González F. Santiago, PhD, PhD

Publications

• Stealth mRNA nanovaccines to control lymph node trafficking
  Garcia-Fernandez, C. Virgilio, T. Latino, I. Guerra-Rebollo, M. Gonzalez, S. F. Borros, S. Fornaguera, C.
  in J Control Release (2024) Vol.374 pp325-336
  
• Plitidepsin as an Immunomodulator against Respiratory Viral Infections
  Losada, A. Izquierdo-Useros, N. Aviles, P. Vergara-Alert, J. Latino, I. Segalés, J. Gonzalez, S. Cuevas, C. Raïch-Regué, D. Muñoz-Alonso, M. J. Perez-Zsolt, D. Muñoz-Basagoiti, J. Rodon, J. Chang, L. A. Warang, P. Singh, G. Brustolin, M. Cantero, G.; Roca, N. Pérez, M. Eugenio Bustos-Morán; White, K. Schotsaert, M. García-Sastre, A.
  in J Immunol. (2024) Vol. pp
  
• Transformer-based spatial-temporal detection of apoptotic cell death in live-cell imaging
  Pulfer, A. Pizzagalli, D. U. Gagliardi, P. A. Hinderling, L. Lopez, P. Zayats, R. Carrillo-Barberà, P. Antonello, P. Palomino-Segura, M. Giusti, A. Thelen, M. Gambardella, L. M. Murooka, T. T. Pertz, O. Krause, R. Gonzalez, S.
  in eLife (2023) Vol.12 ppRP90502
  
• Subcapsular sinus macrophages promote melanoma metastasis to the sentinel lymph nodes via an IL-1alpha-STAT3 axis
  Virgilio, T. Bordini, J. Cascione, L. Sartori, G. Latino, I. Molina Romero, D. Leoni, C. Akhmedov, M. Rinaldi, A. Arribas, A. J. Morone, D. Seyed Jafari, S. M. Bersudsky, M. Ottolenghi, A. Kwee, I. Chiaravalli, A. M. Sessa, F. Hunger, R. E. Bruno, A. Mortara, L. Voronov, E. Monticelli, S. Apte, R. N. Bertoni, F. Gonzalez, S. F.
  in Cancer Immunol Res (2022) Vol.10 pp1525-1541
  
• CANCOL, a Computer-Assisted Annotation Tool to Facilitate Colocalization and Tracking of Immune Cells in Intravital Microscopy
  Pizzagalli, D. U. Bordini, J. Morone, D. Pulfer, A. Carrillo-Barbera, P. Thelen, B. Ceni, K. Thelen, M. Krause, R. Gonzalez, S. F.
  in J Immunol (2022) Vol. pp
  
• In Vivo Motility Patterns Displayed by Immune Cells Under Inflammatory Conditions
  Pizzagalli, D. U. Pulfer, A. Thelen, M. Krause, R. Gonzalez, S. F.
  in Front Immunol (2022) Vol.12 pp804159
  
• Behavioural immune landscapes of inflammation
  Crainiciuc, G. Palomino-Segura, M. Molina-Moreno, M. Sicilia, J. Aragones, D. G. Li, J. L. Y. Madurga, R. Adrover, J. M. Aroca-Crevillen, A. Martin-Salamanca, S. Del Valle, A. S. Castillo, S. D. Welch, H. C. E. Soehnlein, O. Graupera, M. Sanchez-Cabo, F. Zarbock, A. Smithgall, T. E. Di Pilato, M. Mempel, T. R. Tharaux, P. L. Gonzalez, S. F. Ayuso-Sacido, A. Ng, L. G. Calvo, G. F. Gonzalez-Diaz, I. Diaz-de-Maria, F. Hidalgo, A.
  in Nature (2022) Vol. pp
  
• Neutrophil subtypes shape HIV-specific CD8 T-cell responses after vaccinia virus infection
  Di Pilato, M. Palomino-Segura, M. Mejias-Perez, E. Gomez, C. E. Rubio-Ponce, A. D'Antuono, R. Pizzagalli, D. U. Perez, P. Kfuri-Rubens, R. Benguria, A. Dopazo, A. Ballesteros, I. Sorzano, C. O. S. Hidalgo, A. Esteban, M. Gonzalez, S. F.
  in NPJ Vaccines (2021) Vol.6 pp52
  
• Carboxymethyl-beta-glucan/chitosan nanoparticles: new thermostable and efficient carriers for antigen delivery
  Cordeiro, A. S. Farsakoglu, Y. Crecente-Campo, J. de la Fuente, M. Gonzalez, S. F. Alonso, M. J.
  in Drug Deliv Transl Res (2021) Vol. pp
  
• Spatio-temporal profile of innate inflammatory cells and mediators during influenza virus infection
  Latino, I. Gonzalez F., S.
  in Curr Opin Physiol (2020) Vol.19 pp175-186
  
• Targeting a scavenger receptor on tumor-associated macrophages activates tumor cell killing by natural killer cells
  Eisinger, S. Sarhan, D. Boura, V. F. Ibarlucea-Benitez, I. Tyystjarvi, S. Oliynyk, G. Arsenian-Henriksson, M. Lane, D. Wikstrom, S. L. Kiessling, R. Virgilio, T. Gonzalez, S. F. Kaczynska, D. Kanatani, S. Daskalaki, E. Wheelock, C. E. Sedimbi, S. Chambers, B. J. Ravetch, J. V. Karlsson, M. C. I.
  in Proc Natl Acad Sci U S A (2020) Vol.117 pp32005-32016
  
• Early production of IL-17A by gammadelta T cells in the trachea promotes viral clearance during influenza infection in mice
  Palomino-Segura, M. Latino, I. Farsakoglu, Y. Gonzalez, S. F.
  in Eur J Immunol (2019) Vol.50 pp97-109
  
• Characterization of the Dynamic Behavior of Neutrophils Following Influenza Vaccination
  Pizzagalli, D. U., Latino, I., Pulfer, A. , Virgilio, T., Farsakoglu, Y. , Krause, R., Gonzalez, S. F.
  in Frontiers in Immunology (2019) Vol.10 pp2621
  
• Design of polymeric nanocapsules to improve their lympho-targeting capacity
  Crecente-Campo, J. Virgilio, T. Morone, D. Fernandez-Marino, I. Olivera, A. Varela-Calvino, R. Gonzalez, S. F. Alonso, M. J.
  in Nanomedicine (Lond) (2019) Vol.14 pp3013-3033
  
• A trainable clustering algorithm based on shortest paths from density peaks
  Pizzagalli, D. U. Gonzalez, S. F. Krause, R.
  in Science Advances (2019) Vol.5 ppeaax3770
  
• Protection against influenza infection requires early recognition by inflammatory dendritic cells through C-type lectin receptor SIGN-R1
  Palomino-Segura, M. Perez, L. Farsakoglu, Y. Latino, I. D'Antuono, R. Chatziandreou, N. Pizzagalli, D. U. Wang, G. Garcia-Sastre, A. Sallusto, F. Carroll, M. C. Neyrolles, O. Gonzalez, S. F.
  in Nat Microbiol (2019) Vol.4 pp1930-1940
  
• Influenza Vaccination Induces NK-Cell-Mediated Type-II IFN Response that Regulates Humoral Immunity in an IL-6-Dependent Manner
  Farsakoglu, Y. Palomino-Segura, M. Latino, I. Chatziandreou, N. Pizzagalli, D. U. Rinaldi, A. Bolis, M. Sallusto, F. Stein, J. V. Gonzalez, S. F.
  in Cell Rep (2019) Vol.26 pp2307-2315
  
• Two-Photon Intravital Imaging of Leukocytes in the Trachea During Pneumococcal Infection
  Palomino-Segura, M. Gonzalez, S. F.
  in Methods Mol Biol (2019) Vol.1968 pp183-194
  
• ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens
  Proietti, M. Perruzza, L. Scribano, D. D'Antuono, R. Strati, F. Raffaelli, M. Gonzalez, S. F. Thelen, M. Hardt, W. D. Slack, E. Nicoletti, M. Grassi, F.
  in Nat Commun (2019) Vol.10 pp250
  
• Engineering polymeric nanocapsules for an efficient drainage and biodistribution in the lymphatic system
  Cordeiro, A. S. Crecente-Campo, J. Lopez-Bouzo, B. Gonzalez, S. F. de la Fuente, M. Alonso, M. J.
  in J Drug Target (2019) Vol. pp1-52
  
• A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity
  Bardelli, M. Frontzek, K. Simonelli, L. Pedotti, M. Mazzola, F. Carta, M. Eckhardt, V. D'Antuono, R. Virgilio, T. Gonzalez, S. F. Aguzzi, A. Varani, L.
  in PLoS Pathog (2018) Vol.14 ppe1007335
  
• Imaging Cell Interaction in Tracheal Mucosa During Influenza Virus Infection Using Two-photon Intravital Microscopy
  Palomino-Segura, M. Virgilio, T. Morone, D. Gonzalez, S.
  in JoVE (2018) Vol. ppe58355
  
• Leukocyte Tracking Database, a collection of immune cell tracks from intravital 2-photon microscopy videos
  Pizzagalli, D. U. Farsakoglu, Y. Palomino-Segura, M. Sintes, J. Marangoni, F. Mempel, T. R. Koh, W. H. Murooka, T. T. Thelen, F. Stein, J. V. Pozzi, G. Thelen, M. Krause, R. Gonzalez, S. F.
  in Sci Data (2018) Vol.5 pp180129
  
• Epithelial-Mesenchymal transition in cancer metastasis through the lymphatic system
  Karlsson, M. C. Gonzalez, S. F. Welin, J.
  in Mol Oncol (2017) Vol.11 pp781-791
  
• Macrophage Death following Influenza Vaccination Initiates the Inflammatory Response that Promotes Dendritic Cell Function in the Draining Lymph Node
  Chatziandreou, N. Farsakoglu, Y. Palomino-Segura, M. Pizzagalli, D. U. Sallusto, F. Lukacs-Kornek, V. Uguccioni, M. Corti, D. Turley, S. J. Lanzavecchia, A. Carroll, M. C. Gonzalez, S. F.
  in Cell Rep (2017) Vol.18 pp2427-2440
  
• Dynamic intravital imaging of cell-cell interactions in the lymph node
  Stein, J. V. Gonzalez, S. F.
  in J Allergy Clin Immunol (2017) Vol.139 pp12-20
  
• Development of a SYBR green I real-time PCR assay for specific identification of the fish pathogen Aeromonas salmonicida subspecies salmonicida
  Fernandez-Alvarez, C. Gonzalez, S. F. Santos, Y.
  in Appl Microbiol Biotechnol (2016) Vol.100 pp10585-10595
  
• Antibody-Mediated Immunity
  Baumgarth, N. Carroll, M. C. Gonzalez, S. F.
  in Textbook of Influenza, 2nd Edition (2013) Vol. pp
  
• Endocytosis and recycling of immune complexes by follicular dendritic cells enhances B cell antigen binding and activation
  Heesters, B. A. Chatterjee, P. Kim, Y. A. Gonzalez, S. F. Kuligowski, M. P. Kirchhausen, T. Carroll, M. C.
  in Immunity (2013) Vol.38 pp1164-75
  
• Cochlin produced by follicular dendritic cells promotes antibacterial innate immunity
  Py, B. F. Gonzalez, S. F. Long, K. Kim, Y. A. Zhu, H. Yao, J. Degauque, N. Villet, R. Ymele-Leki, P. Gadjeva, M. Pier, G. B. Carroll, M. C. Yuan, J.
  in Immunity (2013) Vol.38 pp1063-72
  
• Podoplanin-rich stromal networks induce dendritic cell motility via activation of the C-type lectin receptor CLEC-2
  Acton, S. E. Astarita, J. L. Malhotra, D. Franz, B. Hess, P. R. Jakus, Z. Kuligowski, M. Fletcher, A. L. Elpek, K. G. Bellemare-Pelletier, A. Sceats, L. Reynoso, E. D. Gonzalez, S. F. Graham, D. B. Chang, J. Peters, A. Woodruff, M. Kim, Y. A. Swat, W. Morita, T. Kuchroo, V. Carroll, M. C. Kahn, M. L. Wucherpfennig, K. W. Turley, S. J.
  in Immunity (2012) Vol.37 pp276-89
  
• Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks
  Malhotra, D. Fletcher, A. L. Astarita, J. Tayalia, P. Gonzalez, S. F. Elpek, K. G. Chang, S. K. Knoblich, K. Hemler, M. E. Brenner, M. B. Carroll, M. C. Mooney, D. J. Turley, S. J.
  in Nat Immunol (2012) Vol.13 pp499-510
  
• Molecular cloning and expression of two beta-defensin and two mucin genes in common carp (Cyprinus carpio L.) and their up-regulation after beta-glucan feeding
  Marel, Mv Adamek, M. Gonzalez, S. F. Rombout, J. H. Wiegertjes, G. F. Savelkoul, H. F. Steinhagen, D.
  in Fish Shellfish Immunol (2012) Vol.32 pp494-501
  
• Trafficking of B cell antigen in lymph nodes
  Gonzalez, S. F. Degn, S. E. Pitcher, L. A. Heesters, B. A. Carroll, M. C.
  in Annu Rev Immunol (2011) Vol.29 pp215-33
  
• The role of innate immunity in B cell acquisition of antigen within LNs
  Gonzalez, S. F. Kuligowski, M. P. Pitcher, L. A. Carroll, M. C.
  in Adv Immunol (2010) Vol.106 pp1-19
  
• Complement-dependent transport of antigen into B cell follicles
  Gonzalez, S. F. Lukacs-Kornek, V. Kuligowski, M. P. Degn, S. E. Turley, S. J. Carroll, M. C.
  in J Immunol (2010) Vol.185 pp2659-64
  
• SIGN-R1-expressing dendritic cells are important for humoral immunity to influenza virus
  Pitcher, L. A. Gonzalez, S. F. Lukacs-Kornek, V. Kim, Y. A. Martinez-Pomares, L. Gordon, S. Turley, S. J. Carroll, M. C.
  in Mol Immunol (2010) Vol.47 pp2227-2227
  
• The role of the complement system in trafficking of a Streptococcus vaccine in the lymph node
  Heesters, B. A. Gonzalez, S. F. Carroll, M. C.
  in Mol Immunol (2010) Vol.47 pp2249-2249
  
• Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes
  Gonzalez, S. F. Lukacs-Kornek, V. Kuligowski, M. P. Degn, S. E. Kim, Y. A. Cloninger, M. J. Martinez-Pomares, L. Gordon, S. Turley, S. J. Carroll, M. C.
  in Nat Immunol (2010) Vol.11 pp427-34
  
• Serological methods for the detection of pathogenic bacteria in aquaculture: Present status and future prospects
  Gonzalez, S. F. Santos, Y.
  in Fisheries, aquaculture and biotechnology (2009) Vol. pp
  
• B cell acquisition of antigen in vivo
  Gonzalez, S. F. Pitcher, L. A. Mempel, T. Carroll, M. C.
  in Curr Opin Immunol (2009) Vol.21 pp251-7
  
• Conduits mediate transport of low-molecular-weight antigen to lymph node follicles
  Roozendaal, R. Mempel, T. R. Pitcher, L. A. Verschoor, A. Mebius, R. E. von Andrian, U. H. Carroll, M. C.
  in Immunity (2009) Vol.30 pp264-76
  
• Genomic resources and microarrays for the common carp Cyprinus carpio L.
  Williams, D. R. Li, W. Hughes, M. A. Vernon, C. Vidal, M. C. Jeney, Z. Jeney, G. Dixon, P. McAndrew, B. Bartfai, R. Orban, L. Trudeau, V. Rogers, J. Matthews, L. Fraser, E. J. Gracey, A. Y. Cossins, A. R.
  in J Fish Biology (2008) Vol.72 pp2095-2117
  
• Differential transcription of multiple forms of alpha-2-macroglobulin in carp (Cyprinus carpio) infected with parasites
  Onara, D. F. Forlenza, M. Gonzalez, S. F. Pilarczyk, A. Irnazarow, I. Wiegertjes, G. F.
  in Dev Comp Immunol (2007) Vol.32 pp339-47
  
• Complement expression in common carp (Cyprinus carpio L.) during infection with Ichthyophthirius multifiliis
  Gonzalez, S. F. Buchmann, K. Nielsen, M. E.
  in Dev Comp Immunol (2006) Vol.31 pp576-86
  
• Ichthyophthirius multifiliis infection induces massive up-regulation of serum amyloid A in carp (Cyprinus carpio)
  Gonzalez, S. F. Buchmann, K. Nielsen, M. E.
  in Vet Immunol Immunopathol (2006) Vol.115 pp172-8
  
• Cutaneous immune responses in the common carp detected using transcript analysis
  Gonzalez, S. F. Chatziandreou, N. Nielsen, M. E. Rogers, J. Taylor, R. Santos, Y. Cossins, A.
  in Mol Immunol (2006) Vol.44 pp1664-79
  
• Real-time gene expression analysis in carp (Cyprinus carpio L.) skin: inflammatory responses caused by the ectoparasite Ichthyophthirius multifiliis
  Gonzalez, S. F. Buchmann, K. Nielsen, M. E.
  in Fish Shellfish Immunol (2006) Vol.22 pp641-50
  
• Real-time gene expression analysis in carp (Cyprinus carpio L.) skin: inflammatory responses to injury mimicking infection with ectoparasites
  Gonzalez, S. F. Huising, M. O. Stakauskas, R. Lidy Verburg-van Kemenade, B. M. Buchmann, K. Nielsen, M. E. Wiegertjes, G. F.
  in Dev Comp Immunol (2006) Vol.31 pp244-54
  
• Evaluation of the AQUARAPID-Va, AQUAEIA-Va and dot-blot assays for the detection of Vibrio anguillarum in fish tissues
  Gonzalez, S. F. Osorio, C. R. Santos, Y.
  in J Fish Dis (2004) Vol.27 pp617-21
  
• Simultaneous detection of marine fish pathogens by using multiplex PCR and a DNA microarray
  Gonzalez, S. F. Krug, M. J. Nielsen, M. E. Call, D. R.
  in J Clin Microbiol (2004) Vol.42 pp1414-9
  
• Development of a PCR-based method for the detection of Listonella anguillarum in fish tissues and blood samples
  Gonzalez, S. F. Osorio, C. R. Santos, Y.
  in Dis Aquat Organ (2003) Vol.55 pp109-15