticulum and Lysosomal Quality Control of Four Nonsense Mutants of Iduronate 2-Sulfatase Linked to Hunter’s Syndrome
  Marazza, A. Galli, C. Fasana, E. Burda, P. Fassi, E. M. A. Baumgartner, M. Cavalli, A. Molinari, M.
  in DNA Cell Biol (2020) Vol.39 pp226-234
  
• Zinc(ii)-mediated diastereoselective Passerini reactions of biocatalytically desymmetrised renewable inputs
  Moni, L. Banfi, L. Cartagenova, D. Cavalli, A. Lambruschini, C. Martino, E. Orru, R. V. A. Ruijter, E. Saya, J. M. Sgrignani, J. Riva, R.
  in Organic Chemistry Frontiers (2019) Vol. pp
  
• Oxidation State Dependent Conformational Changes of HMGB1 Regulate the Formation of the CXCL12/HMGB1 Heterocomplex
  V. Fassi, E. M. A. Sgrignani, J. D'Agostino, V. Cecchinato, G. Garofalo, M. Grazioso, G. Uguccioni, M. Cavalli, A.
  in Comput Struct Biotechnol J (2019) Vol.17 pp886-894
  
• The ETS Inhibitors YK-4-279 and TK-216 Are Novel Antilymphoma Agents
  Spriano, F. Chung, E. Y. L. Gaudio, E. Tarantelli, C. Cascione, L. Napoli, S. Jessen, K. Carrassa, L. Priebe, V. Sartori, G. Graham, G. Selvanathan, S. P. Cavalli, A. Rinaldi, A. Kwee, I. Testoni, M. Genini, D. Ye, B. H. Zucca, E. Stathis, A. Lannutti, B. Toretsky, J. A. Bertoni, F.
  in Clin Cancer Res (2019) Vol.25 pp5167-5176
  
• The first‐in‐class ETS inhibitor TK‐216 interferes with ETS transcription factors and synergize with lenalidomide in lymphoma
  Spriano, F. Chung,E. Napoli, S. Gaudio, E. Cascione, L. Cavalli, A. Rinaldi, A. Kwee, I. Ye, H. Rossi, D. Zucca, E. Stathis, A. Jessen, K. Lannutti, B. Toretsky, J. Bertoni, F.
  in Hematological Oncology (2019) Vol.37 pp322
  
• DDR1 role in fibrosis and its pharmacological targeting
  Moll, S. Desmouliere, A. Moeller, M. J. Badi, L. Arcadu, F. Richter, H. Satz, A. Uhles, S. Cavalli, A. Drawnel, F. Scapozza, L. Prunotto, M.
  in Biochim Biophys Acta Mol Cell Res (2019) Vol.1866 pp118474
  
• How phosphorylation influences E1 subunit pyruvate dehydrogenase: A computational study
  Sgrignani, J. Chen, J. Alimonti, A. Cavalli, A.
  in Sci Rep (2018) Vol.8 pp14683
  
• Enhancing coevolution-based contact prediction by imposing structural self-consistency of the contacts
  Kassem, M. M. Christoffersen, L. B. Cavalli, A.
  in Sci Rep (2018) Vol.8 pp11112
  
• Structural Biology of STAT3 and Its Implications for Anticancer Therapies Development
  Sgrignani, J Garofalo, M Matkovic, M Catapano, C. V. Cavalli, A.
  in Int. J. Mol. Sci. (2018) Vol.19 pp1591
  
• A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential
  Wang, J. Bardelli, M. Espinosa, D. A. Pedotti, M. Ng, T. S. Bianchi, S. Simonelli, L. Lim, E. X. Y. Foglierini, M. Zatta, F. Jaconi, S. Beltramello, M. Cameroni, E. Fibriansah, G. Shi, J. Barca, T. Pagani, I. Rubio, A. Broccoli, V. Vicenzi, E. Graham, V. Pullan, S. Dowall, S. Hewson, R. Jurt, S. Zerbe, O. Stettler, K. Lanzavecchia, A. Sallusto, F. Cavalli, A. Harris, E. Lok, S. M. Varani, L. Corti, D.
  in Cell (2017) Vol.171 pp229-241 e15
  
• Single or Multiple Access Channels to the CYP450s Active Site? an Answer from Free Energy Simulations of the Human Aromatase Enzyme
  Magistrato, A. Sgrignani, J. Krause, R. Cavalli, A.
  in J Phys Chem Lett (2017) Vol.8 pp2036-2042
  
• The Dynamic Basis for Signal Propagation in Human Pin1-WW
  Olsson, S. Strotz, D. Vogeli, B. Cavalli, A.
  in Structure (2016) Vol.24 pp1464-75
  S. Olsson and A. Cavalli are co-corresponding authors.
• Enzymatic and Inhibition Mechanism of Human Aromatase (CYP19A1) Enzyme. A Computational Perspective from QM/MM and Classical Molecular Dynamics Simulations
  Sgrignani, J. Cavalli, A. Colombo, G.
  in Mini Rev Med Chem (2016) Vol.16 pp1112-24
  
• Metainference: A Bayesian inference method for heterogeneous systems
  Bonomi, M. Camilloni, C. Cavalli, A.
  in Science Advances (2016) Vol.2 ppe1501177
  
• Molecular Determinants for Unphosphorylated STAT3 Dimerization Determined by Integrative Modeling
  Sgrignani, J. Olsson, S. Ekonomiuk, D. Krause, R. Catapano, C. V. Cavalli, A.
  in Biochemistry (2015) Vol.54 pp5489-501
  
• Quantification of Entropy-Loss in Replica-Averaged Modeling
  Olsson, S. Cavalli, A.
  in J Chem Theory Comput (2015) Vol.11 pp3973-7
  
• Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution
  Brewer, K. D. Bacaj, T. Cavalli, A. Swarbrick, J. D. Liu, J. Zhou, A. Zhou, P. Barlow, N. Xu, J. Seven, A. B. Prinslow, E. A. Voleti, R. Haussinger, D. Bonvin, A. M. Tomchick, D. R. Vendruscolo, M. Graham, B. Sudhof, T. C. Rizo, J.
  in Nat Struct Mol Biol (2015) Vol.22 pp555-64
  
• Molecular Dynamics of Biomolecules through Direct Analysis of Dipolar Couplings
  Olsson, S. Ekonomiuk, D. Sgrignani, J. Cavalli, A.
  in J Am Chem Soc (2015) Vol.137 pp6270-8
  
• Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer
  Chen, J. Guccini, I. Mitri, D. D. Revandkar, A. Sarti, M. Pasquini, E. Alajati, A. Pinton, S. Losa, M. Civenni, G. Catapano, C. V. Sgrignani, J. Cavalli, A. D'Antuono, R. Asara, J. M. Morandi, A. Chiarugi, P. Crotti, S. Agostini, M. Montopoli, M. Masgras, I. Rasola, A. Garcia-Escudero, R. Delaleu, N. Rinaldi, A. Bertoni, F. Bono, J. Carracedo, A. Alimonti, A.
  in Nat Genet (2015) Vol.50 pp219-228
  
• Characterization of the Conformational Fluctuations in the Josephin Domain of Ataxin-3
  Sanfelice, D. De Simone, A. Cavalli, A. Vendruscolo, M. Pastore, A.
  in Biophys J (2014) Vol.107 pp2923-2931
  
• A probabilistic approach to the determination of native state ensembles of proteins
  Olsson, S. Vögeli, B.R. Cavalli, A. Ferkinghoff-Borg, J. Lindorff-Larsen, K. Hamelryck, T.
  in J. Chem. Theory Comput. (2014) Vol.10 pp3484-3491
  
• Archaeal MBF1 binds to 30S and 70S ribosomes via its helix-turn-helix domain
  Blombach, F. Launay, H. Snijders, A. P. Wu, H. de Koning, B. Brouns, S. J. Ettema, T. Camilloni, C. Cavalli, A. Vendruscolo, M. Dickman, M. J. Cabrita, L. D. La Teana, A. Benelli, D. Londei, P. Christodoulou, J. van der Oost, J.
  in Biochem J (2014) Vol. pp
  
• ALMOST: An all atom molecular simulation toolkit for protein structure determination
  Fu, B. Sahakyan, A. B. Camilloni, C. Paci, E. Caflisch, A. Vendruscolo, M. Cavalli, A.
  in J Comput Chem (2014) Vol.35 pp1101-5
  
• Determination of the individual roles of the linker residues in the interdomain motions of calmodulin using NMR chemical shifts
  Kukic, P. Camilloni, C. Cavalli, A.
  in J Mol Biol (2014) Vol.426 pp1826-38
  
• A conformational ensemble derived using NMR methyl chemical shifts reveals a mechanical clamping transition that gates the binding of the HU protein to DNA
  Kannan, A. Camilloni, C. Sahakyan, A. B. Cavalli, A. Vendruscolo, M.
  in J Am Chem Soc (2013) Vol.136 pp2204-7
  
• Replica-Averaged Metadynamics
  Camilloni, C. Cavalli, A. Vendruscolo, M.
  in J. Chem. Theory Comput. (2013) Vol.12 pp5610-17
  
• Molecular dynamics simulations with replica-averaged structural restraints generate structural ensembles according to the maximum entropy principle
  Cavalli, A. Camilloni, C. Vendruscolo, M.
  in J Chem Phys (2013) Vol.138 pp094112
  
• Assessment of the use of NMR chemical shifts as replica-averaged structural restraints in molecular dynamics simulations to characterize the dynamics of proteins
  Camilloni, C. Cavalli, A. Vendruscolo, M.
  in J Phys Chem B (2013) Vol.117 pp1838-43
  
• MYD88 somatic mutations in MALT lymphomas
  Li, Z. M. Rinaldi, A. Cavalli, A. Ponzoni, M. Gascoyne, R. D. Bhagat, G. Zucca, E. Bertoni, F.
  in Br J Haematol (2012) Vol.158 pp662-4
  
• Structure of an intermediate state in protein folding and aggregation
  Neudecker, P. Robustelli, P. Cavalli, A. Lundstrom, P. Zarrine-Afsar, A. Sharpe, S. Vendruscolo, M. Kay, L. E.
  in Science (2012) Vol.336 pp362-6
  
• Protein Structure Validation Using Side-Chain Chemical Shifts
  Sahakyan, A. B. Cavalli, A. Vranken, W. F.
  in J Phys Chem B (2012) Vol. pp
  
• Characterization of the conformational equilibrium between the two major substates of RNase A using NMR chemical shifts
  Camilloni, C. Robustelli, P. De Simone, A. Cavalli, A. Vendruscolo, M.
  in J Am Chem Soc (2012) Vol.134 pp3968-71
  
• Blind testing of routine, fully automated determination of protein structures from NMR data
  Rosato, A. Aramini, J. M. Arrowsmith, C. Baker, D. Cavalli, A. Doreleijers, J. F. Eletsky, A. Giachetti, A. Guerry, P. Gutmanas, A. Guntert, P. He, Y. Herrmann, T. Huang, Y. J. Jaravine, V. Jonker, H. R. Kennedy, M. A. Lange, O. F. Liu, G. Malliavin, T. E. Mani, R. Mao, B. Montelione, G. T. Nilges, M.Rossi, P. van der Schot, G. Schwalbe, H. Szyperski, T. A. Vendruscolo, M.
  in Structure (2012) Vol.20 pp227-36
  
• Using side-chain aromatic proton chemical shifts for a quantitative analysis of protein structures
  Sahakyan, A. B. Vranken, W. F. Cavalli, A.
  in Angew Chem Int Ed Engl (2011) Vol.50 pp9620-3
  
• Using chemical shifts to determine structural changes in proteins upon complex formation
  Cavalli, A. Montalvao, R. W. Vendruscolo, M.
  in J Phys Chem B (2011) Vol.115 pp9491-4
  
• Structure-based prediction of methyl chemical shifts in proteins
  Sahakyan, A. B. Vranken, W. F. Cavalli, A.
  in J Biomol NMR (2011) Vol.50 pp331-46
  
• Using NMR chemical shifts as structural restraints in molecular dynamics simulations of proteins
  Robustelli, P. Kohlhoff, K. Cavalli, A.
  in Structure (2010) Vol.18 pp923-33
  
• Insights into protein-protein and enzyme-substrate interactions in modular polyketide synthases
  Tran, L. Broadhurst, R. W. Tosin, M. Cavalli, A. Weissman, K. J.
  in Chem Biol (2010) Vol.17 pp705-16
  
• Accurate random coil chemical shifts from an analysis of loop regions in native states of proteins
  De Simone, A. Cavalli, A. Hsu, S. T. Vendruscolo, M.
  in J Am Chem Soc (2009) Vol.131 pp16332-3
  
• Fast and accurate predictions of protein NMR chemical shifts from interatomic distances
  Kohlhoff, K. J. Robustelli, P. Cavalli, A. Vendruscolo, M.
  in J Am Chem Soc (2009) Vol.131 pp13894-5
  
• CASD-NMR: critical assessment of automated structure determination by NMR
  Rosato, A. Bagaria, A. Baker, D. Cavalli, A. Doreleijers, J. F. Giachetti, A. Guerry, P. Guntert, P. Herrmann, T. Huang, Y. J. Jonker, H. R. Mao, B. Malliavin, T. E. Montelione, G. T. Nilges, M. Raman, S. van der Schot, G. Vranken, W. F. Vuister, G. W. Bonvin, A. M.
  in Nat Methods (2009) Vol.6 pp625-6
  
• Folding of small proteins by Monte Carlo simulations with chemical shift restraints without the use of molecular fragment replacement or structural homology
  Robustelli, P. Cavalli, A. Dobson, C. M. Salvatella, X.
  in J Phys Chem B (2009) Vol.113 pp7890-6
  
• Determination of protein structures in the solid state from NMR chemical shifts
  Robustelli, P. Cavalli, A. Vendruscolo, M.
  in Structure (2008) Vol.16 pp1764-9
  
• Structure determination of protein-protein complexes using NMR chemical shifts: case of an endonuclease colicin-immunity protein complex
  Montalvao, R. W. Cavalli, A. Salvatella, X. Vendruscolo, M.
  in J Am Chem Soc (2008) Vol.130 pp15990-6
  
• Identification of aggregation-prone elements by using interaction-energy matrices
  Bui, J. M. Cavalli, A. Gsponer, J.
  in Angew Chem Int Ed Engl (2008) Vol.47 pp7267-9
  
• A coupled equilibrium shift mechanism in calmodulin-mediated signal transduction
  Gsponer, J. Christodoulou, J. Cavalli, A. Richter, B. Dobson, C. M. Vendruscolo, M.
  in Structure (2008) Vol.16 pp736-46
  
• Protein structure determination from NMR chemical shifts
  Cavalli, A. Salvatella, X. Dobson, C. M.
  in Proc Natl Acad Sci U S A (2007) Vol.104 pp9615-20
  
• Prediction of local structural stabilities of proteins from their amino acid sequences
  Tartaglia, G. G. Cavalli, A. Vendruscolo, M.
  in Structure (2007) Vol.15 pp139-43
  
• Geometry, energetics, and dynamics of hydrogen bonds in proteins: structural information derived from NMR scalar couplings
  Gsponer, J. Hopearuoho, H. Cavalli, A. Vendruscolo, M.
  in J Am Chem Soc (2006) Vol.128 pp15127-35
  
• Organism complexity anti-correlates with proteomic beta-aggregation propensity
  Tartaglia, G. G. Pellarin, R. Cavalli, A.
  in Protein Sci (2005) Vol.14 pp2735-40
  
• Prediction of aggregation rate and aggregation-prone segments in polypeptide sequences
  Tartaglia, G. G. Cavalli, A. Pellarin, R.
  in Protein Sci (2005) Vol.14 pp2723-34
  
• Comparison of sequence-based and structure-based energy functions for the reversible folding of a peptide
  Cavalli, A. Vendruscolo, M. Paci, E.
  in Biophys J (2005) Vol.88 pp3158-66
  
• The role of aromaticity, exposed surface, and dipole moment in determining protein aggregation rates
  Tartaglia, G. G. Cavalli, A. Pellarin, R.
  in Protein Sci (2004) Vol.13 pp1939-41
  
• Fast protein folding on downhill energy landscape
  Cavalli, A. Haberthur, U. Paci, E.
  in Protein Sci (2003) Vol.12 pp1801-3
  
• Analysis of the distributed computing approach applied to the folding of a small beta peptide
  Paci, E. Cavalli, A. Vendruscolo, M.
  in Proc Natl Acad Sci U S A (2003) Vol.100 pp8217-22
  
• Weak temperature dependence of the free energy surface and folding pathways of structured peptides
  Cavalli, A. Ferrara, P. Caflisch, A.
  in Proteins (2002) Vol.47 pp305-14