Opening for Group Leader position at the IRB

The Institute for Research in Biomedicine (IRB) officially opened an international call for the recruitment of a new group leader (deadline December 1, 2022). We seek an outstanding scientist to complement the current research at the Institute while expanding to new research areas. The successful candidate will be an early- or mid-career scientist, who will […]
Jonathan Muri won the Poster Award 2022

September 8-11, 2022: Joint meeting of the Swiss Society for Allergology and Immunology (SSAI) and the International Immunocompromised Host Society (ICHS) at the Congress Center in Basel, Switzerland. Jonathan Muri won the Poster Award 2022 for the “Best Poster in Clinical Immunology” with the work on anti-chemokine antibodies after SARS-CoV-2 infection. The prize, sponsored by Biotest, […]
Secretory IgA promotes gut fitness

Secretory Immunoglobulin A (SIgA) is the antibody produced within mucosal membranes and is the most abundant antibody type synthesized in our body. In the intestine, SIgA possesses two antithetic functions acting either in preventing or promoting bacterial colonization. When the intestine is attacked by an invasive bacterium, a strongly polarized SIgA response ensures clustering of […]
T cell responses in heart Disease
Graduate School of Biomedical Sciences, Tufts University (Boston, US) Contact: Ddr. Santiago F. González Hybrid Conference
The thin line between pDC and cDC
Earl Statman Investigator at the National Institute of Dental and Craniofacial Research (NIDCR) Bethesda (US) Contact: Prof. Greta Guarda Date: 31.08.2022 2:00 pm Speakers: Dr. Roxane Tussiwand Hybrid Conference
Imaging DNA repair complexes in action

The Mre11-Rad50 nuclease complex has important functions to initiate the repair of broken DNA. A collaborative study of the Cejka (IRB Bellinzona) and Peter laboratories (ETH Zurich) took a new approach to image the DNA repair proteins in action. The researchers used a technique termed transmission electron microscopy, which allowed to visualize broken DNA, and […]
Countess Heidi Goëss-Horten
The Foundation for the Institute for Research in Biomedicine (IRB), and the entire IRB community, bid farewell to Countess Heidi Goëss-Horten, who passed away on June 12, 2022, and express their deep gratitude for her important contribution to the birth and development of the Institute, including for the realization of the new headquarters in Bellinzona. […]
Andrea Casagranda won the Maria Begnudelli Award at the 33rd Pezcoller Symposium
June 14, 2022: In the Symposia, an uninterrupted series of annual meetings focused on hot topics of cancer science, young investigators are encouraged to present their data in the poster session and the three best posters are awarded with the Pezcoller – Begnudelli Award and invited for oral presentation. The 2022 Maria Begnudelli Prize has been […]
One for all? A class of antibodies that targets all coronaviruses

Recently published in Science, a study led by the Sallusto Laboratory (ETH Zurich and IRB-USI, Bellinzona) and the Veesler Laboratory (University of Washington, Seattle) describes a new class of antibodies that bind to and neutralize most human and animal coronaviruses, including all SARS-CoV-2 variants. These antibodies reveal a new target for the design of universal […]
Human memory B cells are highly stable while plasmablasts are recurrent: result of a multi-year study

It is known that memory B cells persist throughout life and rapidly differentiate into antibody-producing plasma cells upon antigen encounter. However, the clonal structure of memory B cells and their relationship to newly generated plasma cells are far from being understood. By isolating circulating memory B cells and recently generated plasmablasts from two healthy adults […]