The facility provides state-of-the-art imaging equipment and expertise for the most demanding research projects from subcellular events to cell dynamics in organs. We also offer support and courses for students and researchers.
With these systems, we can perform most cell and tissue imaging procedures, such as STED, fast live cell imaging, FRAP, photoconversion, FLIM-FRET, and 3D reconstruction on unclarified and clarified tissues. Images with these techniques can also be combined with Electron Microscopy micrographs in Correlative Electron Microscopy (CLEM).
LysoQuant is a deep learning approach for the automatic segmentation and classification of fluorescent images capturing cargo delivery within endolysosomes.
Initially designed for the needs of a research group at the Institute, it has been published in Molecular Biology of the Cell and is available for download.