Spatial Temporal Regulation of Adaptive Immunity
IRB Special Seminar Dr. Tal Arnon Associate Professor, Kennedy Institute of Rheumatology, University of Oxford (UK) Monday, February 6, 2023 at 4:30 – 6 pm Bios+ Seminar Room Contact: Prof. Davide Robbiani
Antibodies against coronaviruses coldspots discovered
Can one single antibody catch them all? Scientists discover antibodies that recognise all SARS-CoV-2 variants and also other coronaviruses that cause human disease. The finding opens the door to the development of novel countermeasures against present and future coronavirus threats. Bellinzona, January 27, 2023 – The coronavirus keeps evolving, and in so doing it evades […]
Pfizer Research Award, IRB and IOR researchers among winners
The Pfizer Prize Foundation selected 11 studies and 21 researchers, including Dr. Fernando P. Canale, Dr. Camilla Basso and Professor Roger Geiger of the Institute for Research in Biomedicine (IRB) and Dr. Nicolò Pernigoni, Dr. Elena Zagato and Professor Arianna Calcinotto of the Institute of Oncology Research (IOR). Zurich, January 28, 2023 – The 32nd […]
Exploring the immunological effector mechanisms against intracellular pathogens and cancer
IRB Special Seminar Dr. Caroline Junqueira Associate Professor, Fiocruz Minas-Brazil (BR) and Senior Staff Scientist, Boston Children’s Hospital/Harvard Medical School (US) Monday, January 30, 2023 at 10:00 am Bios+ Seminar Room Contact: Prof. Davide Robbiani
Action of mismatch repair and WRN proteins on cruciform DNA
Cancers arise due to a broad spectrum of mutations and hence have very different genetic makeups. Efforts to develop more targeted or personalized therapies rely on potential vulnerabilities of cancer cells. In this context, it was demonstrated that cancers exhibiting microsatellite instability (MSI), are sensitive to the inhibition of the WRN helicase. These cancers include […]
IRB community pays tribute to one of its founding members: Prof. Marcus Thelen
On Nov. 30, 2022 in the building of the Bellinzona Institutes of Science (Bios+), the IRB community paid tribute to Prof. Marcus Thelen, who after 22 years at the Institute for Research in Biomedicine (IRB) went to the benefit of retirement. Prof. Thelen, an internationally recognized biochemist, was one of the founding members back in […]
Clonal composition and persistence of antigen-specific T follicular helper cells
The Sallusto group (ETH IMBB and IRB Bellinzona) published a paper in the European Journal of Immunology providing insights on the relationship of human T follicular helper cells in blood (cTfh cells) with other circulating T helper subsets and on the heterogeneity and persistence of antigen-specific cTfh cells. Follicular helper T cells (Tfh) play a […]
DNA protection: new IRB Study
The BRCA2 gene is mutated in many familial and sporadic breast and ovarian cancers, making it an important cancer suppressor. BRCA2 has been long known to function together with RAD51 in DNA break repair by homologous recombination, but more recent evidence additionally implicated BRCA2-RAD51 in the protection of newly replicated DNA against unscheduled degradation. The […]
Doctor Honoris Causa title conferred on Prof. Federica Sallusto
Bellinzona, Nov. 17, 2022 – During the Dies Academicus, the University of Fribourg conferred to Prof. Federica Sallusto the title Doctor honoris causa (Dr. h. c.) for her excellence in scientific and professional work. The University of Fribourg has awarded Federica Sallusto, group leader at the Institute for Research in Biomedicine (IRB) and professor at […]
Vitamin A delivery to the intestinal immune system
Prof. Lora Hooper Professor of Immunology, University of Texas Southwestern Medical Center (US) Date: 06.12.2022 1:00 pm Online Conference Join Zoom Meeting https://eu01web.zoom.us/j/69915307559?pwd=blZGdThqVHcySWJ1blVPNXp4QlM1dz09 Meeting ID: 699 1530 7559 Passcode: 282480 Contact: Prof. Fabio Grassi
