Nobs Samuel Philip, PhD

Publications

• Microbiome modulation of antigen presentation in tolerance and inflammation
  He, Y. Mohapatra, G. Asokan, S. Nobs, S. P. Elinav, E.
  in Curr Opin Immunol (2024) Vol.91 pp102471
  
• Complement(ing) the microbiome in infants through breastmilk
  Nobs, S. P. Elinav, E.
  in Cell Res (2024) Vol.34 pp469-470
  
• A microbial iron fist to fight tumors
  Nobs, S. P. Elinav, E.
  in Nat Immunol (2024) Vol.25 pp720-721
  
• Lung dendritic-cell metabolism underlies susceptibility to viral infection in diabetes
  Nobs, S. P. Kolodziejczyk, A. A. Adler, L. Horesh, N. Botscharnikow, C. Herzog, E. Mohapatra, G. Hejndorf, S. Hodgetts, R. J. Spivak, I. Schorr, L. Fluhr, L. Kviatcovsky, D. Zacharia, A. Njuki, S. Barasch, D. Stettner, N. Dori-Bachash, M. Harmelin, A. Brandis, A. Mehlman, T. Erez, A. He, Y. Ferrini, S. Puschhof, J. Shapiro, H. Kopf, M. Moussaieff, A. Abdeen, S. K. Elinav, E.
  in Nature (2023) Vol.624 pp645-652
  
• Nonnutritive sweeteners and glucose intolerance: Where do we go from here?
  Nobs, S. P. Elinav, E.
  in J Clin Invest (2023) Vol.133 pp
  
• Targeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation
  Federici, S. Kredo-Russo, S. Valdes-Mas, R. Kviatcovsky, D. Weinstock, E. Matiuhin, Y. Silberberg, Y. Atarashi, K. Furuichi, M. Oka, A. Liu, B. Fibelman, M. Weiner, I. N. Khabra, E. Cullin, N. Ben-Yishai, N. Inbar, D. Ben-David, H. Nicenboim, J. Kowalsman, N. Lieb, W. Kario, E. Cohen, T. Geffen, Y. F. Zelcbuch, L. Cohen, A. Rappo, U. Gahali-Sass, I. Golembo, M. Lev, V. Dori-Bachash, M. Shapiro, H. Moresi, C. Cuevas-Sierra, A. Mohapatra, G. Kern, L. Zheng, D. Nobs, S. P. Suez, J. Stettner, N. Harmelin, A. Zak, N. Puttagunta, S. Bassan, M. Honda, K. Sokol, H. Bang, C. Franke, A. Schramm, C. Maharshak, N. Sartor, R. B. Sorek, R. Elinav, E.
  in Cell (2022) Vol.185 pp2879-2898 e24
  
• Tissue-resident macrophages: guardians of organ homeostasis
  Nobs, S. P. Kopf, M.
  in Trends Immunol (2021) Vol.42 pp495-507
  
• Remembering past infections: training exercise for gut microbes
  Nobs, S. P. Elinav, E.
  in Cell Res (2021) Vol.31 pp375-376
  
• GM-CSF instigates a dendritic cell-T-cell inflammatory circuit that drives chronic asthma development
  Nobs, S. P. Pohlmeier, L. Li, F. Kayhan, M. Becher, B. Kopf, M.
  in J Allergy Clin Immunol (2021) Vol.147 pp2118-2133 e3
  
• Phages and their potential to modulate the microbiome and immunity
  Federici, S. Nobs, S. P. Elinav, E.
  in Cell Mol Immunol (2020) Vol.18 pp889-904
  
• Diet Diurnally Regulates Small Intestinal Microbiome-Epithelial-Immune Homeostasis and Enteritis
  Tuganbaev, T. Mor, U. Bashiardes, S. Liwinski, T. Nobs, S. P. Leshem, A. Dori-Bachash, M. Thaiss, C. A. Pinker, E. Y. Ratiner, K. Adlung, L. Federici, S. Kleimeyer, C. Moresi, C. Yamada, T. Cohen, Y. Zhang, X. Massalha, H. Massasa, E. Kuperman, Y. Koni, P. A. Harmelin, A. Gao, N. Itzkovitz, S. Honda, K. Shapiro, H. Elinav, E.
  in Cell (2020) Vol.182 pp1441-1459 e21
  
• Nutrition Regulates Innate Immunity in Health and Disease
  Nobs, S. P. Zmora, N. Elinav, E.
  in Annu Rev Nutr (2020) Vol.40 pp189-219
  
• Walk on the wildling side
  Nobs, S. P. Elinav, E.
  in Science (2019) Vol.365 pp444-445
  
• Microbiome diurnal rhythmicity and its impact on host physiology and disease risk
  Nobs, S. P. Tuganbaev, T. Elinav, E.
  in EMBO Rep (2019) Vol.20 pp
  
• GM-CSF intrinsically controls eosinophil accumulation in the setting of allergic airway inflammation
  Nobs, S. P. Kayhan, M. Kopf, M.
  in J Allergy Clin Immunol (2018) Vol.143 pp1513-1524 e2
  
• PPAR-gamma in innate and adaptive lung immunity
  Nobs, S. P. Kopf, M.
  in J Leukoc Biol (2018) Vol.104 pp737-741
  
• NFIL-trating the Host Circadian Rhythm-Microbes Fine-Tune the Epithelial Clock
  Thaiss, C. A. Nobs, S. P. Elinav, E.
  in Cell Metab (2017) Vol.26 pp699-700
  
• PPARgamma in dendritic cells and T cells drives pathogenic type-2 effector responses in lung inflammation
  Nobs, S. P. Natali, S. Pohlmeier, L. Schneider, C. Kurrer, M. Sallusto, F. Kopf, M.
  in J Exp Med (2017) Vol.214 pp3015-3035
  
• Frontline Science: Coincidental null mutation of Csf2ralpha in a colony of PI3Kgamma-/- mice causes alveolar macrophage deficiency and fatal respiratory viral infection
  Schneider, C. Nobs, S. P. Heer, A. K. Hirsch, E. Penninger, J. Siggs, O. M. Kopf, M.
  in J Leukoc Biol (2016) Vol.101 pp367-376
  
• PI3Kgamma Is Critical for Dendritic Cell-Mediated CD8+ T Cell Priming and Viral Clearance during Influenza Virus Infection
  Nobs, S. P. Schneider, C. Heer, A. K. Huotari, J. Helenius, A. Kopf, M.
  in PLoS Pathog (2016) Vol.12 ppe1005508
  
• PI3-Kinase-gamma Has a Distinct and Essential Role in Lung-Specific Dendritic Cell Development
  Nobs, S. P. Schneider, C. Dietrich, M. G. Brocker, T. Rolink, A. Hirsch, E. Kopf, M.
  in Immunity (2015) Vol.43 pp674-89
  
• The development and function of lung-resident macrophages and dendritic cells
  Kopf, M. Schneider, C. Nobs, S. P.
  in Nat Immunol (2015) Vol.16 pp36-44
  
• Influenza A virus uses the aggresome processing machinery for host cell entry
  Banerjee, I. Miyake, Y. Nobs, S. P. Schneider, C. Horvath, P. Kopf, M. Matthias, P. Helenius, A. Yamauchi, Y.
  in Science (2014) Vol.346 pp473-7
  
• Induction of the nuclear receptor PPAR-gamma by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages
  Schneider, C. Nobs, S. P. Kurrer, M. Rehrauer, H. Thiele, C. Kopf, M.
  in Nat Immunol (2014) Vol.15 pp1026-37
  
• Alveolar macrophages are essential for protection from respiratory failure and associated morbidity following influenza virus infection
  Schneider, C. Nobs, S. P. Heer, A. K. Kurrer, M. Klinke, G. van Rooijen, N. Vogel, J. Kopf, M.
  in PLoS Pathog (2014) Vol.10 ppe1004053
  
• What Makes the Lung Unique – Tissue-Specific Immunity in the Respiratory Tract
  Nobs, S. P.
  in European Medical Journal Respiratory (1970) Vol.5 pp80-90.