{"id":7604,"date":"2010-03-02T00:00:00","date_gmt":"2010-03-01T22:00:00","guid":{"rendered":"https:\/\/irb.usi.ch\/uncategorized\/irb-scientist-named-young-researcher-honoree\/"},"modified":"2010-03-02T00:00:00","modified_gmt":"2010-03-01T22:00:00","slug":"irb-scientist-named-young-researcher-honoree","status":"publish","type":"post","link":"https:\/\/irb.usi.ch\/it\/news\/irb-scientist-named-young-researcher-honoree\/","title":{"rendered":"IRB Scientist named “Young Researcher Honoree”"},"content":{"rendered":"

on<\/span> March 2, 2010<\/span><\/p>\n

\n\tDavide Corti, PhD
\n\tInstitute for Research in Biomedicine
\n\tNominated by Prof. Robin Weiss<\/h2>\n

\n\t\"\"<\/p>\n

\n\tDr. Davide Corti is currently Director of the Antibody Discovery Unit at Humabs LLC, a spin-out company of the Institute of Research in Biomedicine. Dr. Corti completed his Ph.D. in Antonio Lanzavecchia\u2019s laboratory in December 2007 where he studied the human memory B cell repertoire as an accessible source of all the antibody specificities produced during the lifespan of an individual. The dissection of the memory B cell repertoire was performed using two independent approaches: the first aimed to establish frequency and fine specificity of memory B cells for a variety of human pathogens and their kinetics following infection or vaccination, the second aimed to interrogate the B cell repertoire for the isolation of human monoclonal antibodies (mAbs) that would be capable of broadly neutralize viral targets, such as SARS-CoV, Influenza A and HIV-1. The isolation of broadly neutralizing monoclonal antibodies is relevant not only for serotherapy, but also for \u201canalytic vaccinology\u201d where such antibodies are used as probes to identify conserved epitopes that may be properly formulated as vaccines. Dr. Corti\u2019s work in the Weiss CAVD consortium has centered on the isolation of novel monoclonal antibodies that neutralize many strains of HIV-1 from selected patients of the Antwerp and London\u2019s cohorts. Three particularly interesting mAbs (HJ16, HGN194 and HK20) have been mapped to the CD4 binding site, the V3 loop and gp41 HR1, respectively, and characterized within the Weiss-VDC and by the Duke University VIMC. The initial results have recently been published (Corti D et al, 2010, PLoS One).<\/p>\n

\n\thttp:\/\/www.cavd.org\/Pages\/YoungInvestigator.aspx<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

on March 2, 2010 Davide Corti, PhD Institute for Research in Biomedicine Nominated by Prof. Robin Weiss Dr. Davide Corti is currently Director of the Antibody Discovery Unit at Humabs LLC, a spin-out company of the Institute of Research in Biomedicine. Dr. Corti completed his Ph.D. in Antonio Lanzavecchia\u2019s laboratory in December 2007 where he […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[16],"tags":[],"yoast_head":"\nIRB Scientist named "Young Researcher Honoree" - IRB USI<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/irb.usi.ch\/it\/news\/irb-scientist-named-young-researcher-honoree\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"IRB Scientist named "Young Researcher Honoree" - IRB USI\" \/>\n<meta property=\"og:description\" content=\"on March 2, 2010 Davide Corti, PhD Institute for Research in Biomedicine Nominated by Prof. Robin Weiss Dr. Davide Corti is currently Director of the Antibody Discovery Unit at Humabs LLC, a spin-out company of the Institute of Research in Biomedicine. 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