Denise Bottinelli Awarded PhD
on September 6, 2012 Denise Bottinelli successfully defended her PhD thesis, which was presented at the University of Lausanne, Switzerland. Her work entitled ” Evaluation of the early changes occurring in the draining lymph node upon subcutaneous stimulation” was performed in the laboratory of Mariagrazia Uguccioni. Denise’s supervisor at the University of Lausanne was Prof. […]
Discovery of the origin of the autoantibodies that cause pemphigus, a severe autoimmune disease
on September 5, 2012 A study conducted in close collaboration between the IRB and the Laboratory of Molecular and Cellular Biology at the Istituto Dermopatico dell’Immacolata (IDI), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) in Rome, led to the discovery of the origins of a serious autoimmune disease, the pemphigus. The research just […]
Zina Yudina Awarded PhD
on August 28, 2012 Zina Yudina successfully defended her PhD thesis at the Medway School of Pharmacy, University of Kent, UK. Her work entitled: “Structural basis of diphtheria toxin neutralization by human monoclonal antibodies” was performed in the laboratory of Luca Varani. Zina’s supervisor at the University of Kent was Prof. Alistair Mathie. Thesis […]
Nicole Rusca Awarded PhD
on July 12, 2012 Nicole Rusca successfully defended her PhD thesis, which was presented at the University of Basel. Her work entitled “MiR-146a: a key microRNA involved in regulating mast cell survival and T lymphocyte differentiation” was performed in the laboratory of Silvia Monticelli. Nicole’s supervisor at the University of Basel was Prof. Jean Pieters. […]
The scientific and annual reports 2011 are published
on June 28, 2012 The IRB scientific and annual reports for the year 2011 are published. They can be accessed at the following addresses: Scientific report: Scientific reports downloads Annual report: Annual reports downloads
A response to stress: the IRB dissects the mechanism
on June 20, 2012 The scientific journal Molecular Cell publishes in its issue of June 29 the results of a study conducted by the group of Professor Maurizio Molinari from the Institute for Research in Biomedicine (IRB), Bellinzona, made in collaboration with the group of Professor Fulvio Reggiori from the University Medical Center Utrecht. The […]
Dora Pinto Awarded PhD
on May 2, 2012 Dora Pinto successfully defended her PhD thesis, which was presented at the University Vita Salute San Raffaele, Milano, Italy. Her work entitled “Specificity, dynamics and novel properties of human plasma cells” was performed in the laboratory of Antonio Lanzavecchia. Dora’s supervisor at the University Vita Salute San Raffaele was Roberto Sitia. […]
The IRB is one of the grantees of the IMI JU-funded project ABIRISK
on April 17, 2012 ABIRISK Project Officially Started A growing number of medicines are based on biological molecules such as proteins and monoclonal antibodies. These novel drugs have resulted in new, more effective treatments for a number of serious conditions. Yet sometimes these medicines trigger a response from the patient’s immune system, which can […]
Discovered a switch that regulates inflammation, a study published in Nature
on April 2, 2012 The cells of the immune system possess powerful weapons that are able to fight off the invasion of microorganisms, yet at the same time can cause collateral damage. In particular, the Th17 lymphocytes, which carry this name because they produce interleukin-17, are important for the protection against fungi and bacteria but […]
Mechanism of migration of the inflammatory cells published in the Journal of Experimental Medicine
on March 22, 2012 During tissue damage, the protein of the alarmin family, HMGB1, released from the cells, was shown to be capable of attracting cells from the peripheral blood and to start the inflammatory process which can be either positive i.e., repair the damage or negative i.e., continue in a chronic inflammation. The mechanism […]
