{"id":36784,"date":"2024-11-06T17:26:31","date_gmt":"2024-11-06T15:26:31","guid":{"rendered":"https:\/\/irb.usi.ch\/?p=36784"},"modified":"2024-11-06T17:41:03","modified_gmt":"2024-11-06T15:41:03","slug":"fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes","status":"publish","type":"post","link":"https:\/\/irb.usi.ch\/it\/news\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\/","title":{"rendered":"Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes"},"content":{"rendered":"

A <\/strong>review article published in <\/strong>Traffic by Maurizio Molinari\u2019s laboratory <\/strong>describes state-of-the art tools and methods to monitor intracellular traffic of lysosomal enzymes, as well as the catabolic processes of autophagy and heterophagy.<\/strong><\/p>\n

Bellinzona, November 07, 2024 – Lysosomal compartments control the clearance of cell-own material (autophagy) and of material that cells endocytose from the external environment (heterophagy) to warrant supply of nutrients, to eliminate macromolecules or parts of organelles present in excess, aged, or containing toxic material. Defective cargo delivery to lysosomal compartments is harmful to cells and organs since it causes accumulation of toxic compounds and defective organellar homeostasis. Moreover, inherited or sporadic mutations in lysosomal proteins and enzymes may hamper their folding in the endoplasmic reticulum (ER) and their lysosomal transport via the Golgi compartment, resulting in a series of debilitating diseases defined as lysosomal storage disorders.<\/p>\n

The published review describes tools and methods available to researchers to monitor intracellular transport events to endo-lysosomal compartments as well as autophagic and heterophagic fluxes to degradative organelles. It has been provided an up-to-date description of available single- and tandem-fluorescent reporters, mono- and multi-modal microscopy techniques, and artificial-intelligence analysis strategies. Tools developed in the last couple of years in our lab are also described. For example the tandem Halo-GFP reporter<\/a> to monitor intracellular trafficking events in time, by light and electron microscopy, biochemistry, and flow cytometry, and LysoQuant<\/a>, a deep-learning approach for the segmentation and classification of fluorescence images capturing multi parameters including size, distribution, number of acidic degradative compartments and cargo delivery within them.<\/p>\n

Photo (from left): Mikhail Rudinskiy and Diego Morone<\/p>\n

Link to the scientific article<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

A review article published in Traffic by Maurizio Molinari\u2019s laboratory describes state-of-the art tools and methods to monitor intracellular traffic of lysosomal enzymes, as well as the catabolic processes of autophagy and heterophagy. Bellinzona, November 07, 2024 – Lysosomal compartments control the clearance of cell-own material (autophagy) and of material that cells endocytose from the […]<\/p>\n","protected":false},"author":140,"featured_media":36783,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[16],"tags":[],"class_list":["post-36784","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"acf":[],"yoast_head":"\nFluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes - IRB USI<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/irb.usi.ch\/it\/news\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes - IRB USI\" \/>\n<meta property=\"og:description\" content=\"A review article published in Traffic by Maurizio Molinari\u2019s laboratory describes state-of-the art tools and methods to monitor intracellular traffic of lysosomal enzymes, as well as the catabolic processes of autophagy and heterophagy. Bellinzona, November 07, 2024 – Lysosomal compartments control the clearance of cell-own material (autophagy) and of material that cells endocytose from the […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/irb.usi.ch\/it\/news\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\/\" \/>\n<meta property=\"og:site_name\" content=\"IRB USI\" \/>\n<meta property=\"article:published_time\" content=\"2024-11-06T15:26:31+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-11-06T15:41:03+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/irb.usi.ch\/images\/misha-and-diego1.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"871\" \/>\n\t<meta property=\"og:image:height\" content=\"553\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Viviana Granelli\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Scritto da\" \/>\n\t<meta name=\"twitter:data1\" content=\"Viviana Granelli\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tempo di lettura stimato\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minuti\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/news\\\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/news\\\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\\\/\"},\"author\":{\"name\":\"Viviana Granelli\",\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/#\\\/schema\\\/person\\\/e3529a53127a78cf8ead39a83c87f29b\"},\"headline\":\"Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes\",\"datePublished\":\"2024-11-06T15:26:31+00:00\",\"dateModified\":\"2024-11-06T15:41:03+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/news\\\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\\\/\"},\"wordCount\":284,\"publisher\":{\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/news\\\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/irb.usi.ch\\\/images\\\/misha-and-diego1.jpeg\",\"articleSection\":[\"News\"],\"inLanguage\":\"it-IT\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/news\\\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\\\/\",\"url\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/news\\\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\\\/\",\"name\":\"Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes - IRB USI\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/news\\\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/news\\\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/irb.usi.ch\\\/images\\\/misha-and-diego1.jpeg\",\"datePublished\":\"2024-11-06T15:26:31+00:00\",\"dateModified\":\"2024-11-06T15:41:03+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/news\\\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\\\/#breadcrumb\"},\"inLanguage\":\"it-IT\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/irb.usi.ch\\\/it\\\/news\\\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"it-IT\",\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/news\\\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\\\/#primaryimage\",\"url\":\"https:\\\/\\\/irb.usi.ch\\\/images\\\/misha-and-diego1.jpeg\",\"contentUrl\":\"https:\\\/\\\/irb.usi.ch\\\/images\\\/misha-and-diego1.jpeg\",\"width\":871,\"height\":553},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/news\\\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"News\",\"item\":\"https:\\\/\\\/irb.usi.ch\\\/.\\\/news\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/#website\",\"url\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/\",\"name\":\"IRB USI\",\"description\":\"Institute for Research in Biomedicine\",\"publisher\":{\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"it-IT\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/#organization\",\"name\":\"IRB USI\",\"url\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"it-IT\",\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/irb.usi.ch\\\/images\\\/IRB-Usi.svg\",\"contentUrl\":\"https:\\\/\\\/irb.usi.ch\\\/images\\\/IRB-Usi.svg\",\"width\":98,\"height\":43,\"caption\":\"IRB USI\"},\"image\":{\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/irb.usi.ch\\\/it\\\/#\\\/schema\\\/person\\\/e3529a53127a78cf8ead39a83c87f29b\",\"name\":\"Viviana Granelli\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes - IRB USI","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/irb.usi.ch\/it\/news\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\/","og_locale":"it_IT","og_type":"article","og_title":"Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes - IRB USI","og_description":"A review article published in Traffic by Maurizio Molinari\u2019s laboratory describes state-of-the art tools and methods to monitor intracellular traffic of lysosomal enzymes, as well as the catabolic processes of autophagy and heterophagy. Bellinzona, November 07, 2024 – Lysosomal compartments control the clearance of cell-own material (autophagy) and of material that cells endocytose from the […]","og_url":"https:\/\/irb.usi.ch\/it\/news\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\/","og_site_name":"IRB USI","article_published_time":"2024-11-06T15:26:31+00:00","article_modified_time":"2024-11-06T15:41:03+00:00","og_image":[{"width":871,"height":553,"url":"https:\/\/irb.usi.ch\/images\/misha-and-diego1.jpeg","type":"image\/jpeg"}],"author":"Viviana Granelli","twitter_card":"summary_large_image","twitter_misc":{"Scritto da":"Viviana Granelli","Tempo di lettura stimato":"2 minuti"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/irb.usi.ch\/it\/news\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\/#article","isPartOf":{"@id":"https:\/\/irb.usi.ch\/it\/news\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\/"},"author":{"name":"Viviana Granelli","@id":"https:\/\/irb.usi.ch\/it\/#\/schema\/person\/e3529a53127a78cf8ead39a83c87f29b"},"headline":"Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes","datePublished":"2024-11-06T15:26:31+00:00","dateModified":"2024-11-06T15:41:03+00:00","mainEntityOfPage":{"@id":"https:\/\/irb.usi.ch\/it\/news\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\/"},"wordCount":284,"publisher":{"@id":"https:\/\/irb.usi.ch\/it\/#organization"},"image":{"@id":"https:\/\/irb.usi.ch\/it\/news\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\/#primaryimage"},"thumbnailUrl":"https:\/\/irb.usi.ch\/images\/misha-and-diego1.jpeg","articleSection":["News"],"inLanguage":"it-IT"},{"@type":"WebPage","@id":"https:\/\/irb.usi.ch\/it\/news\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\/","url":"https:\/\/irb.usi.ch\/it\/news\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\/","name":"Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes - IRB USI","isPartOf":{"@id":"https:\/\/irb.usi.ch\/it\/#website"},"primaryImageOfPage":{"@id":"https:\/\/irb.usi.ch\/it\/news\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\/#primaryimage"},"image":{"@id":"https:\/\/irb.usi.ch\/it\/news\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\/#primaryimage"},"thumbnailUrl":"https:\/\/irb.usi.ch\/images\/misha-and-diego1.jpeg","datePublished":"2024-11-06T15:26:31+00:00","dateModified":"2024-11-06T15:41:03+00:00","breadcrumb":{"@id":"https:\/\/irb.usi.ch\/it\/news\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\/#breadcrumb"},"inLanguage":"it-IT","potentialAction":[{"@type":"ReadAction","target":["https:\/\/irb.usi.ch\/it\/news\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\/"]}]},{"@type":"ImageObject","inLanguage":"it-IT","@id":"https:\/\/irb.usi.ch\/it\/news\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\/#primaryimage","url":"https:\/\/irb.usi.ch\/images\/misha-and-diego1.jpeg","contentUrl":"https:\/\/irb.usi.ch\/images\/misha-and-diego1.jpeg","width":871,"height":553},{"@type":"BreadcrumbList","@id":"https:\/\/irb.usi.ch\/it\/news\/fluorescent-reporters-imaging-and-artificial-intelligence-toolkits-to-monitor-and-quantify-autophagy-heterophagy-and-lysosomal-trafficking-fluxes\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/irb.usi.ch\/it\/"},{"@type":"ListItem","position":2,"name":"News","item":"https:\/\/irb.usi.ch\/.\/news\/"},{"@type":"ListItem","position":3,"name":"Fluorescent Reporters, Imaging, and Artificial Intelligence Toolkits to Monitor and Quantify Autophagy, Heterophagy, and Lysosomal Trafficking Fluxes"}]},{"@type":"WebSite","@id":"https:\/\/irb.usi.ch\/it\/#website","url":"https:\/\/irb.usi.ch\/it\/","name":"IRB USI","description":"Institute for Research in Biomedicine","publisher":{"@id":"https:\/\/irb.usi.ch\/it\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/irb.usi.ch\/it\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"it-IT"},{"@type":"Organization","@id":"https:\/\/irb.usi.ch\/it\/#organization","name":"IRB USI","url":"https:\/\/irb.usi.ch\/it\/","logo":{"@type":"ImageObject","inLanguage":"it-IT","@id":"https:\/\/irb.usi.ch\/it\/#\/schema\/logo\/image\/","url":"https:\/\/irb.usi.ch\/images\/IRB-Usi.svg","contentUrl":"https:\/\/irb.usi.ch\/images\/IRB-Usi.svg","width":98,"height":43,"caption":"IRB USI"},"image":{"@id":"https:\/\/irb.usi.ch\/it\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/irb.usi.ch\/it\/#\/schema\/person\/e3529a53127a78cf8ead39a83c87f29b","name":"Viviana Granelli"}]}},"_links":{"self":[{"href":"https:\/\/irb.usi.ch\/it\/wp-json\/wp\/v2\/posts\/36784","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/irb.usi.ch\/it\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/irb.usi.ch\/it\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/irb.usi.ch\/it\/wp-json\/wp\/v2\/users\/140"}],"replies":[{"embeddable":true,"href":"https:\/\/irb.usi.ch\/it\/wp-json\/wp\/v2\/comments?post=36784"}],"version-history":[{"count":2,"href":"https:\/\/irb.usi.ch\/it\/wp-json\/wp\/v2\/posts\/36784\/revisions"}],"predecessor-version":[{"id":36788,"href":"https:\/\/irb.usi.ch\/it\/wp-json\/wp\/v2\/posts\/36784\/revisions\/36788"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/irb.usi.ch\/it\/wp-json\/wp\/v2\/media\/36783"}],"wp:attachment":[{"href":"https:\/\/irb.usi.ch\/it\/wp-json\/wp\/v2\/media?parent=36784"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/irb.usi.ch\/it\/wp-json\/wp\/v2\/categories?post=36784"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/irb.usi.ch\/it\/wp-json\/wp\/v2\/tags?post=36784"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}