Junqueira Caroline, PhD

Publications

• Leishmania (Sauroleishmania) tarentolae versus pathogenic species: comparative evaluation of protease activity, glycoconjugates, resistance to complement and metabolome composition
  Andrade, F. F. D. Vitorio, J. G. Canuto, G. A. B. Nunes, F. F. C. Rodrigues, I. A. Almeida, Apmm Nascimento, F. C. Costa, A. O. Vieira, T. D. S. Silva, A. C. C. Andre, L. C. Gontijo, C. M. F. Junqueira, C. Toledo, J. S. Fernandes, A. P. Soares, R. P.
  in Mem Inst Oswaldo Cruz (2024) Vol.119 ppe230243
  
• Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis
  Miao, R. Jiang, C. Chang, W. Y. Zhang, H. An, J. Ho, F. Chen, P. Junqueira, C. Amgalan, D. Liang, F. G. Zhang, J. Evavold, C. L. Hafner-Bratkovic, I. Zhang, Z. Fontana, P. Xia, S. Waldeck-Weiermair, M. Pan, Y. Michel, T. Bar-Peled, L. Wu, H. Kagan, J. C. Kitsis, R. N. Zhang, P. Liu, X. Lieberman, J.
  in Immunity (2023) Vol. pp
  
• Relationship between clinical-epidemiological parameters and outcomes of patients with COVID-19 admitted to the intensive care unit: a report from a Brazilian hospital
  D'Carmo Sodre, M. M. Dos Santos, U. R. Povoas, H. P. Guzman, J. L. Junqueira, C. Trindade, T. O. Gadelha, S. R. Romano, C. C. da Conceicao, A. O. Gross, E. Silva, A. Rezende, R. P. Fontana, R. da Mata, Cpsm Marin, L. J. de Carvalho, L. D.
  in Front Public Health (2023) Vol.11 pp1241444
  
• ASP-2/Trans-sialidase chimeric protein induces robust protective immunity in experimental models of Chagas’ disease
  Castro, J. T. Brito, R. Hojo-Souza, N. S. Azevedo, B. Salazar, N. Ferreira, C. P. Junqueira, C. Fernandes, A. P. Vasconcellos, R. Cardoso, J. M. Aguiar-Soares, R. D. O. Vieira, P. M. A. Carneiro, C. M. Valiate, B. Toledo, C. Salazar, A. M. Caballero, O. Lannes-Vieira, J. Teixeira, S. R. Reis, A. B. Gazzinelli, R. T.
  in NPJ Vaccines (2023) Vol.8 pp81
  
• Accumulation of Neutrophil Phagocytic Antibody Features Tracks With Naturally Acquired Immunity Against Malaria in Children
  Nziza, N. Tran, T. M. DeRiso, E. A. Dolatshahi, S. Herman, J. D. de Lacerda, L. Junqueira, C. Lieberman, J. Ongoiba, A. Doumbo, S. Kayentao, K. Traore, B. Crompton, P. D. Alter, G.
  in J Infect Dis (2023) Vol. pp
  
• The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells
  Sen Santara, S. Lee, D. J. Crespo, A. Hu, J. J. Walker, C. Ma, X. Zhang, Y. Chowdhury, S. Meza-Sosa, K. F. Lewandrowski, M. Zhang, H. Rowe, M. McClelland, A. Wu, H. Junqueira, C. Lieberman, J.
  in Nature (2023) Vol.616 pp348-356
  
• In Vitro Assay of Plasmodium-Infected Red Blood Cell Killing by Cytotoxic Lymphocytes
  de Lacerda, L. Castro, G. Gomes, C. Junqueira, C.
  in J Vis Exp (2022) Vol. pp
  
• Inflammasome activation in infected macrophages drives COVID-19 pathology
  Sefik, E. Qu, R. Junqueira, C. Kaffe, E. Mirza, H. Zhao, J. Brewer, J. R. Han, A. Steach, H. R. Israelow, B. Blackburn, H. N. Velazquez, S. E. Chen, Y. G. Halene, S. Iwasaki, A. Meffre, E. Nussenzweig, M. Lieberman, J. Wilen, C. B. Kluger, Y. Flavell, R. A.
  in Nature (2022) Vol.606 pp585-593
  
• FcgammaR-mediated SARS-CoV-2 infection of monocytes activates inflammation
  Junqueira, C. Crespo, A. Ranjbar, S. de Lacerda, L. B. Lewandrowski, M. Ingber, J. Parry, B. Ravid, S. Clark, S. Schrimpf, M. R. Ho, F. Beakes, C. Margolin, J. Russell, N. Kays, K. Boucau, J. Das Adhikari, U. Vora, S. M. Leger, V. Gehrke, L. Henderson, L. A. Janssen, E. Kwon, D. Sander, C. Abraham, J. Goldberg, M. B. Wu, H. Mehta, G. Bell, S. Goldfeld, A. E. Filbin, M. R. Lieberman, J.
  in Nature (2022) Vol.606 pp576-584
  
• Improved Performance of ELISA and Immunochromatographic Tests Using a New Chimeric A2-Based Protein for Human Visceral Leishmaniasis Diagnosis
  Figueiredo, M. M. Dos Santos, A. R. R. Godoi, L. C. de Castro, N. S. de Andrade, B. C. Sergio, S. A. R. Jeronimo, S. M. B. de Oliveira, E. J. Valencia-Portillo, R. T. Bezerra, L. M. Goto, H. Sanchez, M. C. A. Junqueira, C. Teixeira, S. M. R. da Fonseca, F. G. Gazzinelli, R. T. Fernandes, A. P.
  in J Immunol Res (2021) Vol.2021 pp5568077
  
• Immunotherapy for breast cancer using EpCAM aptamer tumor-targeted gene knockdown
  Zhang, Y. Xie, X. Yeganeh, P. N. Lee, D. J. Valle-Garcia, D. Meza-Sosa, K. F. Junqueira, C. Su, J. Luo, H. R. Hide, W. Lieberman, J.
  in Proc Natl Acad Sci U S A (2021) Vol.118 pp:e2022830118
  
• gammadelta T cells suppress Plasmodium falciparum blood-stage infection by direct killing and phagocytosis
  Junqueira, C. Polidoro, R. B. Castro, G. Absalon, S. Liang, Z. Sen Santara, S. Crespo, A. Pereira, D. B. Gazzinelli, R. T. Dvorin, J. D. Lieberman, J.
  in Nat Immunol (2021) Vol.22 pp347-357
  
• Caspase-8 mediates inflammation and disease in rodent malaria
  Pereira, L. M. N. Assis, P. A. de Araujo, N. M. Durso, D. F. Junqueira, C. Ataide, M. A. Pereira, D. B. Lien, E. Fitzgerald, K. A. Zamboni, D. S. Golenbock, D. T. Gazzinelli, R. T.
  in Nat Commun (2020) Vol.11 pp4596
  
• Contributions of IFN-gamma and granulysin to the clearance of Plasmodium yoelii blood stage
  Hojo-Souza, N. S. de Azevedo, P. O. de Castro, J. T. Teixeira-Carvalho, A. Lieberman, J. Junqueira, C. Gazzinelli, R. T.
  in PLoS Pathog (2020) Vol.16 ppe1008840
  
• Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts
  Crespo, A. C. Mulik, S. Dotiwala, F. Ansara, J. A. Sen Santara, S. Ingersoll, K. Ovies, C. Junqueira, C. Tilburgs, T. Strominger, J. L. Lieberman, J.
  in Cell (2020) Vol.182 pp1125-1139 e18
  
• Gasdermin E suppresses tumour growth by activating anti-tumour immunity
  Zhang, Z. Zhang, Y. Xia, S. Kong, Q. Li, S. Liu, X. Junqueira, C. Meza-Sosa, K. F. Mok, T. M. Y. Ansara, J. Sengupta, S. Yao, Y. Wu, H. Lieberman, J.
  in Nature (2020) Vol.579 pp415-420
  
• The immunology of Plasmodium vivax malaria
  Antonelli, L. R. Junqueira, C. Vinetz, J. M. Golenbock, D. T. Ferreira, M. U. Gazzinelli, R. T.
  in Immunol Rev (2019) Vol.293 pp163-189
  
• Cytotoxic CD8(+) T cells recognize and kill Plasmodium vivax-infected reticulocytes
  Junqueira, C. Barbosa, C. R. R. Costa, P. A. C. Teixeira-Carvalho, A. Castro, G. Sen Santara, S. Barbosa, R. P. Dotiwala, F. Pereira, D. B. Antonelli, L. R. Lieberman, J. Gazzinelli, R. T.
  in Nat Med (2018) Vol.24 pp1330-1336
  
• New Vaccine Formulations Containing a Modified Version of the Amastigote 2 Antigen and the Non-Virulent Trypanosoma cruzi CL-14 Strain Are Highly Antigenic and Protective against Leishmania infantum Challenge
  Almeida, Apmm Machado, L. F. M. Doro, D. Nascimento, F. C. Damasceno, L. Gazzinelli, R. T. Fernandes, A. P. Junqueira, C.
  in Front Immunol (2018) Vol.9 pp465
  
• Comparative transcriptome profiling of virulent and non-virulent Trypanosoma cruzi underlines the role of surface proteins during infection
  Belew, A. T. Junqueira, C. Rodrigues-Luiz, G. F. Valente, B. M. Oliveira, A. E. R. Polidoro, R. B. Zuccherato, L. W. Bartholomeu, D. C. Schenkman, S. Gazzinelli, R. T. Burleigh, B. A. El-Sayed, N. M. Teixeira, S. M. R.
  in PLoS Pathog (2017) Vol.13 ppe1006767
  
• Down Modulation of Host Immune Response by Amino Acid Repeats Present in a Trypanosoma cruzi Ribosomal Antigen
  Toro Acevedo, C. A. Valente, B. M. Burle-Caldas, G. A. Galvao-Filho, B. Santiago, H. D. C. Esteves Arantes, R. M. Junqueira, C. Gazzinelli, R. T. Roffe, E. Teixeira, S. M. R.
  in Front Microbiol (2017) Vol.8 pp2188
  
• Virus-like Particle Display of the alpha-Gal Carbohydrate for Vaccination against Leishmania Infection
  Moura, A. P. V. Santos, L. C. B. Brito, C. R. N. Valencia, E. Junqueira, C. Filho, A. A. P. Sant'Anna, M. R. V. Gontijo, N. F. Bartholomeu, D. C. Fujiwara, R. T. Gazzinelli, R. T. McKay, C. S. Sanhueza, C. A. Finn, M. G. Marques, A. F.
  in ACS Cent Sci (2017) Vol.3 pp1026-1031
  
• Introdução à técnica de CRISPR (Introduction to CRISPR methodology)
  Pereira, TC. , Junqueira, C.,
  in (2016) Vol. pp
  
• Type I Interferon Transcriptional Signature in Neutrophils and Low-Density Granulocytes Are Associated with Tissue Damage in Malaria
  Rocha, B. C. Marques, P. E. Leoratti, F. M. S. Junqueira, C. Pereira, D. B. Antonelli, Lrdv Menezes, G. B. Golenbock, D. T. Gazzinelli, R. T.
  in Cell Rep (2015) Vol.13 pp2829-2841
  
• Induction of Inhibitory Receptors on T Cells During Plasmodium vivax Malaria Impairs Cytokine Production
  Costa, P. A. Leoratti, F. M. Figueiredo, M. M. Tada, M. S. Pereira, D. B. Junqueira, C. Soares, I. S. Barber, D. L. Gazzinelli, R. T. Antonelli, L. R.
  in J Infect Dis (2015) Vol.212 pp1999-2010
  
• Blockade of CTLA-4 promotes the development of effector CD8+ T lymphocytes and the therapeutic effect of vaccination with an attenuated protozoan expressing NY-ESO-1
  Dos Santos, L. I. Galvao-Filho, B. de Faria, P. C. Junqueira, C. Dutra, M. S. Teixeira, S. M. Rodrigues, M. M. Ritter, G. Bannard, O. Fearon, D. T. Antonelli, L. R. Gazzinelli, R. T.
  in Cancer Immunol Immunother (2014) Vol.64 pp311-23
  
• Identification and functional analysis of Trypanosoma cruzi genes that encode proteins of the glycosylphosphatidylinositol biosynthetic pathway
  Cardoso, M. S. Junqueira, C. Trigueiro, R. C. Shams-Eldin, H. Macedo, C. S. Araujo, P. R. Gomes, D. A. Martinelli, P. M. Kimmel, J. Stahl, P. Niehus, S. Schwarz, R. T. Previato, J. O. Mendonca-Previato, L. Gazzinelli, R. T. Teixeira, S. M.
  in PLoS Negl Trop Dis (2013) Vol.7 ppe2369
  
• Trypanosoma cruzi adjuvants potentiate T cell-mediated immunity induced by a NY-ESO-1 based antitumor vaccine
  Junqueira, C. Guerrero, A. T. Galvao-Filho, B. Andrade, W. A. Salgado, A. P. Cunha, T. M. Ropert, C. Campos, M. A. Penido, M. L. Mendonca-Previato, L. Previato, J. O. Ritter, G. Cunha, F. Q. Gazzinelli, R. T.
  in PLoS One (2012) Vol.7 ppe36245
  
• Trypanosoma cruzi as an effective cancer antigen delivery vector
  Junqueira, C. Santos, L. I. Galvao-Filho, B. Teixeira, S. M. Rodrigues, F. G. DaRocha, W. D. Chiari, E. Jungbluth, A. A. Ritter, G. Gnjatic, S. Old, L. J. Gazzinelli, R. T.
  in Proc Natl Acad Sci U S A (2011) Vol.108 pp19695-700
  
• The endless race between Trypanosoma cruzi and host immunity: lessons for and beyond Chagas disease
  Junqueira, C. Caetano, B. Bartholomeu, D. C. Melo, M. B. Ropert, C. Rodrigues, M. M. Gazzinelli, R. T.
  in Expert Rev Mol Med (2010) Vol.12 ppe29
  
• Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi
  Bartholomeu, D. C. Ropert, C. Melo, M. B. Parroche, P. Junqueira, C. F. Teixeira, S. M. Sirois, C. Kasperkovitz, P. Knetter, C. F. Lien, E. Latz, E. Golenbock, D. T. Gazzinelli, R. T.
  in J Immunol (2008) Vol.181 pp1333-44
  
• Purification, crystallization and preliminary X-ray analysis of CMS1MS2: a cysteine proteinase from Carica candamarcensis latex
  Gomes, M. T. Teixeira, R. D. Ribeiro Hde, A. Turchetti, A. P. Junqueira, C. F. Lopes, M. T. Salas, C. E. Nagem, R. A.
  in Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) Vol.64 pp492-4