Publications - IRB USI

Publications

Immunomolecular and reactivity landscapes of gut IgA subclasses in homeostasis and inflammatory bowel disease
Tejedor Vaquero, S. Neuman, H. Comerma, L. Marcos-Fa, X. Corral-Vazquez, C. Uzzan, M. Pybus, M. Segura-Garzon, D. Guerra, Jo. Perruzza, L. Tacho-Pinot, R. Sintes, J. Rosenstein, A. Grasset, E. K. Iglesias, M. Gonzalez Farre, M. Lop, J. Patriaca-Amiano, M. E. Larrubia-Loring, M. Santiago-Diaz, P. Perera-Bel, J. Berenguer-Molins, P. Martinez Gallo, M. Martin-Nalda, A. Varela, E. Garrido-Pontnou, M. Grassi, F. Guarner, F. Mehandru, S. Marquez-Mosquera, L. Mehr, R. Cerutti, A. Magri, G.
in J Exp Med (2024) Vol.221 pp
A first-in-class Wiskott-Aldrich syndrome protein activator with antitumor activity in hematologic cancers
Spriano, F. Sartori, G. Sgrignani, J. Barnabei, L. Arribas, A. J. Guala, M. Del Amor, A. M. C. Tomasso, M. R. Tarantelli, C. Cascione, L. Golino, G. Riveiro, M. E. Bortolozzi, R. Lupia, A. Paduano, F. Huguet, S. Rezai, K. Rinaldi, A. Margheriti, F. Ventura, P. Guarda, G. Costa, G. Rocca, R. Furlan, A. Verdonk, L. M. Innocenti, P. Martin, N. I. Viola, G. Driessen, C. Zucca, E. Stathis, A. Gahtory, D. Van den Nieuwboer, M. Bornhauser, B. Alcaro, S. Trapasso, F. Cristobal, S. Padrick, S. B. Pazzi, N. Cavalli, F. Cavalli, A. Gaudio, E. Bertoni, F.
in Haematologica (2024) Vol.109 pp3602-3614
Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes
Rudinskiy, M. Morone, D. Molinari, M.
in Traffic (2024) Vol.25 ppe12957
SARS-CoV-2 mRNA vaccines do not worsen autoimmunity in patients with autoimmune liver diseases
Kalin, T. Passarin, K. Filipowic-Sinnreich, M. Semela, D. Seifert, T. Sallusto, F. Vergani, D. Cerny, A. Mieli-Vergani, G. Terziroli Beretta-Piccoli, B. Swiss Autoimmune Hepatitis Cohort, Study Swiss Primary Biliary Cholangitis Cohort, Study Swiss Primary Sclerosing Cholangitis, Study
in J Autoimmun (2024) Vol.149 pp103325
International Union of Basic and Clinical Pharmacology. CXVIII. Update on the Nomenclature for Atypical Chemokine Receptors including ACKR5
Chevigne, A. Legler, D. F. Rot, A. Sozzani, S. Szpakowska, M. Thelen, M.
in Pharmacol Rev (2024) Vol. pp
PI3Kdelta activation, IL6 overexpression, and CD37 loss cause resistance to naratuximab emtansine in lymphomas
Arribas, A. J. Napoli, S. Gaudio, E. Herbaux, C. Cannas, E. Tarantelli, C. Bordone Pittau, R. Cascione, L. Munz, N. Aresu, L. Sgrignani, J. Rinaldi, A. Kwee, I. Rossi, D. Cavalli, A. Zucca, E. Stussi, G. Stathis, A. Sloss, C. Davids, M. S. Bertoni, F.
in Blood Adv (2024) Vol. pp
Postnatal supplementation with alarmins S100a8/a9 ameliorates malnutrition-induced neonate enteropathy in mice
Perruzza, L. Heckmann, J. Rezzonico Jost, T. Raneri, M. Guglielmetti, S. Gargari, G. Palatella, M. Willers, M. Fehlhaber, B. Werlein, C. Vogl, T. Roth, J. Grassi, F. Viemann, D.
in Nat Commun (2024) Vol.15 pp8623
TMX5/TXNDC15, a natural trapping mutant of the PDI family is a client of the proteostatic factor ERp44
Solda, T. Galli, C. Guerra, C. Hoefner, C. Molinari, M.
in Life Sci Alliance (2024) Vol.7 pp
Autoantibodies neutralizing type I IFNs underlie severe tick-borne encephalitis in approximately 10% of patients
Gervais, A. Marchal, A. Fortova, A. Berankova, M. Krbkova, L. Pychova, M. Salat, J. Zhao, S. Kerrouche, N. Le Voyer, T. Stiasny, K. Raffl, S. Schieber Pachart, A. Fafi-Kremer, S. Gravier, S. Robbiani, D. F. Abel, L. MacDonald, M. R. Rice, C. M. Weissmann, G. Kamal Eldin, T. Robatscher, E. Erne, E. M. Pagani, E. Borghesi, A. Puel, A. Bastard, P. Velay, A. Martinot, M. Hansmann, Y. Aberle, J. H. Ruzek, D. Cobat, A. Zhang, S. Y. Casanova, J. L.
in J Exp Med (2024) Vol.221 pp
Exploration of isatin-based inhibitors of SARS-CoV-2 Nsp15 endoribonuclease
Rampias, T. Antoniou, T. Stevaert, A. Kravariti, L. Van Loy, B. Vandeput, J. Sgrignani, J. Filippidou, N. Locatelli, P. Samiotaki, M. Tzakos, E. P. Cavalli, A. Naesens, L. Sideris, D. C. Tzakos, A. G.
in Eur J Med Chem (2024) Vol.279 pp116886
Mechanism of BRCA1-BARD1 function in DNA end resection and DNA protection
Ceppi, I. Dello Stritto, M. R. Mutze, M. Braunshier, S. Mengoli, V. Reginato, G. Vo, H. M. P. Jimeno, S. Acharya, A. Roy, M. Sanchez, A. Halder, S. Howard, S. M. Guerois, R. Huertas, P. Noordermeer, S. M. Seidel, R. Cejka, P.
in Nature (2024) Vol.634 pp492-500
Exploring the removal of Spo11 and topoisomerases from DNA breaks in S. cerevisiae by human Tyrosyl DNA Phosphodiesterase 2
Johnson, D. Allison, R. M. Cannavo, E. Cejka, P. Harper, J. A. Neale, M. J.
in DNA Repair (Amst) (2024) Vol.142 pp103757
Sae2 controls Mre11 endo- and exonuclease activities by different mechanisms
Tamai, T. Reginato, G. Ojiri, R. Morita, I. Avrutis, A. Cejka, P. Shinohara, M. Sugimoto, K.
in Nat Commun (2024) Vol.15 pp7221
Stealth mRNA nanovaccines to control lymph node trafficking
Garcia-Fernandez, C. Virgilio, T. Latino, I. Guerra-Rebollo, M. Gonzalez, S. F. Borros, S. Fornaguera, C.
in J Control Release (2024) Vol.374 pp325-336
HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability
Bai, G. Endres, T. Kuhbacher, U. Mengoli, V. Greer, B. H. Peacock, E. M. Newton, M. D. Stanage, T. Dello Stritto, M. R. Lungu, R. Crossley, M. P. Sathirachinda, A. Cortez, D. Boulton, S. J. Cejka, P. Eichman, B. F. Cimprich, K. A.
in Mol Cell (2024) Vol.84 pp3044-3060.
Persistent longitudinal T cell responses after SARS-CoV-2 mRNA vaccines in MS patients on different disease modifying treatments
Disanto, G. Galante, A. Sacco, R. Mallucci, G. Mele, F. Sallusto, F. Zecca, C. Gobbi, C.
in Mult Scler Relat Disord (2024) Vol.90 pp105813
NLRC5: back to innate immunity
Guerra, J. Guarda, G.
in Trends Immunol (2024) Vol.45 pp571-573
Site-specific serology unveils cross-reactive monoclonal antibodies targeting influenza A hemagglutinin epitopes
Paparoditis, P. C. G. Fruehwirth, A. Bevc, K. Low, J. S. Jerak, J. Terzaghi, L. Foglierini, M. Fernandez, B. Jarrossay, D. Corti, D. Sallusto, F. Lanzavecchia, A. Cassotta, A.
in Eur J Immunol (2024) Vol.54 ppe2451045
BACH2 regulates diversification of regulatory and proinflammatory chromatin states in T(H)17 cells
Thakore, P. I. Schnell, A. Huang, L. Zhao, M. Hou, Y. Christian, E. Zaghouani, S. Wang, C. Singh, V. Singaraju, A. Krishnan, R. K. Kozoriz, D. Ma, S. Sankar, V. Notarbartolo, S. Buenrostro, J. D. Sallusto, F. Patsopoulos, N. A. Rozenblatt-Rosen, O. Kuchroo, V. K. Regev, A.
in Nat Immunol (2024) Vol.25 pp1395-1410
HLTF disrupts Cas9-DNA post-cleavage complexes to allow DNA break processing
Reginato, G. Dello Stritto, M. R. Wang, Y. Hao, J. Pavani, R. Schmitz, M. Halder, S. Morin, V. Cannavo, E. Ceppi, I. Braunshier, S. Acharya, A. Ropars, V. Charbonnier, J. B. Jinek, M. Nussenzweig, A. Ha, T. Cejka, P.
in Nat Commun (2024) Vol.15 pp5789
A Menage a trois: NLRC5, immunity, and metabolism
Brunschwiler, F. Nakka, S. Guerra, J. Guarda, G.
in Front Immunol (2024) Vol.15 pp1426620
Targeting senescence induced by age or chemotherapy with a polyphenol-rich natural extract improves longevity and healthspan in mice
Zumerle, S. Sarill, M. Saponaro, M. Colucci, M. Contu, L. Lazzarini, E. Sartori, R. Pezzini, C. Rinaldi, A. Scanu, A. Sgrignani, J. Locatelli, P. Sabbadin, M. Valdata, A. Brina, D. Giacomini, I. Rizzo, B. Pierantoni, A. Sharifi, S. Bressan, S. Altomare, C. Goshovska, Y. Giraudo, C. Luisetto, R. Iaccarino, L. Torcasio, C. Mosole, S. Pasquini, E. Pellegrini, L. Peron, G. Fassan, M. Masiero, S. Giori, A. M. Dall'Acqua, S. Auwerx, J. Cippa, P. Cavalli, A. Bolis, M. Sandri, M. Barile, L. Montopoli, M. Alimonti, A.
in Nat Aging (2024) Vol.4 pp1231-1248
Protection from environmental enteric dysfunction and growth improvement in malnourished newborns by amplification of secretory IgA
Perruzza, L. Rezzonico Jost, T. Raneri, M. Gargari, G. Palatella, M. De Ponte Conti, B. Seehusen, F. Heckmann, J. Viemann, D. Guglielmetti, S. Grassi, F.
in Cell Rep Med (2024) Vol. pp101639
A first-in-class Wiskott-Aldrich syndrome protein activator with anti-tumor activity in hematologic cancers
Spriano, F. Sartori, G. Sgrignani, J. Barnabei, L. Arribas, A. J. Guala, M. Del Amor, A. M. C. Tomasso, M. R. Tarantelli, C. Cascione, L. Golino, G. Riveiro, M. E. Bortolozzi, R. Lupia, A. Paduano, F. Huguet, S. Rezai, K. Rinaldi, A. Margheriti, F. Ventura, P. Guarda, G. Costa, G. Rocca, R. Furlan, A. Verdonk, L. M. Innocenti, P. Martin, N. I. Viola, G. Driessen, C. Zucca, E. Stathis, A. Gahtory, D. Van den Nieuwboer, M. Bornhauser, B. Alcaro, S. Trapasso, F. Cristobal, S. Padrick, S. B. Pazzi, N. Cavalli, F. Cavalli, A. Gaudio, E. Bertoni, F.
in Haematologica (2024) Vol. pp
Structure and repair of replication-coupled DNA breaks
Pavani, R. Tripathi, V. Vrtis, K. B. Zong, D. Chari, R. Callen, E. Pankajam, A. V. Zhen, G. Matos-Rodrigues, G. Yang, J. Wu, S. Reginato, G. Wu, W. Cejka, P. Walter, J. C. Nussenzweig, A.
in Science (2024) Vol.385 ppeado3867

Istituto di Ricerca in Biomedicina

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